Results 111 to 120 of about 215,979 (293)

Development of a Jacketed Breathable Shake Flask With Process Monitoring, Control, and Bioreactor‐Like Performance

Biotechnology and Bioengineering, EarlyView.
This article presents the design and evaluation of a gas‐control jacket integrated with a breathable shake flask, enabling precise regulation of dissolved oxygen and carbon dioxide to improve scalability, process control, and culture performance in shaking bioreactors.
Vikash Kumar, Chad Sundberg, Venkatesh Srinivasan, Aaron Thole, Michael Tolosa, Govind Rao   +5 more
wiley   +1 more source

Succinate Promotes M1 Polarization of Intestinal Macrophages in Mice With Necrotizing Enterocolitis Through the PI3K/AKT Pathway

Pediatric Discovery
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disorder that frequently affects premature infants, and its pathogenesis is closely related to macrophage polarization.
Sha Liu, Fang‐Ling Tang, Xiao‐Lin Yan, Xiao‐Chen Liu, Qing Ai, Lu‐Quan Li, Lei Bao   +6 more
doaj   +1 more source

Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.

Cell, 2018
Krebs cycle intermediates traditionally link to oxidative phosphorylation whilst also making key cell components. It is now clear that some of these metabolites also act as signals.
M. Murphy, L. O'Neill
semanticscholar   +1 more source

All You Can Eat Yeast: Substituting Hexose Transporters With AtSWEET7 Alleviates Glucose Repression, Enabling Simultaneous Utilization of Sugars in Renewable Feedstocks

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Yeast sugar transporters have highly evolved for preferential glucose transport, a significant roadblock for utilizing non‐glucose sugars in renewable feedstocks such as lignocellulosic biomass. To enable simultaneous transport of multiple sugars, native hexose transporters were replaced by SWEET7p from Arabidopsis thaliana in engineered ...
Nurzhan Kuanyshev, Degaulle Dai, Jungyeon Kim, Nam Kyu Kang, Ming‐Hsun Cheng, Vijay Singh, Yong‐Su Jin   +6 more
wiley   +1 more source

The Role of Succinate in the Regulation of Intestinal Inflammation

Nutrients, 2018
Succinate is a metabolic intermediate of the tricarboxylic acid (TCA) cycle within host cells. Succinate is also produced in large amounts during bacterial fermentation of dietary fiber.
J. Connors, N. Dawe, J. V. van Limbergen
semanticscholar   +1 more source

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source

Succinate Regulates Endothelial Mitochondrial Function and Barrier Integrity

Antioxidants
Endothelial dysfunction is a hallmark of several pathological conditions, including cancer, cardiovascular disease and inflammatory disorders. In these conditions, perturbed TCA cycle and subsequent succinate accumulation have been reported.
Reham Atallah, Juergen Gindlhuber, Wolfgang Platzer, Rishi Rajesh, Akos Heinemann   +4 more
doaj   +1 more source

Utilization of fumarate by sulfur-reducing bacteria Desulfuromonas sp.

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2016
The main goal of the work was to study the utilization of fumarate by sulfur-reducing bacteria Desulfuromonas sp. under different growth conditions and accumulation of hydrogen sulfide by bacteria in the media with sulfur and different electron donors ...
O. Сhayka, T. Peretjatko, S. Gudz, A. Halushka   +3 more
doaj   +1 more source

An automated microfluidic biosensor with bispecific rabbit monoclonal antibody and nanozyme‐bioenzyme composite for dual antibiotic detection

BMEMat, EarlyView.
This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang, Yang Liu, Juntao Wang, Haichao Zhang, Wenlong Yu, Yaxin Sang, Yun Liu, Guangze Yang, Fang Gao, Shuo Wang, Shilun Feng, Xianghong Wang   +11 more
wiley   +1 more source

From Two‐Electron to Four‐Electron System: Electrolyte Regulation for Advanced Aqueous Zn–I2 Batteries

Carbon Energy, EarlyView.
This review systematically summarizes recent progress in electrolyte‐regulated aqueous Zn–I2 batteries (AZIBs). It outlines the fundamentals of AZIBs along with their main challenges, and then analyzes electrolyte‐engineering strategies that improve both two‐ and four‐electron reactions.
Yucong Wang, Ruifeng Huang, Zhangchi Yang, Shaojian Zhang, Lijing Yan, Weijie Chen, Xiaolong Lin, Yongjun Li, Shuxing Wu, Zhan Lin, Jun Lu   +10 more
wiley   +1 more source