Results 141 to 150 of about 218,507 (292)

An automated microfluidic biosensor with bispecific rabbit monoclonal antibody and nanozyme‐bioenzyme composite for dual antibiotic detection

BMEMat, EarlyView.
This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang, Yang Liu, Juntao Wang, Haichao Zhang, Wenlong Yu, Yaxin Sang, Yun Liu, Guangze Yang, Fang Gao, Shuo Wang, Shilun Feng, Xianghong Wang   +11 more
wiley   +1 more source

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.

Cell Metabolism, 2016
Vicky Lampropoulou, A. Sergushichev, M. Bambouskova, S. Nair, E. Vincent, Ekaterina Loginicheva, L. Cervantes-Barragan, Xiucui Ma, S. C. Huang, Takla Griss, C. Weinheimer, S. Khader, G. Randolph, E. Pearce, Russell G. Jones, A. Diwan, M. Diamond, M. Artyomov   +17 more
semanticscholar   +1 more source

Untargeted Metabolomics Reveals Seasonal and Tissue‐Specific Metabolic Shifts in Holothuria cinerascens

Chemistry &Biodiversity, EarlyView.
Untargeted metabolic profiling of three body tissues from Holothuria cinerascens in South Africa using 1H‐NMR and UPLC–QTOF–MS revealed distinct tissue‐specific and seasonal metabolic variations, with the body wall and gut/mesentery exhibiting high metabolite diversity.
Cassandra Upton, Gerhard Prinsloo, Paul Steenkamp, Moses Okpeku   +3 more
wiley   +1 more source

Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP

Canadian Journal of Statistics, EarlyView.
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang, Steven Chen, Raymond Balise, Jiming Jiang, Nagi Ayad, J. Sunil Rao   +5 more
wiley   +1 more source

Biodegradation of Poly(butylene succinate) Powder in a Controlled Compost at 58 °C Evaluated by Naturally-Occurring Carbon 14 Amounts in Evolved CO2 Based on the ISO 14855-2 Method [PDF]

, 2009
Masao Kunioka, Fumi Ninomiya, Masahiro Funabashi   +2 more
openalex   +1 more source

D-Alpha-Tocopheryl Poly(ethylene Glycol 1000) Succinate-Coated Manganese-Zinc Ferrite Nanomaterials for a Dual-Mode Magnetic Resonance Imaging Contrast Agent and Hyperthermia Treatments [PDF]

, 2022
Lin Wang, Syu-Ming Lai, Cun-Zhao Li, Hsiu‐Ping Yu, Parthiban Venkatesan, Ping‐Shan Lai   +5 more
openalex   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

Clinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan, Elizabeth Doolin, Dharam Paul, Julia Crossman, Michael Odontiadis, Philippe Danjou, Mark Smith, Spyros Papapetropoulos   +7 more
wiley   +1 more source

Clinical and laboratory evaluation of the efficiency of chronic hemodialysis treatment using acidosuccinate in patients with terminal renal failure

Терапевтический архив, 2013
AIM: To evaluate the efficiency of using a succinate-containing dialysis solution (SCDS) in terminal renal failure patients treated with chronic hemodialysis (CHD)/MATERIAL AND METHODS: Ninety patients from two hemodialysis units took part in the ...
A V Smirnov, O B Nesterova, E D Suglobova, R V Golubev, A N Vasil'ev, I A Vasil'eva, E V Verbitskaia, N Iu Korosteleva, E M Kostereva, É B Lebedeva, E N Levykina, K G Starosel'skiĭ, V A Lazeba   +12 more
doaj  

The functional indexes of RBCs and microcirculation in the traumatic brain injury with the action of 2-ethil-6-methil-3-hydroxypiridin succinate [PDF]

, 2021
Anastasia V. Polozova, A. Boyarinov Gennadii, O. Nikolsky Viktor, V. Zolotova Marina, V. Deryugina Anna   +4 more
openalex   +1 more source

Metabolic changes during cardiac regeneration in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich, Sofie Amalie Andersson, Morten Busk, Kasper Hansen, Casper Bindzus Foldager, Johan Palmfeldt, Asger Andersen, Michael Pedersen, Mikkel Vendelbo, Kirstine Lykke Nielsen, Henrik Lauridsen   +10 more
wiley   +1 more source