Results 151 to 160 of about 382,582 (334)

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

British Journal of Pharmacology, EarlyView.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha, Yun‐Seo Kil, Yunju Jo, Simmyung Yook, Ki Hyun Kim, Dongryeol Ryu, Joo‐Won Nam, Jee‐Heon Jeong   +7 more
wiley   +1 more source

Regulatory Properties of Perchlorate-extracted Succinate Dehydrogenase

, 1974
C.J. Coles, H.D. Tisdale, William C. Kenney, Thomas P. Singer   +3 more
openalex   +1 more source

Biochemical Diagnosis of Phaeochromocytoma and Paraganglioma in Children and Adolescents: A Retrospective Cohort Study

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Currently, it is unclear whether plasma free or 24‐h urinary fractionated metanephrines are preferable for diagnosis of phaeochromocytoma/paraganglioma (PPGL) in children. Objectives To investigate whether measurements of plasma free and 24‐h urinary fractionated metanephrines are reliable tests for screening for PPGL in children.
Kristin Potthoff, Tamara Prodanov, Lara M. Knigge, Angela Hübner, Stefan Bornstein, Jacques Lenders, Karel Pacak, Graeme Eisenhofer, Christina Pamporaki   +8 more
wiley   +1 more source

Inactivation of Succinate Dehydrogenase by N-Ethylmaleimide

, 1972
Norman T. Felberg, Thomas C. Hollocher
openalex   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Increased succinate dehydrogenase activity of lymphocytes in eczema

, 1977
WB Shelley, JS. Comaish
openalex   +2 more sources

Mitochondrial myopathy with succinate dehydrogenase and aconitase deficiency. Abnormalities of several iron-sulfur proteins. [PDF]

, 1993
Robin E. Hall, K. G. Henriksson, S. F. Lewis, Ronald G. Haller, N. G. Kennaway   +4 more
openalex   +1 more source

Enhanced mitochondrial respiration in peripheral blood mononuclear cells (PBMCs) from young children with overweight/obesity and insulin resistance

European Journal of Clinical Investigation, EarlyView.
We investigated measures of mitochondrial function in certain types of blood cells and metabolism in 65 children, 5–10 years old. Compared to children of normal weight (n = 20), children with overweight/obesity (n = 28) and especially those with insulin resistance (n = 17), differed in how their cells produced energy.
Eugenia Carvalho, Reid D. Landes, Matthew Cotter, Leanna M. Delhey, Elisabet Børsheim, Shannon Rose   +5 more
wiley   +1 more source

Characterization by electron paramagnetic resonance and studies on subunit location and assembly of the iron-sulfur clusters of Bacillus subtilis succinate dehydrogenase.

, 1985
Lars Hederstedt, J. J. Maguire, Alan J. Waring, T Ohnishi   +3 more
openalex   +1 more source

Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific

The FEBS Journal, EarlyView.
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty, Raz Ben‐David, Shenhav Shemer   +2 more
wiley   +1 more source