Results 141 to 150 of about 233,572 (253)

Common pathways and outliers in glucose catabolism across Trypanosomatidae

The FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes, Mayke B. Alencar, Ariel M. Silber, Ingrid Škodová‐Sveráková, Kristína Záhonová, Vyacheslav Yurchenko   +5 more
wiley   +1 more source

Oxaloacetate inhibition of succinate dehydrogenase: mechanism and physiological implications. [PDF]

Am J Physiol Cell Physiol
Sivitz WI, Yu L.
europepmc   +1 more source

Energetic dysregulations in psychotic disorders: Targets for new therapeutics

The FEBS Journal, EarlyView.
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson, Kai‐Christian Sonntag, Thao Do Vy Le, Kaitlin Shannon, Chao Wang, Fei Du, Xi Chen, Donna McPhie, Dost Ongur, Bruce Cohen, Virginie‐Anne Chouinard   +10 more
wiley   +1 more source

Modulation of succinate dehydrogenase in response to environmental stress conditions of hypobaria and hypoxia

, 1973
1. 1. An increase in the oxidation of succinate by hepatic mitochondria in rats exposed to hypoxia (O2-N2; 1:9, v/v) or hypobaria (0.5 atm) was observed which appears to be due to modification of the activity of the rate-limiting succinate dehydrogenase [
Susheela, L, Ramasarma, T
core  

Metabolic Profiling of Circulating and Tumour‐Infiltrating T Cells Uncovers Bioenergetic Checkpoints Linked With Immune and Clinical Skewing in Melanoma Patients

Immunology, EarlyView.
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque, Kareem Mahdy, Stephane Mouret, Sylvain Henry, Camille Niveau, Mélanie Cettour‐Cave, Martin Pelosse, Florence de Fraipont, Julie Charles, Andrei Turtoi, Philippe Saas, Caroline Aspord   +11 more
wiley   +1 more source

Role of Succinate Dehydrogenase in Age-Related Th17 Inflammation. [PDF]

Aging Cell
Ocegueda E, Chase G, Niceforo M, Javidan A, Gugliuzza L, Yu J, Kang RY, Lankowski A, Stefanik O, Leclerc K, Valentine Y, Drummond MJ, Deeney JT, Modica-Napolitano JS, Proctor EA, Hasturk H, Nikolajczyk BS, Bharath LP.   +17 more
europepmc   +1 more source

Engineered Yarrowia lipolytica inducing gene silencing confers control ability against gray mold in plants

Journal of Integrative Plant Biology, EarlyView.
Engineered the plant‐colonizing yeast Yarrowia lipolytica to produce and deliver double‐stranded RNAs targeting key genes of the gray mold fungus Botrytis cinerea produced a ‘living factory’ that continuously synthesizes and releases gene‐silencing molecules on plant surfaces, effectively suppressing the pathogen.
Mengjie Liu, Heng Shen, Jie Li, Mei Hao, Yelei Sun, Wenxing Liang   +5 more
wiley   +1 more source

Genetic, cellular, and environmental factors influencing tumourigenesis in carriers of succinate dehydrogenase germline mutations. [PDF]

Endocr Relat Cancer
Lim ES, Bayley JP, Gimenez-Roqueplo AP, Clifton-Bligh RJ, Richter S.   +4 more
europepmc   +1 more source

Light signaling controls chloroplast pyruvate metabolism through the STF1/2–PKP1 module in soybean

Journal of Integrative Plant Biology, EarlyView.
In soybean, light‐responsive proteins switch on GmPKP1, which boosts chloroplast pyruvate production. This increases pigments, photosynthesis, seed oil, pod number, and yield, revealing a new way that light boosts crop productivity. ABSTRACT Light signaling coordinates plant development with metabolism, but the link between photoreceptors and ...
Faming Lin, Xiaoran Wang, Chenhao Zhao, Shaolong Yang, Jingnan Xu, Hongyi Su, Ruixiang Lei, Yilei Xu, Jike Xue, Ming Chang, Fanjiang Kong, Ran Wang   +11 more
wiley   +1 more source

Polymorphic myopathological findings in a 77‐year‐old woman with oculo‐bulbo‐facial and distal weakness

Brain Pathology, EarlyView.
Michele Tosi, Angela Puma, Elena Faedo, Gianmarco Severa, Luisa Villa, Sabrina Sacconi, Edoardo Malfatti   +6 more
wiley   +1 more source