Results 151 to 160 of about 67,725 (262)

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha, Eloisa Vilas‐Boas, Camille C. Caldeira da Silva, Everton L. Vogt, Marcos Yoshinaga, Mariana Pacheco Teixeira de Carvalho, Maiara I. C. Queiroz, Tiago Eugênio Oliveira da Silva, Sayuri Miyamoto, Alicia J. Kowaltowski   +9 more
wiley   +1 more source

Effect of Porphyromonas gingivalis Infection on PGC‐1α in Skeletal Muscle After Endurance Training In Vivo

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objectives It is well known that Porphyromonas gingivalis, a major pathogen in periodontitis, causes systemic diseases. This study investigated the expression of PGC‐1α (the most important factor in muscle mitochondria synthesis) following endurance training to clarify the relationship between P.
Kairi Hayashi, Yasuo Takeuchi, Hiroaki Kobayashi, Gen Tanabe, Hiroshi Churei, Toshiaki Ueno, Kenji Fueki   +6 more
wiley   +1 more source

Two Cases of Succinate Dehydrogenase-Deficient Juvenile Gastric Gastrointestinal Stromal Tumor. [PDF]

Surg Case Rep
Fujimoto D, Inutake T, Takashima J, Taniguchi K, Kobayashi H.   +4 more
europepmc   +1 more source

Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +4 more
wiley   +1 more source

Succinate Dehydrogenase B (SDHB) Overexpression with Enzymatic Dysfunction Defines a Distinct Subtype of Undifferentiated Pleomorphic Sarcoma. [PDF]

Cancer Res Commun
Esperança-Martins M, Vasques H, Ravasqueira MS, Santos F, Fonseca F, Queiroz AS, Boavida J, Jordão DM, Soares do Brito J, Corredeira P, Martins M, Afonso Â, López JA, Huang RSP, Melo-Alvim C, Fernandes I, López-Presa D, Lemos MM, Van Tine BA, Bastos ACS, Casimiro S, Abecasis N, Costa L, Gonçalves E, Duarte IF, Dias S.   +25 more
europepmc   +1 more source

INHIBITION OF SUCCINIC DEHYDROGENASE BY OXALACETATE

Journal of Biological Chemistry, 1948
A B, PARDEE, V R, POTTER
openaire   +2 more sources

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Synchronous Succinate Dehydrogenase Subunit B (SDHB)-Deficient Gallbladder Paraganglioma and Periduodenal Well-Differentiated Neuroendocrine Tumor: A Case Report. [PDF]

Cureus
Lee S, Paz M, Gupta A, Schat R, Woehrle S, Park BU.   +5 more
europepmc   +1 more source

Effects of Exogenous Monosodium Glutamate on GABA Accumulation and Volatile/Nonvolatile Metabolites in Black Highland Barley

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Overview of MSG‐assisted GABA enrichment and associated changes in amino acid, fatty acid, and volatile metabolite profiles in germinated black highland barley. ABSTRACT γ‐Aminobutyric acid (GABA) is a functional amino acid with multiple health benefits; however, the mechanism of its enrichment in black highland barley, particularly through precursor ...
Xiaohang Lu, Nana Ma, Yuan Wang
wiley   +1 more source

Succinate Dehydrogenase Regulates Homeostasis and Metabolic Integrity of Alveolar Macrophages. [PDF]

Immune Netw
Song SG, Lee E, Koh J, Chung DH.
europepmc   +1 more source