Results 41 to 50 of about 433,622 (361)

Complete genome sequence of Syntrophobacter fumaroxidans strain (MPOB(T)). [PDF]

open access: yes, 2012
Syntrophobacter fumaroxidans strain MPOB(T) is the best-studied species of the genus Syntrophobacter. The species is of interest because of its anaerobic syntrophic lifestyle, its involvement in the conversion of propionate to acetate, H2 and CO2 during ...
Crable, Bryan R   +15 more
core   +2 more sources

Discovery of Pyrazine-Carboxamide-Diphenyl-Ethers as Novel Succinate Dehydrogenase Inhibitors via Fragment Recombination.

open access: yesJournal of Agricultural and Food Chemistry, 2020
The discovery of novel succinate dehydrogenase inhibitors (SDHIs) has attracted great attention worldwide. Herein, a fragment recombination strategy was proposed to design new SDHIs by understanding the ligand-receptor interaction mechanism of SDHIs ...
Hua Li   +5 more
semanticscholar   +1 more source

Biochemical and histochemical chenges in the activity of succinate dehydrogenase and ATP-ase in mitochondria of kidneys rats by acute intoxication

open access: yesJournal of Education, Health and Sport, 2018
Оbject of the study was to evaluate activities of succinate dehydrogenase and ATP-ase in mitochondria of kidney under conditions of toxic influence of 2,4-dinitrophenol. The experiment was conducted on 60 male albino rats. Toxic damage was caused by 0.1%
M. V. Dikal   +4 more
doaj   +3 more sources

A review of the tumour spectrum of germline succinate dehydrogenase gene mutations: Beyond phaeochromocytoma and paraganglioma

open access: yesClinical Endocrinology, 2020
The citric acid cycle, also known as the Krebs cycle, plays an integral role in cellular metabolism and aerobic respiration. Mutations in genes encoding the citric acid cycle enzymes succinate dehydrogenase, fumarate hydratase and malate dehydrogenase ...
J. MacFarlane   +11 more
semanticscholar   +1 more source

Proteogenomic characterization of cholangiocarcinoma

open access: yesHepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng   +18 more
wiley   +1 more source

Neck paraganglioma and follicular lymphoma: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Paragangliomas and pheochromocytomas are sympathetic or parasympathetic tumors derived from the paraganglia and the adrenal medulla, respectively.
Lara Marchetti   +6 more
doaj   +1 more source

Breast cancer–associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells

open access: yesScience Signaling, 2020
Macrophage-secreted TGF-β promotes glycolysis in tumor cells to support angiogenesis and immunosuppression. TAMs reprogram tumor metabolism Macrophages in the tumor microenvironment [called tumor-associated macrophages (TAMs)] often support tumor growth ...
Valentí Gómez   +13 more
semanticscholar   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Effects of filaricidal drugs on longevity and enzyme activities of the microfilariae of Setaria cervi in white rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Objective: To analyse the efficacy of diethylcarbamazine (DEC), tetramisole and chlorpromazine on the longevity and activity of glucose-6-phosphatase and succinate dehydrogenase in the microfilariae recovered from the peripheral circulation of the rats ...
Haytham Ahmed Zakai, Wajihullah Khan
doaj   +1 more source

Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]

open access: yes, 2014
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia   +2 more
core   +1 more source

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