Results 241 to 250 of about 3,444 (280)

Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat. [PDF]

J Am Chem Soc
Wu C, Meuser ME, Rey JS, Meshkin H, Yang R, Devarkar SC, Freniere C, Shi J, Aiken C, Perilla JR, Xiong Y.   +10 more
europepmc   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Itaconate potentiates hepatic gluconeogenesis through NRF2 induction. [PDF]

PLoS One
El-Derany MO, Ramakrishnan SK, Li Y, Buscher K, Jarad CA, Schaller ML, Cantwell M, Vigil TM, Frieler RA, Sajjakulnukit P, Lyssiotis CA, Mortensen RM, Shah YM.   +12 more
europepmc   +1 more source

Functional divergence of tandem duplicate SCPL acyltransferase genes reveals convergent evolution of chicoric acid biosynthesis. [PDF]

Sci Adv
Xiang Y, Liang T, Yang R, Wang H, Fernie AR, Zhang Y, Fu R.   +6 more
europepmc   +1 more source

4-Octyl Itaconate ameliorates diesel exhaust particle-induced oxidative stress in nasal epithelial cells. [PDF]

Front Immunol
Steppuhn H, Hohenberger K, Mittler S, Trump S, Carvalho C, Rauh M, Wild AB, Papadopoulos NG, Finotto S.   +8 more
europepmc   +1 more source

Neutrophil Irg1/itaconate axis protects against experimental colitis by suppressing local inflammation and maintaining hematopoietic homeostasis. [PDF]

Mol Biomed
Zhao N, Wang G, Long S, Chen Y, Gao J, Lv X, Ran X, Jia Y, Wang T.   +8 more
europepmc   +1 more source

The combination of nitrogen fertilizers and EDDS enhances remediation efficiency of Bidens pilosa L. in Cd-contaminated soils. [PDF]

Sci Rep
Chen Y, Cao B, Lu Y, Zheng Y, Sun Y, Li Q, Yuan Q, Zhang X.   +7 more
europepmc   +1 more source

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2-Aminopyridinium–succinate–succinic acid (2/1/1)

Acta Crystallographica Section C Crystal Structure Communications, 2002
In the title compound, 2C(5)H(7)N(2)(+).C(4)H(4)O(4)(2-).C(4)H(6)O(4), cyclic eight-membered hydrogen-bonded rings exist involving 2-aminopyridinium and succinate ions. The succinic acid and succinate moieties lie on inversion centres. Succinic acid molecules and succinate ions are linked into zigzag chains by O-H.O hydrogen bonds, with O.O distances ...
Buyukungor, O, Odabaşoğlu, Mustafa
openaire   +2 more sources

Desvenlafaxine succinate monohydrate

Acta Crystallographica Section C Crystal Structure Communications, 2008
The title compound {systematic name: [2-(1-hydroxycyclohexyl)-2-(4-hydroxyphenyl)ethyl]dimethylammonium 3-carboxypropanoate monohydrate}, C(16)H(26)NO(2)(+) x C(4)H(5)O(4)(-) x H(2)O, is a succinate salt of O-desmethylvenlafaxine (desvenlafaxine). The present structure is one of four reported polymorphs of this salt, which is a new antidepressant drug.
Nalivela, Venu, Bukkapattanam R, Sreekanth, Thaimattam, Ram, Surya, Devarakonda   +3 more
openaire   +2 more sources

Colorimetric determination of succinic acid using yeast succinate dehydrogenase

Analytical Biochemistry, 1978
An enzymatic method for the rapid determination of succinic acid in biological fluids was developed utilizing yeast mitochondria as a source of succinate dehydrogenase. The yeast enzyme catalyzes a complete stoichiometric reduction of 2- (p-iodophenyl)-3-(p-nitrophenyl)-5-tetrazolium chloride to a red formazan.
A B, Valle, A D, Panek, J R, Mattoon
openaire   +2 more sources