Results 181 to 190 of about 5,204,655 (327)

Epilepsy Phenotype and EEG Finding of Rhythmic High‐Amplitude Delta With Superimposed Spikes (RHADS) in Succinate Dehydrogenase Deficiency

open access: yesJIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Succinate dehydrogenase (SDH) serves a dual function as complex II of the electron transport chain and an enzyme of the tricarboxylic acid cycle. Pathogenic variants in subunits of SDH result in diverse clinical presentations, including typically autosomal recessive neurodegenerative disorders. Biallelic variants in the SDHA subunit most often
Aaron B. Bowen   +7 more
wiley   +1 more source

Prospecting technology and economic potential to produce bio-succinic acid: a review. [PDF]

open access: yesBiotechnol Rep (Amst)
Silva DAS   +6 more
europepmc   +1 more source

Esterification of succinic acid [PDF]

open access: yesAmerican Journal of Science, 1907
I. K. Phelps, J. L. Hubbard
openaire   +1 more source

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem   +9 more
wiley   +1 more source

A la carte bioprospecting of substrate‐selective laccases via high‐throughput computational enzyme–substrate interaction profiling

open access: yesProtein Science, Volume 35, Issue 3, March 2026.
Abstract Laccases are versatile, multicopper oxidases with broad biotechnological applications due to their ability to oxidize a wide range of substrates. Here, we introduce a computational pipeline that combines sequence filtering, Monte Carlo simulations, and quantum mechanical spin density calculations to identify laccase candidates tailored to ...
Ruite Xiang   +5 more
wiley   +1 more source

The cytokinesis regulator RacGAP1 is a Rac1‐specific GAP on membranes

open access: yesProtein Science, Volume 35, Issue 3, March 2026.
Abstract Rho family small GTPases are essential for cytokinesis completion. RacGAP1, a dimeric multidomain protein with a lipid‐binding C1 domain and a GTPase‐activating protein (GAP) domain, is a major regulator in this process. However, despite many cellular and biochemical studies, whether RhoA or Rac1 is the actual substrate inactivated by RacGAP1 ...
Pavlina Dubois   +5 more
wiley   +1 more source

Preliminary Batch Tests for Succinic Acid Production and Co-products Through Fermentation by Actinobacillus Succinogenes

open access: yesChemical Engineering Transactions
Succinic acid is one of the most used building blocks in different production chains. Conventionally, this carboxylic acid is produced through petrochemical routes, but can be also produced via biological routes.
Raffaele Loffredo   +3 more
doaj  

Hyaluronic and Succinic Acid: New Biostimulating Combination to Counteract Dermal and Subcutaneous Aging. [PDF]

open access: yesInt J Mol Sci
Martinez-Gutierrez A   +5 more
europepmc   +1 more source

Bismuth Bicycles

open access: yesJournal of Peptide Science, Volume 32, Issue 3, March 2026.
Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss   +8 more
wiley   +1 more source

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