Metabolic Regulation of Organic Acid Biosynthesis in Actinobacillus succinogenes [PDF]
Frontiers in Bioengineering and Biotechnology, 2019 Actinobacillus succinogenes is one of the most promising strains for succinic acid production; however, the lack of efficient genetic tools for strain modification development hinders its further application.
Fengxue Xin, Min Jiang, Weiliang Dong
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Succinic Acid Production With Actinobacillus succinogenes –Influence of an Electric Potential on the Intercellular NADH/NAD+ Balance [PDF]
Engineering in Life SciencesBioelectrochemical systems (BESs) offer a sustainable method for chemical production, including the enhanced production of succinic acid. By combining fermentation with BES, it could be possible to achieve sustainable succinic acid production and CO2 ...
Jan‐Niklas Hengsbach +5 more
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Transcriptome analysis and anaerobic C 4 ‐dicarboxylate transport in Actinobacillus succinogenes [PDF]
MicrobiologyOpen, 2018 A global transcriptome analysis of the natural succinate producer Actinobacillus succinogenes revealed that 353 genes were differentially expressed when grown on various carbon and energy sources, which were categorized into six functional groups.
In-Geol Choi, Ok Bin Kim, Mi Na Rhie
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Development of highly efficient and specific base editors in Actinobacillus succinogenes for enhancing succinic acid production [PDF]
Biotechnology for Biofuels and Bioproducts, 2023 The production of bio-succinic acid (SA) from renewable feedstocks is a promising and sustainable approach to mitigating the high carbon emissions associated with the current energy crisis.
Chunmei Chen +3 more
doaj +2 more sources
Comparative Transcriptome Analysis Reveals the Molecular Mechanisms of Acetic Acid Reduction by Adding NaHSO3 in Actinobacillus succinogenes GXAS137 [PDF]
Polish Journal of Microbiology, 2023 Acetic acid (AC) is a major by-product from fermentation processes for producing succinic acid (SA) using Actinobacillus succinogenes. Previous experiments have demonstrated that sodium bisulfate (NaHSO3) can significantly decrease AC production by A ...
Li Shiyong +5 more
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Biotechnological enhancement of lactic acid conversion from pretreated palm kernel cake hydrolysate by Actinobacillus succinogenes 130Z [PDF]
Scientific Reports, 2023 The aim of this study was to establish an improved pretreatment and fermentation method i.e. immobilized cells for high recovery of fermentable sugars from palm kernel cake (PKC) and its effects on fermentability performance by Actinobacillus ...
Nuraishah Abd Rahim +5 more
doaj +2 more sources
Effects of down-regulation of ackA expression by CRISPR-dCpf1 on succinic acid production in Actinobacillus succinogenes [PDF]
AMB Express, 2023 Keypoints CRISPRi based on FnCpf1 and SpCas9opt was established in A. succinogenes. The target gene, ackA was repressed ~ eightfold by CRISPR-dCpf1. Repression of ackA increased succinate yield compared with ackA deletion.
Chunmei Chen, Pu Zheng
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One step forward, two steps back: Transcriptional advancements and fermentation phenomena in Actinobacillus succinogenes 130Z. [PDF]
PLoS ONE, 2021 Within the field of bioproduction, non-model organisms offer promise as bio-platform candidates. Non-model organisms can possess natural abilities to consume complex feedstocks, produce industrially useful chemicals, and withstand extreme environments ...
Dianna S Long +4 more
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Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes. [PDF]
Biotechnol Appl BiochemABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Vallejo-Giraldo A +7 more
europepmc +2 more sources
Prediction of reaction knockouts to maximize succinate production by Actinobacillus succinogenes. [PDF]
PLoS ONE, 2018 Succinate is a precursor of multiple commodity chemicals and bio-based succinate production is an active area of industrial bioengineering research. One of the most important microbial strains for bio-based production of succinate is the capnophilic gram-
Ambarish Nag +3 more
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