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Sucralose induces biochemical responses in Daphnia magna.
PLoS ONE, 2014 The intense artificial sweetener sucralose has no bioconcentration properties, and no adverse acute toxic effects have been observed in standard ecotoxicity tests, suggesting negligible environmental risk.
Ann-Kristin Eriksson Wiklund +3 more
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Effects of sweetener sucralose on diet preference, growth performance and hematological and biochemical parameters of weaned piglets [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 Objective Two experiments were conducted to investigate the effects of dietary sucralose on diet preference and growth performance of weaned piglets, and a third experiment was a 28-d safety study to examine if high-dose sucralose could affect the health
Wenwei Zhang +5 more
doaj +1 more source
Acta Portuguesa de Nutrição, 2021 O uso de edulcorantes é uma estratégia para a diminuição do consumo de açúcar. A sucralose é dos mais utilizados, sendo descrita como segura por diferentes entidades de referência, como a Autoridade Europeia para a Segurança Alimentar e a Food & Drug Administration.
Correia,Daniela +2 more
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Low Doses of Sucralose Alter Fecal Microbiota in High-Fat Diet-Induced Obese Rats
Frontiers in Nutrition, 2021 Artificial sweeteners (AS) have been widely used as sugar substitutes to reduce calorie intake. However, it was reported that high doses of AS induced glucose intolerance via modulating gut microbiota.
Minchun Zhang +9 more
doaj +1 more source
Frontiers in Nutrition, 2022 Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, and it is strongly associated with obesity. To combat obesity, artificial sweeteners are often used to replace natural sugars, and sucralose is one of the most ...
Hung-Tsung Wu +9 more
doaj +1 more source
Microorganisms, 2022 Sucralose consumption alters microbiome and carbohydrate metabolism in mouse models. However, there are no conclusive studies in humans. Our goals were to examine the effect of sucralose consumption on the intestinal abundance of bacterial species ...
Lucía A. Méndez-García +15 more
doaj +1 more source
Frontiers in Nutrition, 2022 Sucralose is one of the most widely used artificial sweeteners used by the food industry to reduce the calorie density of their products. Although broadly regarded as innocuous, studies show contrasting results depending on whether the research subjects ...
Pamela Pino-Seguel +11 more
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Sucralose Stimulates Mitochondrial Bioenergetics in Caco-2 Cells
Frontiers in Nutrition, 2021 Sucralose is a non-caloric artificial sweetener widely used in processed foods that reportedly affects energy homeostasis through partially understood mechanisms. Mitochondria are organelles fundamental for cellular bioenergetics that are closely related
Juan Carlos Bórquez +9 more
doaj +1 more source
Sucralose Targets the Insulin Signaling Pathway in the SH-SY5Y Neuroblastoma Cell Line
Metabolites, 2023 Sucralose is widely used as a non-nutritive sweetener (NNS). However, in order to justify its use as a non-nutritive food additive, sucralose would have to be metabolically neutral.
Marina Čović +7 more
doaj +1 more source
Nutrition Journal, 2020 Background Non-nutritive sweeteners (NNS) are widely consumed by humans due to their apparent innocuity, especially sucralose. However, several studies link sucralose consumption to weight gain and metabolic derangements, although data are still ...
Nallely Bueno-Hernández +11 more
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