Maintenance work ahead: cellulose links cell wall construction and sucrose transport. [PDF]
Alonso Baez L.
europepmc +1 more source
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang +17 more
wiley +1 more source
Ethanol Self-Administration Reduces mGlu2/3 Protein Expression in the Nucleus Accumbens and mGlu2/3 Activation Suppresses Binge Drinking in Male Mice. [PDF]
Modrak CG +6 more
europepmc +1 more source
Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
Integrated transcriptomic and metabolomic analyses reveal the molecular mechanisms of sugar accumulation and yield trade-off in sugar beet. [PDF]
Bai X +16 more
europepmc +1 more source
By altering surface chemical bonds to prolong relaxation time and shift absorption to lower frequencies, SiC/rare earth–sulfur (RE─S, RE = La, Ce, Pr, Sm, Gd, Er) materials achieve excellent low‐frequency electromagnetic wave absorption under extreme conditions, offering a new direction for designing high‐performance SiC‐based absorbers.
Zhanming Wu +5 more
wiley +1 more source
Machine-learning-driven rational design of gelatin architectures: saccharide derivatives as structural plasticizers under low water content. [PDF]
Yazawa G, Masuda M, Osawa S.
europepmc +1 more source
A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma +22 more
wiley +1 more source
Extensive sucrose cycling through the fructan pool of a C3 grass across a 200 to 800 μmol mol-1 atmospheric CO2 gradient. [PDF]
Zhu J +7 more
europepmc +1 more source
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori +10 more
wiley +1 more source

