Results 231 to 240 of about 648,675 (306)

Pain Management During Neonatal Blood Sampling: An Overview of Systematic Reviews. [PDF]

Paediatr Neonatal Pain
Lord LG, Harding JE, Crowther CA, Lin L.
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

A mouse model of oxycodone reward following its oral self-administration in a sweetened solution. [PDF]

Front Behav Neurosci
Rounama S, Meziem P, Hamid A, Era IH, Lutfy K.   +4 more
europepmc   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Stevia-derived sweeteners in reduced-sugar foods: formulation strategies, sensory optimization, nutritional evidence, and safety perspectives. [PDF]

Front Nutr
Wang L, Chang T, Jia W, Chen J, Li L, Zhang T, Wang B, Dong C, Cui Y, Liao X.   +9 more
europepmc   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Limited sucrose intake produces subregion-specific remodeling of perineuronal nets in the medial prefrontal cortex. [PDF]

Brain Struct Funct
Nashawi H, Foltz CT, Oh N, Santiago EA, Selm DR, Herman JP, Ulrich-Lai YM.   +6 more
europepmc   +1 more source

Cytoplasmic fluidity couples nutrient availability and enterocyte fate in vivo. [PDF]

Proc Natl Acad Sci U S A
Nakamura Y, Morikawa M, Takano T, Yoo SK.   +3 more
europepmc   +1 more source

Starch Degradation and Soluble Sugar Accumulation Are Associated with Cold Tolerance in Winter Rapeseed (<i>Brassica napus</i> L.). [PDF]

Plants (Basel)
Long L, Shi Y, Pu Y, Wu J, Ma L, Liu L, Yang G, Fan T, Wang W, Sun W.   +9 more
europepmc   +1 more source