Results 41 to 50 of about 18,516 (115)

First report of dengue virus among febrile malaria positive and negative patients in Nyala city, Western Sudan

Journal of Microbiology and Infectious Diseases
Background: The mosquito borne dengue fever and malaria -; are major public health concerns in tropical settings. They are highly prevalent and considered one of the main etiology of febrile illnesses in Sudan.
Smah Ishag, Abdel Rahim M El Hussein, Isam M Elkhidir, Khalid A Enan   +3 more
doaj   +1 more source

Yellow Fever Outbreak, Southern Sudan, 2003

Emerging Infectious Diseases, 2004
In May 2003, an outbreak of fatal hemorrhagic fever, caused by yellow fever virus, occurred in southern Sudan. Phylogenetic analysis showed that the virus belonged to the East African genotype, which supports the contention that yellow fever is endemic ...
Clayton O. Onyango, Antoinette A. Grobbelaar, Georgina V.F. Gibson, Rosemary C. Sang, Abdourahmane Sow, Robert Swanepoel, Felicity J. Burt   +6 more
doaj   +1 more source

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

Nature Communications, 2019
Current experimental monoclonal antibodies (mAbs) for Ebola virus (EBOV) post-exposure immunotherapy are ineffective against Sudan (SUDV) or Marburg virus (MARV).
Jennifer M. Brannan, Shihua He, Katie A. Howell, Laura I. Prugar, Wenjun Zhu, Hong Vu, Sergey Shulenin, Shweta Kailasan, Henna Raina, Gary Wong, Md Niaz Rahim, Logan Banadyga, Kevin Tierney, Xuelian Zhao, Yuxing Li, Frederick W. Holtsberg, John M. Dye, Xiangguo Qiu, M. Javad Aman   +18 more
doaj   +1 more source

Nosocomial Outbreak of Crimean-Congo Hemorrhagic Fever, Sudan

Emerging Infectious Diseases, 2010
To confirm the presence of Crimean-Congo hemorrhagic fever in Sudan, we tested serum of 8 patients with hemorrhagic fever in a rural hospital in 2008. Reverse transcription–PCR identified Crimean-Congo hemorrhagic fever virus. Its identification as group
Imadeldin E. Aradaib, Bobbie R. Erickson, Mubarak E. Mustafa, Marina L. Khristova, Nageeb S. Saeed, Rehab M. Elageb, Stuart T. Nichol   +6 more
doaj   +1 more source

Rational design of next-generation filovirus vaccines combining glycoprotein stabilization and nanoparticle display with glycan modification

Nature Communications
Filoviruses pose a significant threat to human health due to frequent outbreaks and high mortality. Although two vector-based vaccines are available for Ebola virus, a broadly protective filovirus vaccine remains elusive.
Yi-Zong Lee, Yi-Nan Zhang, Maddy L. Newby, Garrett Ward, Keegan Braz Gomes, Sarah Auclair, Connor DesRoberts, Joel D. Allen, Andrew B. Ward, Robyn L. Stanfield, Linling He, Max Crispin, Ian A. Wilson, Jiang Zhu   +13 more
doaj   +1 more source

Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse.

PLoS Pathogens
Viral haemorrhagic fevers (VHF) pose a significant threat to human health. In recent years, VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial morbidity and mortality in West and Central Africa.
Amy Flaxman, Sarah Sebastian, Sofia Appelberg, Kuan M Cha, Marta Ulaszewska, Jyothi Purushotham, Ciaran Gilbride, Hannah Sharpe, Alexandra J Spencer, Sagida Bibi, Daniel Wright, Isabel Schmidt, Stuart Dowall, Linda Easterbrook, Stephen Findlay-Wilson, Sarah Gilbert, Ali Mirazimi, Teresa Lambe   +17 more
doaj   +1 more source

Rift Valley Fever, Sudan, 2007 and 2010

Emerging Infectious Diseases, 2013
To elucidate whether Rift Valley fever virus (RVFV) diversity in Sudan resulted from multiple introductions or from acquired changes over time from 1 introduction event, we generated complete genome sequences from RVFV strains detected during the 2007 ...
Imadeldin E. Aradaib, Bobbie R. Erickson, Rehab M. Elageb, Marina L. Khristova, Serena A. Carroll, Isam M. Elkhidir, Mubarak E. Karsany, AbdelRahim E. Karrar, Mustafa I. Elbashir, Stuart T. Nichol   +9 more
doaj   +1 more source

Resurgence of Ebola in Uganda: Response Strategies, Lessons Learned, and Future Directions

Health Science Reports
Introduction The recent resurgence of Ebola virus disease (EVD), specifically the Sudan virus strain, in Uganda highlights the ongoing threat of emerging infectious diseases.
Majani Edward, Sylivester Muhigi, Joan Mundua, Ally Ally   +3 more
doaj   +1 more source

Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda. [PDF]

J Virol, 2023
Balinandi S, Whitmer S, Mulei S, Nassuna C, Pimundu G, Muyigi T, Kainulainen M, Shedroff E, Krapiunaya I, Scholte F, Nyakarahuka L, Tumusiime A, Kyondo J, Baluku J, Kiconco J, Harris JR, Ario AR, Kagirita A, Bosa HK, Ssewanyana I, Nabadda S, Mwebesa HG, Aceng JR, Atwine D, Lutwama JJ, Shoemaker TR, Montgomery JM, Kaleebu P, Klena JD.   +28 more
europepmc   +1 more source

In silico exploration of deep-sea fungal metabolites as inhibitor of Ebola and Marburg VP35 and VP40.

PLoS ONE
VP30 and VP40 proteins of Ebola and Marburg viruses have been recognized as potential targets for antiviral drug development due to their essential roles in the viral lifecycle.
Abdullah R Alanzi, Mohammed F Alajmi, Mohammed S Al-Dosari, Mohammad K Parvez, Moneerah J Alqahtani   +4 more
doaj   +1 more source