Results 31 to 40 of about 5,831 (244)

Sudden unexpected death in epilepsy: A bibliometric overview

Frontiers in Neurology, 2023
The mechanism of sudden unexpected death in epilepsy (SUDEP) is elusive and many questions remain unanswered. Autopsy is generally unhelpful in providing evidence for the cause of death, as pathological changes may be on the molecular level.
Fang Tong, Fang Tong, Jian Lin, Jian Lin, Zixuan Zeng, Qi Wang, Zhifang Yang, Zhifang Yang, Yehui Lv, Yehui Lv   +9 more
doaj   +1 more source

Loss‐of‐function variants in Kv11.1 cardiac channels as a biomarker for SUDEP

Annals of Clinical and Translational Neurology, 2021
Objective To compare the frequency and impact on the channel function of KCNH2 variants in SUDEP patients with epilepsy controls comprising patients older than 50 years, a group with low SUDEP risk, and establish loss‐of‐function KCNH2 variants as ...
Ming S. Soh, Richard D. Bagnall, Mark F. Bennett, Lauren E. Bleakley, Erlina S. Mohamed Syazwan, A. Marie Phillips, Mathew D. F. Chiam, Chaseley E. McKenzie, Michael Hildebrand, Douglas Crompton, Melanie Bahlo, Christopher Semsarian, Ingrid E. Scheffer, Samuel F. Berkovic, Christopher A. Reid   +14 more
doaj   +1 more source

Ictal ECG-based assessment of sudden unexpected death in epilepsy

Frontiers in Neurology, 2023
IntroductionPrevious case-control studies of sudden unexpected death in epilepsy (SUDEP) patients failed to identify ECG features (peri-ictal heart rate, heart rate variability, corrected QT interval, postictal heart rate recovery, and cardiac rhythm ...
Adam C. Gravitis, Uilki Tufa, Katherine Zukotynski, Katherine Zukotynski, David L. Streiner, Daniel Friedman, Juliana Laze, Yotin Chinvarun, Orrin Devinsky, Richard Wennberg, Peter L. Carlen, Peter L. Carlen, Berj L. Bardakjian, Berj L. Bardakjian   +13 more
doaj   +1 more source

Hemosiderin, a possible biomarker for sudep?

Revista Neurociências, 2021
Epilepsy is one of the neurological diseases of complex etiology that affects around 50 million people worldwide and is characterized by abnormal electrical activity and recurrent seizures. Uncontrolled generalized repetitive tonic-clonic seizures (GTCS) are the main causes of unexpected sudden death in epilepsy (SUDEP).
Pereira, Andressa Sampaio, Brandão, Patrícia de Morais Ferreira, Auzmendi, Jerónimo Andrés, Lazarowski, Alberto Jorge   +3 more
openaire   +3 more sources

Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet Syndrome

eNeuro, 2022
Visual Abstract Dravet syndrome (DS) is a catastrophic form of pediatric epilepsy mainly caused by noninherited mutations in the SCN1A gene. DS patients suffer severe and life-threatening focal and generalized seizures which are often refractory to ...
R. Gerbatin, Joana Augusto, G. Morris, Aoife Campbell, J. Worm, E. Langa, C. Reschke, D. Henshall   +7 more
semanticscholar   +1 more source

Does sudden unexpected death in children with epilepsy occur more frequently in those with high seizure frequency? Morte súbita em crianças com epilepsia ocorre naquelas que apresentam maior frequência de crises?

Arquivos de Neuro-Psiquiatria, 2009
People with epilepsy are more likely to die prematurely and the most common epilepsy-related category of death is sudden unexpected death in epilepsy (SUDEP).
Vera C. Terra, Fulvio A. Scorza, Américo C. Sakamoto, Kylvia G.F.D. Pinto, Regina M.F. Fernandes, Ricardo M. Arida, Esper A. Cavalheiro, Hélio R. Machado   +7 more
doaj   +1 more source

Sudden Unexpected Death in Epilepsy: A Case Report

Archives of Epilepsy, 2018
Sudden unexpected death in epilepsy (SUDEP) is a serious problem, and its importance has increased in recent years. It is responsible for the death of 17% of epilepsy patients. As the age of onset rises, the risk increases.
Gülser KARADABAN EMİR, Yasemin ÜNAL, Dilek ASLAN ÖZTÜRK, Gülnihal KUTLU   +3 more
doaj   +1 more source

Stratifying sudden death risk in adults with drug‐resistant focal epilepsy: The SUDEP‐CARE score

European Journal of Neurology, 2022
A clinical risk score for sudden unexpected death in epilepsy (SUDEP) in patients with drug‐resistant focal epilepsy could help improve prevention.
C. Serrand, S. Rheims, M. Faucanié, A. Crespel, V. Dinkelacker, W. Szurhaj, A. Biraben, F. Bartolomei, Nathalie de Grissac, E. Landre, M. Denuelle, L. Vercueil, C. Marchal, L. Maillard, P. Derambure, Sophie Dupont, V. Navarro, T. Mura, A. Jaussent, V. Macioce, Ryvlin Philippe, M. Picot   +21 more
semanticscholar   +1 more source

Hypothalamic-Pituitary-Adrenal Axis Dysfunction Elevates SUDEP Risk in a Sex-Specific Manner. [PDF]

eNeuro
Epilepsy is often comorbid with psychiatric illnesses, including anxiety and depression. Despite the high incidence of psychiatric comorbidities in people with epilepsy, few studies address the underlying mechanisms.
Basu T, Antonoudiou P, Weiss GL, Coleman EM, David J, Friedman D, Laze J, Strain MM, Devinsky O, Boychuk CR, Maguire J.   +10 more
europepmc   +2 more sources

Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP

Brain Pathology, 2022
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP.
S. Patodia, Alyma Somani, Joan Y. W. Liu, Alice Cattaneo, Beatrice Paradiso, Maria Garcia, Muhammad Othman, B. Diehl, O. Devinsky, J. D. Mills, J. Foong, M. Thom   +11 more
semanticscholar   +1 more source