Results 31 to 40 of about 7,651 (258)

Ictal ECG-based assessment of sudden unexpected death in epilepsy

open access: yesFrontiers in Neurology, 2023
IntroductionPrevious case-control studies of sudden unexpected death in epilepsy (SUDEP) patients failed to identify ECG features (peri-ictal heart rate, heart rate variability, corrected QT interval, postictal heart rate recovery, and cardiac rhythm ...
Adam C. Gravitis   +13 more
doaj   +1 more source

Risk Assessment for Sudden Death in Epilepsy: The SUDEP-7 inventory

open access: yesFrontiers in Neurology, 2015
Background: Sudden Unexpected Death in Epilepsy (SUDEP) is a major cause of death in those with drug resistant epilepsy. There is a need for inventories and biomarkers associated with the risk for SUDEP.
Jennifer L Novak   +4 more
doaj   +1 more source

The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. [PDF]

open access: yes, 2016
The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing
Calton, Michele A   +4 more
core   +2 more sources

Alternating Hemiplegia and Cardiac Dysrhythmia

open access: yesPediatric Neurology Briefs, 2015
Investigators at the National Hospital for Neurology and Neurosurgery, Queen Square, London, and multiple centers in the UK, Europe, US, Melbourne, Australia, and Canada, analyzed ECG recordings of 52 patients with alternating hemiplegia from 9 countries;
J. Gordon Millichap
doaj   +1 more source

Seizure Clusters: Morbidity and Mortality

open access: yesFrontiers in Neurology, 2021
Seizure clusters, an intermediate between single seizure and status epilepticus, are associated with morbidity, impaired quality of life, and premature mortality.
Kristie Bauman, Orrin Devinsky
doaj   +1 more source

Sudden unexpected death in epilepsy disclosure causes anxiety in patients with epilepsy: a Chinese questionnaire survey

open access: yesFrontiers in Neurology, 2023
Background and objectiveSudden unexpected death in epilepsy (SUDEP) has been regarded as a leading cause of premature death in patients with epilepsy (PWE).
Yuanhang Pan   +12 more
doaj   +1 more source

Seizures, Cerebral Shutdown, and SUDEP [PDF]

open access: yesEpilepsy Currents, 2013
Several potential pathophysiologic phenomena, including “cerebral shutdown,” are postulated to be responsible for SUDEP. Since the evidence for a seizure-related mechanism is strong, a poor understanding of the physiology of human seizure termination is a major handicap.
Alireza Bozorgi, Samden D. Lhatoo
openaire   +3 more sources

Postictal serotonin levels are associated with peri-ictal apnea. [PDF]

open access: yes, 2019
ObjectiveTo determine the relationship between serum serotonin (5-HT) levels, ictal central apnea (ICA), and postconvulsive central apnea (PCCA) in epileptic seizures.MethodsWe prospectively evaluated video EEG, plethysmography, capillary oxygen ...
Bateman, Lisa M   +15 more
core   +2 more sources

The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]

open access: yes, 2020
Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco   +4 more
core   +1 more source

Noradrenergic pathway from the locus coeruleus to heart is implicated in modulating SUDEP

open access: yesiScience, 2023
Summary: Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among epilepsy patients. However, the underlying mechanism remains elusive.
XiTing Lian   +10 more
doaj   +1 more source

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