Results 91 to 100 of about 2,407,462 (283)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Hunger in America: Suffering We All Pay For [PDF]

open access: yes, 2011
Estimates the recession's impact on food insecurity and the national and state-by-state cost of hunger from hunger-induced illnesses, including depression; poor educational outcomes and reduced lifetime earnings, and private charity to help feed ...
Donald S. Shepard   +2 more
core  

What Does the Happy Life Require? Augustine on What the Summum Bonum Includes [PDF]

open access: yes, 2020
Many critics of religion insist that believing in a future life makes us less able to value our present activities and distracts us from accomplishing good in this world. In Augustine's case, this gets things backwards.
Cohoe, Caleb
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The Relationship between Neuroticism, Nightmare Characteristics and Suffering in respect to PTSD Psychopathology

open access: yesPrimenjena Psihologija
Introduction: The role of neuroticism in the relationship between nightmare characteristics (e.g., frequency and replicativity), and nightmare-related suffering, i.e., nightmare-related distress and impairment after awaking, is still to be explored ...
Sonja Protić   +3 more
doaj   +1 more source

Patient Suffering and the Anointing of the Sick [PDF]

open access: yes, 1992
Anthologized in On Moral Medicine: Theological Perspectives in Medical Ethics, 2nd edition. Edited by Stephen E. Lammers and Allen Verhey. Grand Rapids: Eerdmans, 1998, 356-364. And in On Moral Medicine: Theological Perspectives in Medical Ethics, 3rd
Lysaught, M. Therese
core   +1 more source

Not all suffering is pain: sources of patients' suffering in the emergency department call for improvements in communication from practitioners [PDF]

open access: yes, 2013
Background Provision of prompt, effective analgesia is rightly considered as a standard of care in the emergency department (ED). However, much suffering is not ‘painful’ and may be under-recognised. We sought to describe the burden of suffering in the
Bernard Foex   +15 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Consistent Vegetarianism and the Suffering of Wild Animals [PDF]

open access: yes, 2016
Ethical consequentialist vegetarians believe that farmed animals have lives that are worse than non-existence. In this paper, I sketch out an argument that wild animals have worse lives than farmed animals, and that consistent vegetarians should ...
Sittler-Adamczewski, Thomas M.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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