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What we need to know and do on sugammadex usage in pregnant and lactating women and those on hormonal contraceptives [PDF]
Anesthesia and Pain Medicine, 2023 Sugammadex is a chemically modified γ-cyclodextrin that is used as a selective reversal agent for steroidal neuromuscular blockade. The use of sugammadex has greatly increased globally; however, little is known about its potential adverse effects in ...
Wangseok Do, Ah-Reum Cho
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Anaphylaxis induced by sugammadex and sugammadex-rocuronium complex -a case report- [PDF]
Korean Journal of Anesthesiology, 2020 Background In sugammadex-induced anaphylaxis, sugammadex and/or sugammadex-rocuronium complex have possible allergenic epitope. Case We report a case of sugammadex-induced anaphylaxis during general anesthesia in a 60-year-old male undergoing orthopedic ...
Shu Chung Choi +3 more
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Frontiers in Pharmacology, 2023 Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg.
Sang-Hwan Ji +17 more
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Scientific Reports, 2023 Sugammadex reverses neuromuscular blockade by encapsulating steroidal neuromuscular blockers; therefore, it does not pharmacologically affect sedation levels.
Jeayoun Kim +6 more
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Effects of sugammadex on coagulation: a systematic review and meta-analysis [PDF]
BMC AnesthesiologyBackground Sugammadex, an innovative agent that rapidly and completely reverses rocuronium-induced neuromuscular blockade, may prolong coagulation time and influence postoperative bleeding.
Yu-Hsun Tsai +2 more
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Sugammadex-induced anaphylactic reaction: A systematic review
Journal of Anaesthesiology Clinical Pharmacology, 2022 Perioperative anaphylaxis is a rare, but life-threatening hypersensitivity reaction for patients undergoing surgical procedures. Sugammadex is a relatively new drug used to reverse the neuromuscular blockade of specific anesthetics in surgery.
Fatih Zecic +4 more
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Postoperative mortality in patients with end-stage renal disease according to the use of sugammadex: a single-center retrospective propensity score matched study [PDF]
Anesthesia and Pain Medicine, 2022 Background Clearance of the sugammadex-rocuronium complex is limited to renal excretion. There are restrictions on the use of sugammadex in patients with severe renal impairment.
Sanghoon Song +10 more
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Effects of rocuronium, sugammadex and rocuronium-sugammadex complex on coagulation in rats [PDF]
Revista Brasileira de Anestesiologia, 2021 Background and objectives: Sugammadex is an alternative pharmacological drug capable of reversing neuromuscular blockades without the limitations that are presented by anticholinesterase drugs.
Ismar Lima Cavalcanti +6 more
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Anesthesiology, 2023 Background: The dose of sugammadex recommended by the manufacturer for reversal of rocuronium is 2 mg/kg when the train-of-four count is 2 or more and 4 mg/kg when it is less than 2 but there is a posttetanic count of at least 1. The purpose of this dose-
T. Bowdle +5 more
semanticscholar +1 more source
Journal of Medical Case Reports, 2021 Background Sugammadex is a synthetic γ-cyclodextrin derivative designed to selectively bind to steroidal neuromuscular blocking agents and reverse their effects.
Tatsuo Horiuchi +6 more
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