Postoperative mortality in patients with end-stage renal disease according to the use of sugammadex: a single-center retrospective propensity score matched study [PDF]
Background Clearance of the sugammadex-rocuronium complex is limited to renal excretion. There are restrictions on the use of sugammadex in patients with severe renal impairment.
Sanghoon Song +10 more
doaj +1 more source
A Case of Respiratory Arrest After Lung Cancer Surgery due to Recurarization of Rocuronium Bromide. [PDF]
An 82‐year‐old male lung cancer patient experienced respiratory arrest after surgery due to recurarization of rocuronium bromide. Considering that many lung cancer patients are elderly and have numerous comorbidities, the risk of recurarization associated with muscle relaxants should always be considered.
Miura H, Miura J, Goto S, Yamamoto T.
europepmc +2 more sources
Effects of rocuronium, sugammadex and rocuronium-sugammadex complex on coagulation in rats [PDF]
Background and objectives: Sugammadex is an alternative pharmacological drug capable of reversing neuromuscular blockades without the limitations that are presented by anticholinesterase drugs.
Ismar Lima Cavalcanti +6 more
doaj +3 more sources
Anaphylaxis induced by sugammadex and sugammadex-rocuronium complex -a case report- [PDF]
Background In sugammadex-induced anaphylaxis, sugammadex and/or sugammadex-rocuronium complex have possible allergenic epitope. Case We report a case of sugammadex-induced anaphylaxis during general anesthesia in a 60-year-old male undergoing orthopedic ...
Shu Chung Choi +3 more
doaj +1 more source
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Cada, Dennis J +2 more
openaire +5 more sources
Sugammadex Vs. Neostigmine for Cerebral Perfusion During Emergence From General Anesthesia in Patients Undergoing Carotid Endarterectomy: A Double-Blind Randomized Controlled Trial. [PDF]
In this double‐blind RCT involving 82 patients undergoing carotid endarterectomy, sugammadex significantly reduced excessive cerebral blood flow during emergence from general anesthesia compared to neostigmine (MCAV% S: 24,600 vs. 31,575, p = 0.044). Sugammadex also shortened extubation time (110 vs.
Jia X +19 more
europepmc +2 more sources
What we need to know and do on sugammadex usage in pregnant and lactating women and those on hormonal contraceptives [PDF]
Sugammadex is a chemically modified γ-cyclodextrin that is used as a selective reversal agent for steroidal neuromuscular blockade. The use of sugammadex has greatly increased globally; however, little is known about its potential adverse effects in ...
Wangseok Do, Ah-Reum Cho
doaj +1 more source
Sugammadex is the first selective antagonist to reverse neuromuscular blockade induced by rocuronium and vecuronium. The mechanism by which sugammadex works is superior to current neuromuscular block reversal strategies in terms of speed, efficacy and side effects.
Dharshi, Karalapillai +2 more
+5 more sources
Background Sugammadex is a synthetic γ-cyclodextrin derivative designed to selectively bind to steroidal neuromuscular blocking agents and reverse their effects.
Tatsuo Horiuchi +6 more
doaj +1 more source
Sugammadex is a direct reversal agent of aminosteroid muscle relaxants, particularly rocuronium, with promptly and completely reverse of deep neuromuscular block (NMB), which allows better surgical conditions. Sugammadex exhibits advantages over indirect
Hsiao-Cheng Chang +4 more
doaj +1 more source

