Results 21 to 30 of about 9,823 (242)
Frontiers in Pharmacology, 2023 Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg.
Sang-Hwan Ji +17 more
doaj +1 more source
Clinical and Translational Science, 2023 Sugammadex, a selective antagonist of steroidal non‐depolarizing neuromuscular blocking agents, has been used in children in limited circumstances. However, neither pharmacokinetics (PKs) nor recovery profile of sugammadex for intense neuromuscular ...
Sang‐Hwan Ji +8 more
doaj +1 more source
Advantages and pitfalls of clinical application of sugammadex [PDF]
Anesthesia and Pain Medicine, 2020 Sugammadex, a modified γ-cyclodextrin, is one of the drugs focused on in the anesthetic field because it provides rapid and complete reversal from neuromuscular blockade (NMB) by encapsulating rocuronium.
Hyung Young Lee, Ki Tae Jung
doaj +1 more source
Rocuronium-sugammadex use for electroconvulsive therapy in a hemodialysis patient: a case report
JA Clinical Reports, 2016 Background Recently, rocuronium with subsequent use of sugammadex was proposed for electroconvulsive therapy (ECT) as an alternative to succinylcholine.
Shigeaki Kurita +5 more
doaj +1 more source
Profile of sugammadex for reversal of neuromuscular blockade in the elderly: Current perspectives [PDF]
, 2017 The number of elderly patients is increasing worldwide. This will have a significant impact on the practice of anesthesia in future decades. Anesthesiologists must provide care for an increasing number of elderly patients, who have an elevated risk of ...
Bertoncello, Francesco +2 more
core +1 more source
Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]
, 2012 Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape +46 more
core +1 more source
BMC Anesthesiology, 2023 Background Partial neuromuscular blockade (NMB) has been applied for some surgeries to reduce bleeding and prevent patient movement for spinal surgery.
Minyu Jian +8 more
doaj +1 more source
Reversal of Pipecuronium-Induced Moderate Neuromuscular Block with Sugammadex in the Presence of a Sevoflurane Anesthetic: A Randomized Trial [PDF]
, 2015 BACKGROUND: Pipecuronium is a steroidal neuromuscular blocking agent. Sugammadex, a relaxant binding [gamma]-cyclodextrin derivative, reverses the effect of rocuronium, vecuronium, and pancuronium.
Asztalos, László +5 more
core +1 more source
Sugammadex, a neuromuscular blockade reversal agent, causes neuronal apoptosis in primary cultures. [PDF]
, 2013 Sugammadex, a γ-cyclodextrin that encapsulates selectively steroidal neuromuscular blocking agents, such as rocuronium or vecuronium, has changed the face of clinical neuromuscular pharmacology.
Aguirre Rueda, Diana +10 more
core +2 more sources