Results 171 to 180 of about 627,249 (322)

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim   +9 more
wiley   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

Effectiveness of sugar taxation policies in Asia and Africa: a systematic review. [PDF]

open access: yesFront Oral Health
Fernandes MC   +6 more
europepmc   +1 more source

Self‐Doped and Biodegradable Glycosaminoglycan‐PEDOT Conductive Hydrogels Facilitate Electrical Pacing of iPSC‐Derived Cardiomyocytes

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.
The electrical properties and performance of conductive hydrogels based on sulfated‐glycosaminoglycan‐PEDOT (poly 3,4‐ethylenedioxythiophene) brush copolymers is studied, showing that the higher sulfation degree of heparin confers hydrogels with the highest conductivity.
Daniel Hachim   +11 more
wiley   +1 more source

A comparative study on enhanced enzymatic hydrolysis of diverse herbaceous and woody wastes by promising dilute acid and alkaline pretreatments. [PDF]

open access: yesBioresour Bioprocess
Shi R   +10 more
europepmc   +1 more source

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