Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Angewandte Chemie, EarlyView.We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu +18 more
wiley +2 more sources
Identification and Expression Analysis of Putative Sugar Transporter Gene Family during Bulb Formation in Lilies. [PDF]
Int J Mol SciHuang Z +10 more
europepmc +1 more source
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.Cyclopropene fatty acids have been made that allow the study of fatty acid uptake in complex mixtures of immune cells with single cell resolution and combined with metabolic and proteomic analysis so that for the first time nutrient uptake can be correlated to the phenotype of single immune cell.
Luuk Reinalda +14 more
wiley +2 more sources
Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations
Angewandte Chemie, EarlyView.Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera +2 more
wiley +2 more sources
A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells
Angewandte Chemie, EarlyView.A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim +7 more
wiley +2 more sources
Redirecting Excited‐State Proton Transfer Through Supramolecular Polymerization in Nanoconfinement
Angewandte Chemie, EarlyView.Supramolecular confinement redirects the excited‐state proton transfer pathway of an amphoteric emitter. In water, the molecule undergoes ESPD, whereas co‐assembly with γ‐cyclodextrin forms nanotubes that template slip‐stacked emitter pairs and enable ESIMPT. Structural and photophysical characterization of the assemblies shows that the preorganization
Luis C. Pantaleone +8 more
wiley +2 more sources
The Identification, Characterization, and Functional Analysis of the Sugar Transporter Gene Family of the Rice False Smut Pathogen, Villosiclava virens. [PDF]
Int J Mol SciQin H, Yin W, Luo C, Liu L.
europepmc +1 more source
Diurnal fluctuations in the content of soluble sugars and the expression of the TAI and LIN6 invertase genes and the STP1 sugar transporter gene in the leaves of the tomato (Solanum lycopersicum L.). [PDF]
Vavilovskii Zhurnal Genet SelektsiiFilyushin MA +2 more
europepmc +1 more source