Results 71 to 80 of about 1,176,128 (395)
Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy
Advanced Science, EarlyView.Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao +8 more
wiley +1 more source
A suicide prevention initiative at a jumping site: A mixed-methods evaluation
EClinicalMedicine, 2020 Background: Gap Park in Sydney, Australia has historically been recognised as a suicide jumping site. In 2010–2011 the Gap Park Masterplan initiative implemented a series of suicide prevention measures.
Victoria Ross, Yu Wen Koo, Kairi Kõlves
doaj +1 more source
Spirituality and Religiosity during Suicide Bereavement: A Qualitative Systematic Review
Religions, 2021 A loved one’s loss to suicide can be a traumatic experience and trigger a difficult grief process, identity changes, a loss of the sense of meaning and a spiritual crisis.
Austėja Agnietė Čepulienė +4 more
doaj +1 more source
Suicide Rates as They Vary by Region, Sexuality, and Gender [PDF]
, 2017 Suicide rates are not consistent worldwide. They vary in a wide variety of ways. Region, sexuality, and gender are all factors that influence suicide. This essay examines the manners in which region, sexuality, and gender influence suicide by themselves ...
Smith, Evan
core +2 more sources
Improving Nurses’ Attitudes, Beliefs, and Practices in Screening for Suicide Risk in Hospitalized Patients [PDF]
, 2020 Purpose: Forty-seven thousand Americans died from suicide in 2018. Providing nurses with facts about suicide, intervention methods, structured screening tools, and referral resources has been shown to change attitudes and increase screening rates.
Gibbs, Karen
core +1 more source
Advanced Science, EarlyView.Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang +16 more
wiley +1 more source
Suicide after contact with substance misuse services: a national registry study
BJPsych Open, 2020 BackgroundPeople with substance use disorders have a well-known increased risk for taking their own life. Previous research has mainly focused on suicide in mental health services, whereas there is limited knowledge regarding suicide after contact with ...
Martin Ø. Myhre +2 more
doaj +1 more source
Forecasting call and chat volumes at online helplines for mental health
BMC Public Health, 2023 Background Each year, many help seekers in need contact health helplines for mental support. It is crucial that they receive support immediately, and that waiting times are minimal. In order to minimize delay, helplines must have adequate staffing levels,
Tim Rens de Boer +4 more
doaj +1 more source
Advanced Science, EarlyView.Discover how Gram‐negative bacteria develop resistance to reactive oxygen species, and how scientists aim to overcome this challenge. Abstract Reactive oxygen species (ROS) are a promising alternative bactericide. However, it is questioned that bacteria can potentially develop resistance to ROS, similar to their resistance against antibiotics and ...
Congyang Mao +9 more
wiley +1 more source
Injury Epidemiology, 2023 Background Rates of firearm suicide have increased among women Veterans. Discussing firearm access and reducing access to lethal means of suicide when suicide risk is heightened are central tenets of suicide prevention, as is tailoring suicide prevention
Evan R. Polzer +8 more
doaj +1 more source