Results 101 to 110 of about 40,698 (218)

Prediction of Antibiotic Influence by Presence of Some β-lactamase Gene in AcinetobacterInfected Patients Hospitalized in Tehran, Iran [PDF]

Acinetobacter baumannii which is gram-negative rod and infecting hospitalized patient often develops multiple drug resistance patterns and causes serious problem in treatment.
آقابزرگی, سهراب, امانی, فیروز, اکبری, مهدی, دادگر پاکدل, جواد, دادگر پاکدل, فاطمه, رسولی, ایرج, نیاکان, محمد, کاظمی, سهیلا, یادگاری نیا, داوود   +8 more
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Optimizing Guideline-Recommended Antibiotic Doses for Pediatric Infective Endocarditis [PDF]

, 2016
The American Heart Association recently published an updated scientific statement on the management of infective endocarditis in childhood. The recommendations included for vancomycin, aminoglycoside, and β-lactam dosing and monitoring are based ...
Israel, Emily N., Knoderer, Chad A., Nichols, Kristen R., Thomas, Christopher A.   +3 more
core   +3 more sources

Flexible Development Programs for Antibacterial Drugs to Address Unmet Medical Needs

Emerging Infectious Diseases
The US Food and Drug Administration recognizes the unmet medical need for antibacterial drugs to treat serious bacterial diseases caused by resistant pathogens for which effective therapies are limited or lacking.
Mayurika Ghosh, Dmitri Iarikov, Xiaojing (Karen) Qi, Daniel Rubin, Simone Shurland, Avery Goodwin, Xiaohui Wei, Dakshina Chilukuri, Owen McMaster, Terry Miller, Peter Kim, Adam Sherwat   +11 more
doaj   +1 more source

Single-Dose Pharmacokinetics of Intravenous Sulbactam in Pediatric Patients [PDF]

, 2017
The pharmacokinetics of intravenously administered sulbactam were studied in 17 pediatric patients two to 14 years of age. Single doses of 12.5 or 25 mg/kg were infused over 3 min, and in previously healthy children, mean peak plasma concentrations 5 min
Guenin, Kathrin, Schaad, Urs B., Straehl, Peter   +2 more
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Effect of ampicillin-sulbactam on clinical capillary zone electrophoresis of serum proteins [PDF]

, 2017
Background: Capillary zone electrophoresis (CZE) is a well-accepted automated method used to separate serum proteins and detect monoclonal components. CZE uses ultraviolet detection at 214nm to directly quantify proteins via peptide bonds.
Möller, Helgard, Regeniter, Axel, Siede, Dominik, Siede, Werner H.   +3 more
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Dynamics of milk leukocytes in response to intramammary infusion of amoxicillin plus sulbactam during bovine subclinical mastitis

Veterinární Medicína, 2012
The therapeutic potential of amoxicillin plus sulbactam and its effect on dynamics of milk leukocytes in bovine sub clinical mastitis were investigated in this study.
U.K. De, R. Mukherjee
doaj   +1 more source

Efectividad in vitro de rifampicina, imipenem y sulbactam, en comparación con la antibioticoterapia convencional en infecciones por Acinetobacter baumannii y Pseudomonas aeruginosa en el Hospital Nacional San Rafael [PDF]

, 2017
El presente trabajo de investigación tuvo como objetivo evaluar la efectividad in vitro del esquema combinado de antibióticos compuesto por rifampicina, imipenem y sulbactam, en comparación con el esquema convencional de antimicrobianos, compuesto por ...
Martínez Mejía, Rodrigo Edgardo, Menjívar Guadrón, Marta Corina, Montoya Novoa, Armyda   +2 more
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ACINETOBACTER BAUMANNII: PREVALENCE, SPECTRUM AND DYNAMICS OF ANTIMICROBIAL RESISTANCE, SUSCEPTIBILITY TO ANTIBIOTIC COMBINATIONS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Objective. To study the spectrum and dynamics of antimicrobial resistance to Acinetobacter baumannii, to assess the resistance mechanisms to carbapenems and antibiotic combinations susceptibility. Material and Methods.
Tapalski D. V., Bonda N. A.
doaj   +1 more source

A Laboratory Protocol for Routine Therapeutic Drug Monitoring of Beta-Lactams Antimicrobials in Horses and Dogs

Antibiotics
Background: Although antibiotic resistance is a well-known issue in veterinary medicine, studies proposing real-time therapeutic monitoring (TDM) are lacking. The objective of the present study was to develop a simple and rapid protocol for the real-time
Anisa Bardhi, Aliai Lanci, Aurora Mannini, Carolina Castagnetti, Andrea Barbarossa   +4 more
doaj   +1 more source

Adverse Event Signals Associated with Beta-Lactamase Inhibitors: Disproportionality Analysis of USFDA Adverse Event Reporting System

Journal of Xenobiotics
Background: Beta-lactamase inhibitors (BLIs) are widely used with beta-lactam antibiotics to combat resistant infections, yet their safety profiles, especially for newer agents, remain underexplored.
Kannan Sridharan, Gowri Sivaramakrishnan
doaj   +1 more source