Results 91 to 100 of about 21,364 (252)

Prevalence of molecular markers of sulfadoxine–pyrimethamine and artemisinin resistance in Plasmodium falciparum from Pakistan

Malaria Journal, 2018
In Pakistan, artesunate (AS) in combination with sulfadoxine–pyrimethamine (SP) is the recommended treatment for uncomplicated Plasmodium falciparum malaria. Monitoring molecular markers of anti-malarial drug resistance is crucial for early detection and
A. Yaqoob, A. Khattak, M. Nadeem, Huma Fatima, Gillian Mbambo, A. Ouattara, Matthew Adams, N. Zeeshan, Shannon Takala-Harrison   +8 more
semanticscholar   +1 more source

Origin and evolution of sulfadoxine resistant Plasmodium falciparum.

PLoS Pathogens, 2010
The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa ...
Sumiti Vinayak, Md Tauqeer Alam, Tonya Mixson-Hayden, Andrea M McCollum, Rithy Sem, Naman K Shah, Pharath Lim, Sinuon Muth, William O Rogers, Thierry Fandeur, John W Barnwell, Ananias A Escalante, Chansuda Wongsrichanalai, Frederick Ariey, Steven R Meshnick, Venkatachalam Udhayakumar   +15 more
doaj   +1 more source

Five years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll out. [PDF]

PLoS ONE, 2011
Antimalarial drug resistance is a major obstacle to malaria control and eventual elimination. The routine surveillance for molecular marker of resistance is an efficient way to assess drug efficacy, which remains feasible in areas where malaria control ...
Jaishree Raman, Katya Mauff, Pedro Muianga, Abdul Mussa, Rajendra Maharaj, Karen I Barnes   +5 more
doaj   +1 more source

The Prevalence of Malaria Among Pregnant Women at a Tertiary Care Hospital in Somalia: A Cross‐Sectional Study

BioMed Research International, Volume 2025, Issue 1, 2025.
Background: In countries like Somalia, where health infrastructure is inadequate and malaria is endemic, immunosuppression during pregnancy increases the risk of placental malaria; this, in turn, leads to anemia, low birth weight, preterm delivery, and stillbirth, causing severe complications that pose a life‐threatening risk to both the mother and ...
Said Mohamed Mohamud, Serpil Doğan, Ahmed Issak Hussein, Rahma Yusuf Haji Mohamud, Zerife Orhan, Adem Doğaner, Baisakhi Banerjee   +6 more
wiley   +1 more source

Sulfadoxine-Pyrimethamine Exhibits Dose-Response Protection Against Adverse Birth Outcomes Related to Malaria and Sexually Transmitted and Reproductive Tract Infections

Clinical Infectious Diseases, 2017
Summary Compared to 0–1 dose of intermittent preventive treatment of malaria using sulfadoxine-pyrimethamine, ≥2 doses protects pregnant women against adverse birth outcomes attributable to malaria infection and to curable sexually transmitted and ...
R. Chico, E. B. Chaponda, E. B. Chaponda, C. Ariti, D. Chandramohan   +4 more
semanticscholar   +1 more source

Evidence of triple mutant Pfdhps ISGNGA haplotype in Plasmodium falciparum isolates from North-east India: An analysis of sulfadoxine resistant haplotype selection

Genomics Data, 2016
Background: North-east region of India has consistent role in the spread of multi drug resistant Plasmodium (P.) falciparum to other parts of Southeast Asia.
Manuj K. Das, Sumi Chetry, Mohan C. Kalita, Prafulla Dutta   +3 more
doaj   +1 more source

A LC‐MS/MS Assay for Quantification of Amodiaquine and Desethylamodiaquine in Dried Blood Spots on Filter Paper

International Journal of Analytical Chemistry, Volume 2025, Issue 1, 2025.
Artesunate–amodiaquine (ARS–AQ) is a first‐line antimalarial treatment recommended by the World Health Organization. AQ is the long acting partner drug in this combination, and therapeutic success is correlated with the terminal exposure to AQ. Dried blood spot (DBS) sampling for AQ is a convenient and minimally invasive technique, especially suitable ...
Natpapat Kaewkhao, Joel Tarning, Daniel Blessborn, Daipayan Roy   +3 more
wiley   +1 more source

Intermittent preventive treatment of malaria in pregnancy: a cross-sectional survey to assess uptake of the new sulfadoxine–pyrimethamine five dose policy in Ghana

Malaria Journal, 2017
Malaria in pregnancy poses a great risk to both mother and fetus. In Ghana, malaria accounts for 3.4% of deaths and 16.8% of all hospital admissions in pregnant women.
I. Owusu-Boateng, F. Anto
semanticscholar   +1 more source

Review of pyronaridine anti-malarial properties and product characteristics. [PDF]

, 2012
Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J, Borghini-Fuhrer, Isabelle, Craft, J Carl, Croft, Simon L, Duparc, Stephan, Fleckenstein, Lawrence, Rim, Han-Jong, Shin, Chang-Sik   +7 more
core   +2 more sources

Nanoformulation and Preclinical Evaluation of Dihydroartemisinin–Lumefantrine and Primaquine as Combined Antimalarial Therapy

Journal of Nanotechnology, Volume 2025, Issue 1, 2025.
The World Health Organization recommends artemisinin‐based combinations for uncomplicated malaria treatment. Artemether and lumefantrine (LUM) are the first‐line treatments, with artemether serving as a prodrug of dihydroartemisinin (DHA), while primaquine (PQ) is primarily used as a prophylactic drug.
Pesila Odera, Geoffrey Otieno, Joab Onyango, Bernhards Ogutu, James Owour, Florence Oloo, Martin Ongas, Hulda Swai, Jeremiah Gathirwa, Arnab Biswas   +9 more
wiley   +1 more source