Results 121 to 130 of about 21,364 (252)

Care-seeking patterns for fatal malaria in Tanzania. [PDF]

open access: yes, 2004
BACKGROUND\ud \ud Once malaria occurs, deaths can be prevented by prompt treatment with relatively affordable and efficacious drugs. Yet this goal is elusive in Africa.
de Savigny, Don   +8 more
core   +4 more sources

Surveillance for sulfadoxine-pyrimethamine resistant malaria parasites in the Lake and Southern Zones, Tanzania, using pooling and next-generation sequencing

open access: yesMalaria Journal, 2017
BackgroundMalaria in pregnancy (MiP) remains a major public health challenge in areas of high malaria transmission. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended to prevent the adverse ...
Jeremiah Ngondi   +16 more
semanticscholar   +1 more source

Atovaquone and proguanil hydrochloride compared with chloroquine or pyrimethamine/sulfadoxine for treatment of acute Plasmodium falciparum malaria in Peru

open access: yesBrazilian Journal of Infectious Diseases
The efficacy and safety of a fixed-dose combination of atovaquone and proguanil hydrochloride (MalaroneTM) were compared with chloroquine or pyrimethamine/sulfadoxine in patients with acute falciparum malaria in northern Peru.
A. Llanos-Cuentas   +4 more
doaj   +1 more source

Antimalarial Drug Resistance: A Brief History of Its Spread in Indonesia

open access: yesDrug Design, Development and Therapy, 2023
Loeki Enggar Fitri,1,2 Aulia Rahmi Pawestri,1,2 Nuning Winaris,1,2 Agustina Tri Endharti,1 Alif Raudhah Husnul Khotimah,3,4 Hafshah Yasmina Abidah,3,4 John Thomas Rayhan Huwae3,5 1Department of Parasitology Faculty of Medicine, Universitas Brawijaya ...
Fitri LE   +6 more
doaj  

Therapeutic Efficacy of Sulfadoxine-Pyrimethamine and Prevalence of Resistance Markers in Tanzania Prior to Revision of Malaria Treatment Policy: Plasmodium Falciparum Dihydrofolate Reductase and Dihydropteroate Synthase Mutations in Monitoring in Vivo Resistance. [PDF]

open access: yes, 2004
Prior to the 2001 malarial treatment policy change in Tanzania, we conducted trials to assess the efficacy of sulfadoxine-pyrimethamine (SP) and the usefulness of molecular markers in monitoring resistance.
Abdulla, Salim   +10 more
core   +1 more source

Audit of failure rate of sulfadoxine/pyrimetham combined with chloroquine to treat falciparum malaria at single fourteen-day follow-up

open access: yesSouth African Family Practice, 2002
Objective: To assess the failure rate of the present first line treatment regime for uncomplicated falciparum malaria of sulfadoxine/pyrimethamine combined with chloroquine. Design: A before-after study. Setting: Ndumo Clinic, Ingwavuma District, South
C.H. Vaughan Williams   +3 more
doaj   +1 more source

Requirements for Diagnosis of Malaria at Different Levels of the Laboratory Network in Africa. [PDF]

open access: yes, 2009
The rapid increase of resistance to cheap, reliable antimalarials, the increasing cost of effective drugs, and the low specificity of clinical diagnosis has increased the need for more reliable diagnostic methods for malaria.
Barnish   +5 more
core   +1 more source

Differential infectivity of gametocytes after artemisinin-based combination therapy of uncomplicated falciparum malaria

open access: yesAfrican Journal of Laboratory Medicine, 2018
Background: Most malaria-endemic countries use artemisinin-based combination therapy (ACT) as their first-line treatment. ACTs are known to be highly effective on asexual stages of the malaria parasite.
Dinkorma T. Ouologuem   +13 more
doaj   +1 more source

Recent uptake of intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine is associated with increased prevalence of Pfdhfr mutations in Bobo-Dioulasso, Burkina Faso

open access: yesMalaria Journal, 2017
BackgroundThe impact of sulfadoxine–pyrimethamine (SP) used as intermittent preventive treatment during pregnancy (IPTp-SP) on mutant parasite selection has been poorly documented in Burkina Faso.
M. Cisse   +5 more
semanticscholar   +1 more source

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