Results 121 to 130 of about 20,006 (291)

Intermittent screening and treatment with artemether–lumefantrine versus intermittent preventive treatment with sulfadoxine–pyrimethamine for malaria in pregnancy: a facility-based, open-label, non-inferiority trial in Nigeria

Malaria Journal, 2018
The spread of SP resistance may compromise the effectiveness of intermittent preventive treatment of malaria in pregnancy (MiP) with sulfadoxine–pyrimethamine (IPTp-SP) across Africa.
Ekpereonne B. Esu, N. Berens-Riha, M. Pritsch, N. Nwachuku, T. Loescher, M. Meremikwu   +5 more
semanticscholar   +1 more source

S3‐Leitlinie: Diagnostik und Therapie der epidermalen Nekrolyse (Stevens‐Johnson‐Syndrom und toxisch epidermale Nekrolyse) – Teil 1: Diagnostik, initiales Management und immunmodulierende Systemtherapie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 10, Page 1448-1467, October 2024.
Zusammenfassung Das Stevens‐Johnson‐Syndrom und die toxisch epidermale Nekrolyse (SJS/TEN) sind seltene, in erster Linie arzneimittelinduzierte, akut lebensbedrohliche Erkrankungen der Haut und Schleimhäute. Sie werden heute als Varianten einer Krankheitsentität mit unterschiedlichem Schweregrad betrachtet, die als epidermale Nekrolyse (EN) bezeichnet ...
Ruben Heuer, Maren Paulmann, Thorsten Annecke, Björn Behr, Katharina Boch, Anja M. Boos, Knut Brockow, Lars E. French, Jochen Gille, Verena Gundlach, Bernd Hartmann, Peter Höger, Silke C. Hofmann, Tobias Klein, Marcus Lehnhardt, Yvonne Liß, Philip Maier, Philipp Mandel, Nicos Marathovouniotis, Finnja Marlok, Hans Mittelviefhaus, Uwe Pleyer, Marie Pradeau, Katharina Rall, Siegbert Rieg, Heike Rittner, Frank Sander, Stefan Schnitzler, Christina Schut, Annette Stolle, Artem Vorobyev, Bettina Wedi, Johannes Weiss, Maximilian Zepp, Mirjana Ziemer, Maja Mockenhaupt, Alexander Nast   +36 more
wiley   +1 more source

Scheduled Intermittent Screening with Rapid Diagnostic Tests and Treatment with Dihydroartemisinin-Piperaquine versus Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine for Malaria in Pregnancy in Malawi: An Open-Label Randomized Controlled Trial

PLoS Medicine, 2016
Background In Africa, most plasmodium infections during pregnancy remain asymptomatic, yet are associated with maternal anemia and low birthweight.
M. Madanitsa, L. Kalilani, V. Mwapasa, A. V. van Eijk, Carole Khairallah, Doreen Ali, Cheryl Pace, James Smedley, K. Thwai, Brandt Levitt, Duolao Wang, A. Kang’ombe, B. Faragher, S. Taylor, S. Meshnick, F. T. ter Kuile   +15 more
semanticscholar   +1 more source

The Effect of Malaria on Responses to Unrelated Vaccines in Animals and Humans: A Systematic Review and Meta‐Analysis

Parasite Immunology, Volume 46, Issue 10, October 2024.
ABSTRACT Vaccine efficacy varies globally, often showing reduced immune responses in low‐ and middle‐income countries, possibly due to the immunomodulatory effects of parasitic infections like malaria. This systematic review evaluates the impact of malaria on immune responses to unrelated vaccines in humans and animals.
Ludoviko Zirimenya, Agnes Natukunda, Jacent Nassuuna, Joyce Kabagenyi, Gyaviira Nkurunungi, Alison M. Elliott, Emily L. Webb   +6 more
wiley   +1 more source

Molecular Evidence for Plasmodium falciparum Resistance to Sulfadoxine-Pyrimethamine but Absence of K13 Mutations in Mangaluru, Southwestern India.

American Journal of Tropical Medicine and Hygiene, 2018
In most of India, sulfadoxine-pyrimethamine (SP) plus artesunate serves as first-line treatment for uncomplicated falciparum malaria. In 112 clinical Plasmodium falciparum isolates from Mangaluru, southwestern India, we sequenced molecular markers ...
J. Wedam, Costanza Tacoli, Prabhanjan P. Gai, Konrad Siegert, S. Kulkarni, Rashmi Rasalkar, A. Boloor, A. Jain, C. Mahabala, Shantaram B. Baliga, Damodara Shenoy, Rajeshwari Devi, P. Gai, F. Mockenhaupt   +13 more
semanticscholar   +1 more source

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial. [PDF]

, 2018
BACKGROUND: Primaquine and methylene blue are gametocytocidal compounds that could prevent Plasmodium falciparum transmission to mosquitoes. We aimed to assess the efficacy and safety of primaquine and methylene blue in preventing human to mosquito ...
Bousema, Teun, Bradley, John, Brown, Joelle M, Chen, Ingrid, Diarra, Kalifa, Diawara, Halimatou, Dicko, Alassane, Drakeley, Chris, Gosling, Roly, Hwang, Jimee, Issiaka, Djibrilla, Keita, Sekouba, Kone, Daouda T, Lanke, Kjerstin, Mahamar, Almahamoudou, McCulloch, Charles, Müller, Olaf, Roh, Michelle E, Sanogo, Koualy, Soumare, Harouna M, Srinivasan, Vinay, Stone, Will JR, Traore, Sekou F   +22 more
core   +2 more sources

Safety of Seasonal Malaria Chemoprevention (SMC) with Sulfadoxine-Pyrimethamine plus Amodiaquine when Delivered to Children under 10 Years of Age by District Health Services in Senegal: Results from a Stepped-Wedge Cluster Randomized Trial

PLoS ONE, 2016
Background It is recommended that children aged 3 months to five years of age living in areas of seasonal transmission in the sub-Sahel should receive Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ) during ...
J. Ndiaye, B. Cissé, E. Ba, J. Gomis, C. Ndour, J. Molez, F. Fall, C. Sokhna, B. Faye, E. Kouevijdin, F. K. Niane, M. Cairns, J. Trape, C. Rogier, O. Gaye, B. Greenwood, P. Milligan   +16 more
semanticscholar   +1 more source

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Chandramohan, Daniel, Cousens, Simon, Diallo, Diadier A, Diarra, Amidou, Gansané, Adama, Greenwood, Brian, Kaboré, Youssouf, Kangoyé, David T, Konaté, Amadou T, Milligan, Paul J, Ouédraogo, Alphonse, Ouédraogo, Amidou Z, Ouédraogo, Espérance, Ouédraogo, Issa N, Sirima, Sodiomon B, Soulama, Issiaka, Tiono, Alfred B, Yaro, Jean Baptiste   +17 more
core   +2 more sources

Surveillance for sulfadoxine-pyrimethamine resistant malaria parasites in the Lake and Southern Zones, Tanzania, using pooling and next-generation sequencing

Malaria Journal, 2017
BackgroundMalaria in pregnancy (MiP) remains a major public health challenge in areas of high malaria transmission. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended to prevent the adverse ...
Jeremiah Ngondi, D. Ishengoma, Stephanie M. Doctor, K. Thwai, Corinna Keeler, S. Mkude, O. Munishi, R. Willilo, S. Lalji, Naomi Kaspar, C. Kitojo, L. Paxton, Nicholas J Hathaway, J. Bailey, J. Juliano, S. Meshnick, J. Gutman   +16 more
semanticscholar   +1 more source

A Molecular Surveillance System for Global Patterns of Drug Resistance in Imported Malaria

Emerging Infectious Diseases, 2003
Analysis of imported malaria in travelers may represent a novel surveillance system for drug-resistant malaria. We analyzed consecutive falciparum malaria isolates from Canadian travelers from 1994 to 2000, for polymorphisms in pfcrt, dhfr, and dhps ...
Annie-Claude Labbé, Samir N. Patel, Ian Crandall, Kevin C. Kain   +3 more
doaj   +1 more source