Results 1 to 10 of about 36,452 (164)

Burkholderia pseudomallei in Sarawak, Malaysian Borneo, Remains Highly Susceptible to Trimethoprim-Sulfamethoxazole Despite Resistance to Its Individual Components [PDF]

Pathogens
Burkholderia pseudomallei, the causative agent of melioidosis, is endemic in Sarawak, Malaysian Borneo, where it is represented by a unique gentamicin-susceptible population. Despite trimethoprim-sulfamethoxazole (co-trimoxazole) being the cornerstone of
Liana Lantong Sumbu, Tonnii Loong-Loong Sia, Mong-How Ooi, Anand Mohan, Jin-Shyan Wong, Yuwana Podin   +5 more
doaj   +2 more sources

Comparative evaluation of trimethoprim-sulfonamide ratios and synergistic interactions against porcine respiratory pathogens [PDF]

Frontiers in Veterinary Science
IntroductionPotentiated sulfonamides are widely used in the treatment of porcine respiratory disease complex, but their synergistic activity depends on pathogen-related and pharmacodynamic factors, including the trimethoprim-to-sulfonamide ratio.
Patrik Mag, Patrik Mag, Ulrich Klein, Wouter Depondt, Imre Sándor Piross, Imre Sándor Piross, Réka Tóth, Zoltán Somogyi, Dóra Kovács, Dóra Kovács, Ádám Kerek, Ádám Kerek, Ákos Jerzsele, Ákos Jerzsele   +13 more
doaj   +2 more sources

Case Report: Pulmonary nocardiosis: three case reports and literature review [PDF]

Frontiers in Medicine
Pulmonary nocardiosis is a relatively uncommon opportunistic infection characterized by nonspecific clinical features, often leading to delays in diagnosis and treatment.
Qi Zhao, Min Wang, Xincheng Nie, LIna Fu, Xuehao Fu   +4 more
doaj   +2 more sources

Dose Optimization of Aditoprim-Sulfamethoxazole Combinations Against Trueperella pyogenes From Patients With Clinical Endometritis by Using Semi-mechanistic PK/PD Model

Frontiers in Pharmacology, 2021
Combinations of two and more drugs with different target sites are being used as a new treatment regimen for resistant clones of bacteria. Though, achieving the right combination of the drugs for optimal dosage regimen is challenging.
Muhammad Kashif Maan, Muhammad Kashif Maan, Tamoor Hamid Chaudhry, Adeel Sattar, Muhammad Abu Bakr Shabbir, Saeed Ahmed, Kun Mi, Waqas Ahmed, Shuyu Xie, Li Xin, Lingli Huang, Lingli Huang   +11 more
doaj   +1 more source

Clinical manifestations and antimicrobial susceptibility of Nocardia species at a tertiary hospital in Taiwan, 2011–2020

Journal of the Formosan Medical Association, 2022
Background: The study aimed to assess the clinical characteristics of patients with nocardiosis, to evaluate the in vitro susceptibility of antimicrobial agents against Nocardia species, and to explore changes in antimicrobial susceptibilities in this ...
Chong Kei Lao, Mei-Chueh Tseng, Cheng-Hsun Chiu, Nan-Yu Chen, Chih-Hung Chen, Wen-Hung Chung, Tsui-Ping Liu, Jang-Jih Lu, Hsin-Chih Lai, Lan-Yan Yang, Chia-Hui Lee, Ting-Shu Wu   +11 more
doaj   +1 more source

Multisensory Systems Based on Perfluorosulfonic Acid Membranes Modified with Functionalized CNTs for Determination of Sulfamethoxazole and Trimethoprim in Pharmaceuticals

Membranes, 2022
Sulfamethoxazole and trimethoprim are synthetic bacteriostatic drugs. A potentiometric multisensory system for the analysis of sulfamethoxazole and trimethoprim combination drugs was developed.
Anna Parshina, Anastasia Yelnikova, Ekaterina Safronova, Tatyana Kolganova, Victoria Kuleshova, Olga Bobreshova, Andrey Yaroslavtsev   +6 more
doaj   +1 more source

Case Report: Disseminated Nocardiosis Caused by Nocardia vulneris in a Patient With Macroglobulinemia

Frontiers in Public Health, 2022
This report describes a case of disseminated nocardiosis, caused by Nocardia vulneris, in a 61-year-old man with macroglobulinemia and presenting with repeated fever, cough, shortness of breath, and muscle pain. The isolated Nocardia strain was resistant
Fulan Qiu, Zhiyi Ma, Rongrong Zhong, Haonan Huang, Yuehua Wang, Hui Liu   +5 more
doaj   +1 more source

The Inhibitory Effect of Adenylic Acid on the Bitterness of the Antibacterial Combination Drug Trimethoprim/Sulfamethoxazole

Chemical and Pharmaceutical Bulletin, 2023
The purpose of the present study was to evaluate bitterness suppression effect of adenylic acid (AMP) as a nucleotide-derived nutrient enhancer on a bitter commercial drug. In the present study, we evaluated peripheral bitterness inhibition effect of AMP on the trimethoprim (TMP) and sulfamethoxazole (SMZ) combination formulation based on taste sensor.
Jun, Kawahara, Miyako, Yoshida, Honami, Kojima, Rio, Uno, Minoru, Ozeki, Ikuo, Kawasaki, Masaaki, Habara, Hidekazu, Ikezaki, Takahiro, Uchida   +8 more
openaire   +2 more sources

Manifestations and Management of Trimethoprim/Sulfamethoxazole–Resistant Nocardia otitidiscaviarum Infection

Emerging Infectious Diseases, 2023
Nocardia can cause systemic infections with varying manifestations. Resistance patterns vary by species. We describe N. otitidiscavarium infection with pulmonary and cutaneous manifestations in a man in the United States. He received multidrug treatment
Katherine Fu, Kyle White, Aliaksandr Ramaniuk, Vidya Kollu, Daniel Urbine   +4 more
doaj   +1 more source

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat. [PDF]

, 2016
Case summaryA domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs.
Keel, M Kevin, Reagan, Krystle L, Sykes, Jane E, Vishkautsan, Polina   +3 more
core   +4 more sources