Results 21 to 30 of about 372,261 (217)

Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules [PDF]

Biomolecules, 2021
Hydrogen sulfide and its oxidation products are involved in many biological processes, and sulfane sulfur compounds, which contain sulfur atoms bonded to other sulfur atom(s), as found in hydropersulfides (R-S-SH), polysulfides (R-S-Sn-S-R), hydrogen ...
Honami Echizen, Eita Sasaki, Kenjiro Hanaoka   +2 more
doaj   +3 more sources

Mitochondrial dysfunction-driven AMPK-p53 axis activation underpins the anti-hepatocellular carcinoma effects of sulfane sulfur [PDF]

Scientific Reports
Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, notoriously refractory to conventional chemotherapy. Historically, sulfane sulfur-based compounds have been explored for the treatment of HCC, but their efficacy has been ...
Xue Zheng, Yuhua Luo, Rui Huo, Yiwen Wang, Youbang Chen, Mianrong Chen, Qi Zhao, Kexin Li, Hanyi Zhang, Xiaotong Li, Xiang Li, Hui Zhang, Zaopeng He, Li Huang, Chun-tao Yang   +14 more
doaj   +3 more sources

2H-Thiopyran-2-thione sulfine, a compound for converting H2S to HSOH/H2S2 and increasing intracellular sulfane sulfur levels [PDF]

Nature Communications
Reactive sulfane sulfur species such as persulfides (RSSH) and H2S2 are important redox regulators and closely linked to H2S signaling. However, the study of these species is still challenging due to their instability, high reactivity, and the lack of ...
Qi Cui, Meg Shieh, Tony W. Pan, Akiyuki Nishimura, Tetsuro Matsunaga, Shane S. Kelly, Shi Xu, Minkyung Jung, Seiryo Ogata, Masanobu Morita, Jun Yoshitake, Xiaoyan Chen, Jerome R. Robinson, Wei-Jun Qian, Motohiro Nishida, Takaaki Akaike, Ming Xian   +16 more
doaj   +3 more sources

Metabolic Reprogramming of Sulfur in Hepatocellular Carcinoma and Sulfane Sulfur-Triggered Anti-Cancer Strategy [PDF]

Frontiers in Pharmacology, 2020
Metabolic reprogramming is a cancer hallmark. Although the reprogramming of central carbon has been well documented, the role of sulfur metabolism has been largely overlooked.
Ximing Zhang, Mianrong Chen, Xiang Ni, Yingying Wang, Xue Zheng, Hui Zhang, Shi Xu, Chun-tao Yang   +7 more
doaj   +5 more sources

The glial Gomori-positive material is sulfane sulpfur. [PDF]

Folia Histochemica et Cytobiologica, 2008
The Gomori-positive glia are periventricular astrocytes with abundant cytoplasmic granular material, predominantly occupying a periventricular site in the brain.
Marta Góralska, Piotr Sura, Małgorzata Iciek, Zbigniew Srebro   +3 more
doaj   +6 more sources

Orthogonal Persulfide Generation through Precision Tools Provides Insights into Mitochondrial Sulfane Sulfur [PDF]

Angewandte Chemie International Edition
The sulfane sulfur pool, comprised of persulfide (RS-SH) and polysulfide (RS-SnH) derived from hydrogen sulfide (H2S), has emerged as a major player in redox biochemistry. Mitochondria, besides energy generation, serve as significant cellular redox hubs,
Suman Manna, Ragini Agrawal, Tarun Yadav, T. Anand Kumar, Pooja Kumari, Aadishakti Dalai, Shaunak Kanade, Nagaraj Balasubramanian, Amit Singh, Harinath Chakrapani   +9 more
semanticscholar   +5 more sources

Transcription factor OxyR regulates sulfane sulfur removal and L-cysteine biosynthesis in Corynebacterium glutamicum. [PDF]

Appl Environ Microbiol, 2023
Sulfane sulfur, a collective term for hydrogen polysulfide and organic persulfide, often damages cells at high concentrations. Cells can regulate intracellular sulfane sulfur levels through specific mechanisms, but these mechanisms are unclear in ...
Du H, Qi Y, Qiao J, Li L, Wei L, Xu N, Shao L, Liu J.   +7 more
europepmc   +2 more sources

Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology [PDF]

Molecules, 2014
The understanding of sulfur bonding is undergoing change. Old theories on hypervalency of sulfur and the nature of the chalcogen-chalcogen bond are now questioned.
John I. Toohey, Arthur J. L. Cooper
doaj   +5 more sources

Modified cyclodextrins solubilize elemental sulfur in water and enable biological sulfane sulfur delivery. [PDF]

Chem Sci, 2020
An important form of biological sulfur is sulfane sulfur, or S0, which is found in polysulfide and persulfide compounds as well as in elemental sulfur. Sulfane sulfur, often in the form of S8, functions as a key energy source in the metabolic processes of thermophilic Archaean organisms found in sulfur-rich environments and can be metabolized both ...
Bolton SG, Pluth MD.
europepmc   +5 more sources

The Transcriptional Repressor PerR Senses Sulfane Sulfur by Cysteine Persulfidation at the Structural Zn²⁺ Site in Synechococcus sp. PCC7002. [PDF]

Antioxidants (Basel), 2023
Cyanobacteria can perform both anoxygenic and oxygenic photosynthesis, a characteristic which ensured that these organisms were crucial in the evolution of the early Earth and the biosphere.
Liu D, Song H, Li Y, Huang R, Liu H, Tang K, Jiao N, Liu J.   +7 more
europepmc   +2 more sources