Results 61 to 70 of about 1,751 (145)
Hydrogen sulfide (H2S) is the most recently established gaseous vasodilator, enzymatically produced from cysteine metabolism, involved in a number of pathophysiological processes.
Evgeniya Anishchenko +5 more
doaj +1 more source
Sulfane Sulfur in Toxicology: A Novel Defense System Against Electrophilic Stress
Electrophiles can undergo covalent modification of cellular proteins associated with its dysfunction, thereby exerting toxicity. Small nucleophilic molecules such as glutathione protect cells from electrophilic insult by binding covalently to electrophiles to form adducts that are excreted into the extracellular space.
Yasuhiro, Shinkai, Yoshito, Kumagai
openaire +2 more sources
Is Development of High-Grade Gliomas Sulfur-Dependent?
We characterized γ-cystathionase, rhodanese and 3-mercaptopyruvate sulfurtransferase activities in various regions of human brain (the cortex, thalamus, hypothalamus, hippocampus, cerebellum and subcortical nuclei) and human gliomas with II to IV grade ...
Maria Wróbel +5 more
doaj +1 more source
Supersulfide biology and translational medicine for disease control
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source
Intermediates in the Sox sulfur oxidation pathway are bound to a sulfane conjugate of the carrier protein SoxYZ. [PDF]
The Sox pathway found in many sulfur bacteria oxidizes thiosulfate to sulfate. Pathway intermediates are covalently bound to a cysteine residue in the carrier protein SoxYZ.
Daniel B Grabarczyk, Ben C Berks
doaj +1 more source
3-Mercaptopyruvate sulfurtransferase: an enzyme at the crossroads of sulfane sulfur trafficking
Abstract 3-Mercaptopyruvate sulfurtransferase (MPST) catalyzes the desulfuration of 3-mercaptopyruvate to generate an enzyme-bound hydropersulfide. Subsequently, MPST transfers the persulfide’s outer sulfur atom to proteins or small molecule acceptors. MPST activity is known to be involved in hydrogen sulfide generation, tRNA thiolation,
Brandán Pedre, Tobias P. Dick
openaire +2 more sources
A nickel catalyzed electrochemical cross‐electrophile coupling approach for the base‐free synthesis of (un)symmetric (hetero)aryl and alkyl sulfides from organic halides and disulfides is described. The reaction is broadly applicable and tolerates water and air atmosphere. A formal cross‐electrophile coupling approach enables the base‐free synthesis of
Jona Queder, Gerhard Hilt
wiley +1 more source
Hydrogen sulfide (H2S) is a gasotransmitter that regulates cellular homeostasis and impacts on multiple physiological and pathophysiological processes. However, it exerts many of its biological actions indirectly via the formation of H2S-derived sulfane ...
Sofia-Iris Bibli +8 more
doaj +1 more source
We developed a reversible fluorescent probe for sulfane sulfur. This probe enabled us to monitor concentration changes of sulfane sulfur.
Yoko Takano +9 more
openaire +3 more sources
ABSTRACT Garlic quality is attributed to a diverse array of volatile and non‐volatile compounds, and several varieties are protected under geographical indication schemes, whereas many typical local cultivars remain chemically uncharacterized. Among them, white garlic from Piacenza (Italy) is a traditional product with recognized sensory attributes. In
Giulia Leni +7 more
wiley +1 more source

