Results 41 to 50 of about 22,581 (252)

Forward chemical genetic screens in Arabidopsis identify genes that influence sensitivity to the phytotoxic compound sulfamethoxazole

BMC Plant Biology, 2012
Background The sulfanilamide family comprises a clinically important group of antimicrobial compounds which also display bioactivity in plants. While there is evidence that sulfanilamides inhibit folate biosynthesis in both bacteria and plants, the ...
Schreiber Karl J, Austin Ryan S, Gong Yunchen, Zhang Jianfeng, Fung Pauline, Wang Pauline W, Guttman David S, Desveaux Darrell   +7 more
doaj   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He, Alyssa Costello, Yanjie Liu, Weicheng Wang, Zhichang Zhang, Quanjun Cui, Xinlin Yang   +6 more
wiley   +1 more source

Photosynthesis of NH3 from NO3− Using CH4 in Homogenous Rhenium Catalysis

Angewandte Chemie, Volume 137, Issue 25, June 17, 2025.
We present a Re catalysis of one‐pot synthesis of NH3 from NO3− using CH4 as a reductant under UV light irradiation. We are able to directly convert NO3−, leading to several environmental issues, to NH3, an essential compound as a fertilizer and industrial raw material, by means of CH4, which has a high affinity with renewable resource/energy, as a ...
Genta Nakamura, Masaya Sakurai, Yohei Kametani, Yudai Kawasaki, Yoshihito Shiota, Kazunari Yoshizawa, Seiji Ogo, Takahiro Matsumoto   +7 more
wiley   +2 more sources

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk, Neslihan Balci, Osman Nuri Aslan, Erbay Kalay   +3 more
wiley   +1 more source

Sulfanilamide in solution and liposome vesicles; in vitro release and UV-stability studies

Saudi Pharmaceutical Journal, 2017
The main goal of this study was to develop a liposome formulation with sulfanilamide and to investigate the liposomes impact on its release and stability to the UV-A/UV-B and UV-C irradiation.
Sanja Petrović, Ana Tačić, Saša Savić, Vesna Nikolić, Ljubiša Nikolić, Sanela Savić   +5 more
doaj  

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen, Oguz Özbek, Meryem Topal, Hatice Şahin, Ümit M. Koçyiğit   +4 more
wiley   +1 more source

Acidosis potentiates endothelium-dependent vasorelaxation and gap junction communication in the superior mesenteric artery. [PDF]

, 2018
Extracellular pH is an important physiological determinant of vascular tone that is normally maintained within 7.35-7.45. Any change outside this range leads to severe pathological repercussions.
Mohanty, Ipsita, Parija, Subas Chandra, Rattan, Satish, Suklabaidya, Sujit   +3 more
core   +2 more sources

Simultaneous Determination of Sulfanilamide and Furosemide by Using Derivative Spectrophotometry

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
A simple, precise and accurate spectrophotometric method has been developed for simultaneous estimation of sulfanilamide and furosemide in their mixture by using first and second order derivative method in the ultraviolet region.
Samar A. Darweesh
doaj  

New Sulfanilamide Derivatives Incorporating Heterocyclic Carboxamide Moieties as Carbonic Anhydrase Inhibitors

Pharmaceuticals, 2021
Carbonic Anhydrases (CAs) are ubiquitous metalloenzymes involved in several disease conditions. There are 15 human CA (hCA) isoforms and their high homology represents a challenge for the discovery of potential drugs devoid of off-target side effects ...
Andrea Angeli, Victor Kartsev, Anthi Petrou, Mariana Pinteala, Roman M. Vydzhak, Svitlana Y. Panchishin, Volodymyr Brovarets, Viviana De Luca, Clemente Capasso, Athina Geronikaki, Claudiu T. Supuran   +10 more
doaj   +1 more source

Deciphering the Toxicity of Metal Tungstates and Molybdates: Effects on L929 Cell Metabolic Activity, Oxidative Stress, and Genotoxicity

Journal of Applied Toxicology, EarlyView.
ABSTRACT The increasing development and application of metal‐based materials in biomedical and environmental fields raise important concerns regarding their potential cytotoxic and genotoxic effects. Metal tungstates (MxWO4) and molybdates (MxMoO4) offer promising functional properties in health and environmental solutions but require safety validation
Marcelo Assis, Amanda de Souza, Karolyne dos Santos Jorge Sousa, Diana Gabriela Nina Nina, Mirian Bonfacio, Renata Neves Granito, Ana Claudia Muniz Rennó   +6 more
wiley   +1 more source