Using an OPEN UMS format for document flow formalization in medicine [PDF]
The question about construction of medical documents by means of AURRORA MIS with the use of the Open UMS format is considered in the work. The approach suggested allows data storage in the electronic form suitable for generation of required statistical ...
Korneva, I. O.+2 more
core +2 more sources
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jessica H. Whiteside+3 more
wiley +1 more source
Gas-phase acidity of sulfonamides: implications for reactivity and prodrug design [PDF]
A computational study at the density functional theory level was performed on bioactive and model sulfonamides with the aim of determining the factors affecting the acidity of the sulfonamido group.
Gomes, JRB, Gomes, P
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Amino acids as selective acylating agents: regioselective N-1-acylation of imidazolidin-4-one derivatives of the antimalarial drug primaquine [PDF]
The acylation of bioactive primaquine-based imidazolidin-4-ones was studied using N-chi-Boc-protected glycine as acylating agent. Two synthesis routes, eight different coupling methods and seven distinct solvents were compared.
Joana Matos+3 more
core +1 more source
Synthesis of new quinoline scaffolds via a solvent-free fusion method and their anti-microbial properties [PDF]
Purpose: To develop a robust and simple fusion-based methodology for the synthesis of various 5-(-3- nitrophenyl) pyrimido[5,4-c] quinoline-2,4(1H,3H)-diones (5 – 9).Method: The synthesis involved formation of a Knoevenagel product using barbituric acid ...
Mubeen, Sidra+2 more
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Synthesis and Characterization of Azo Dye Para Red and New Derivatives [PDF]
Azo dyes para red was synthesized. The products were characterized by FTIR and UV-Visible spectrophotometers.
L. Abd-Alredha R. Al-Rubaie+1 more
core +2 more sources
Photosynthesis of NH3 from NO3− Using CH4 in Homogenous Rhenium Catalysis
We present a Re catalysis of one‐pot synthesis of NH3 from NO3− using CH4 as a reductant under UV light irradiation. We are able to directly convert NO3−, leading to several environmental issues, to NH3, an essential compound as a fertilizer and industrial raw material, by means of CH4, which has a high affinity with renewable resource/energy, as a ...
Genta Nakamura+7 more
wiley +2 more sources
Study of Antibiotic Resistance of the Oropharyngeal Hemolytic Microflora in Preschool Children [PDF]
It is impossible to imagine modern medical practice without antibiotic therapy. However, the rapid development of the pharmaceutical industry expands free access of the population to antibacterial drugs.
Kolesnikova, S G+5 more
core +2 more sources
T cell receptor variable β20-1 harbors a nucleotide binding pocket in the CDR2β loop. [PDF]
Novel aspects of T cells containing TCRVβ20-1 are numerous, ranging from pathogen specific reactivity to specific tissue homing, or possible T cell subsets. Recently, it was demonstrated that TCR itself could become reactive by binding to small molecules
Pichler, Werner J, Watkins, Stephan
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Paradigm of modern pharmacology: development and current approaches [PDF]
The article focuses on the current approach to understanding pharmaceutical products’ effect. It describes a paradigm shift in views on pharmaceutical action in correlation to the processes occurring under pathology.
Reznikov, K. M.
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