In Vitro CO-Releasing and Antioxidant Properties of Sulfonamide-Based CAI-CORMs in a H<sub>2</sub>O<sub>2</sub>-Stimulated Human Achilles Tendon-Derived Cell Model. [PDF]
MoleculesTendinopathy is often described as a complex and multifactorial condition which affects tendons. Tendon disorders are marked by a reduction in mechanical function, accompanied by pain and swelling.
Berrino E +11 more
europepmc +3 more sources
Geophysical Monograph Series, Page 263-304., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jessica H. Whiteside +3 more
wiley +1 more source
Using an OPEN UMS format for document flow formalization in medicine [PDF]
, 2017 The question about construction of medical documents by means of AURRORA MIS with the use of the Open UMS format is considered in the work. The approach suggested allows data storage in the electronic form suitable for generation of required statistical ...
Korneva, I. O. +2 more
core +2 more sources
Amino acids as selective acylating agents: regioselective N-1-acylation of imidazolidin-4-one derivatives of the antimalarial drug primaquine [PDF]
, 2008 The acylation of bioactive primaquine-based imidazolidin-4-ones was studied using N-chi-Boc-protected glycine as acylating agent. Two synthesis routes, eight different coupling methods and seven distinct solvents were compared.
Joana Matos +3 more
core +1 more source
Gas-phase acidity of sulfonamides: implications for reactivity and prodrug design [PDF]
, 2005 A computational study at the density functional theory level was performed on bioactive and model sulfonamides with the aim of determining the factors affecting the acidity of the sulfonamido group.
Gomes, JRB, Gomes, P
core +1 more source
A Case of Multiple Antibiotic-Associated Hepatotoxicity in an Infant
Безопасность и риск фармакотерапии, 2019 Drug induced liver injury is one of the most frequent reasons for stopping treatment and the main cause of the onset and progression of acute liver failure, requiring liver transplantation.
S. S. Postnikov +7 more
doaj +1 more source
Synthesis and Characterization of Azo Dye Para Red and New Derivatives [PDF]
, 2012 Azo dyes para red was synthesized. The products were characterized by FTIR and UV-Visible spectrophotometers.
L. Abd-Alredha R. Al-Rubaie +1 more
core +5 more sources
Paradigm of modern pharmacology: development and current approaches [PDF]
, 2016 The article focuses on the current approach to understanding pharmaceutical products’ effect. It describes a paradigm shift in views on pharmaceutical action in correlation to the processes occurring under pathology.
Reznikov, K. M.
core +2 more sources
Applied Computational Techniques on Schizophrenia Using Genetic Mutations [PDF]
, 2013 [Abstract] Schizophrenia is a complex disease, with both genetic and environmental influence. Machine learning techniques can be used to associate different genetic variations at different genes with a (schizophrenic or non-schizophrenic) phenotype ...
Aguiar-Pulido, Vanessa +4 more
core +2 more sources
Mapping the scarcity of data on antibiotics in natural and engineered water environments across India. [PDF]
Front AntibiotAntimicrobial resistance is a growing public health concern, increasingly recognized as a silent pandemic across the globe. Therefore, it is important to monitor all factors that could contribute to the emergence, maintenance and spread of antimicrobial ...
Rathinavelu S +5 more
europepmc +3 more sources