Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate. [PDF]
associated with aging. Thus, the question arises whether or not a correlation exists between the well known prostatic androgen and estrogen accumulation and aging.
Krieg, Michael, Nass, Ralf, Tunn, Sabine
core +1 more source
Dental Abnormalities in Congenital Ichthyoses: Case Report and Review of the Literature
ABSTRACT We describe a 1‐day old female with features of keratitis‐ichthyosis‐deafness (KID) syndrome and natal teeth. Genetic analysis confirmed GJB2 263C and A88V de novo pathogenic variants consistent with KID syndrome. Natal teeth were promptly extracted to avoid the risk of aspiration.
Sarah Maarouf+3 more
wiley +1 more source
Multiple sulfatase deficiency: A case series of four children
Multiple sulfatase deficiency is biochemically characterized by the accumulation of sulfated lipids and acid mucopolysaccharides. The gene sulfatase-modifying factor 1 (SUMF1), recently identified, encodes the enzyme responsible for post-translational ...
Faruk Incecik+7 more
doaj +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon+6 more
wiley +1 more source
A single sulfatase is required to access colonic mucin by a gut bacterium
A. Luis+20 more
semanticscholar +1 more source
Proteolytic cleavage of the rat heparan sulfate 6-O-endosulfatase SulfFP2 by furintype proprotein convertases [PDF]
journal ...
KEINO-MASU Kazuko+3 more
core +1 more source
Novel CTSA Variant Identified in a Thai Family With Late‐Infantile Galactosialidosis
ABSTRACT Galactosialidosis (GS) is a rare lysosomal storage disease (LSD) with variable onset caused by a defect in protective protein/cathepsin A (PPCA) encoded by the CTSA gene. The late‐infantile onset is characterized by developmental delay, visceromegaly, coarse facies, and cherry‐red macula.
Lukana Ngiwsara+6 more
wiley +1 more source
Identification and characterization of a glycosulfatase-encoding gene cluster in Bifidobacterium breve UCC2003 [PDF]
Bifidobacteria constitute a specific group of commensal bacteria, typically found in the gastrointestinal tract (GIT) of humans and other mammals. Bifidobacterium breve strains are numerically prevalent among the gut microbiota of many healthy breast-fed
Egan, Muireann+4 more
core +1 more source
Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts [PDF]
BACKGROUND: Extracellular human sulfatases modulate growth factor signaling by alteration of the heparin/heparan sulfate proteoglycan (HSPG) 6-O-sulfation state.
Alicia Gómez-Yafal+11 more
core +2 more sources
Biodegradation of anionic surfactants, like sodium dodecyl sulfate (SDS) are challenged by some bacteria through the function of the enzyme alkyl sulfatases.
B. Icgen+4 more
semanticscholar +1 more source