Results 101 to 110 of about 22,801 (226)

SARS-CoV Regulates Immune Function-Related Gene Expressions in Human Monocytic Cells [PDF]

open access: yes, 2011
Background: Severe Acute Respiratory Syndrome (SARS) is characterized by acute respiratory distress (ARDS) and pulmonary fibrosis, and the monocyte/macrophage is the key player in the pathogenesis of SARS. Methods: In this study, we ...
Betty A. Wu-Hsieh   +4 more
core   +1 more source

Parathyroid localization [PDF]

open access: yes, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B.   +7 more
core   +1 more source

Researches on Sulfatase Models, IV

open access: yesNIPPON KAGAKU KAISHI, 1939
unsym.メチルフェニルヒドラヂンはヒドラヂン以上にグルコーゼ硫酸の分解を促進するが, Sym.アセチルフェニルヒドラヂンは全くその作用がない.從つてグルコスルフ,ターゼ模型としての作用を有する爲にはヒドラヂンの少くとも1個のアミノ基は遊離して居なければならないと思はれる.グルコスルファターゼ模型としてのヒドラヂンの特異性は必ずしもグルコスルファターゼの特異性と現在見做されて居るもの2)とは一致しない.即ち,バウシウボラより得られたグルコスルファターゼ製品はα-メチルグルコシド硫酸,蔗糖硫酸等をも分解するが,ヒドラヂンは,ヒドラヂン誘導體縮合生成物を作る様な還元糖等の硫酸エステルに限り分解する.
openaire   +6 more sources

Genetic and Metabolic Controls for Sulfate Metabolism in \u3cem\u3eNeurospora crassa\u3c/em\u3e: Isolation and Study of Chromate-Resistant and Sulfate Transport-Negative Mutants [PDF]

open access: yes, 1970
Mutants of Neurospora resistant to chromate were selected and all were found to map at a single genetic locus designated as cys-13. The chromate-resistant mutants grow at a wild-type rate on minimal media but are partially deficient in the transport of ...
Marzluf, George A.
core   +1 more source

Quantification of the enzyme activities of iduronate-2-sulfatase, N-acetylgalactosamine-6-sulfatase and N-acetylgalactosamine-4-sulfatase using liquid chromatography-tandem mass spectrometry

open access: yesMolecular Genetics and Metabolism Reports, 2018
Mucopolysaccharidosis (MPS) is a genetic disorder characterized by the accumulation of glycosaminoglycans in the body. Of the multiple MPS disease subtypes, several are caused by defects in sulfatases.
Ryuichi Mashima   +3 more
doaj   +1 more source

Recognition and ER Quality Control of Misfolded Formylglycine-Generating Enzyme by Protein Disulfide Isomerase

open access: yesCell Reports, 2018
Summary: Multiple sulfatase deficiency (MSD) is a fatal, inherited lysosomal storage disorder characterized by reduced activities of all sulfatases in patients.
Lars Schlotawa   +6 more
doaj   +1 more source

Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
Ring A halogenated 13α-, 13β-, and 17-deoxy-13α-estrone derivatives were synthesised with N-halosuccinimides as electrophile triggers. Substitutions occurred at positions C-2 and/or C-4.
Ildikó Bacsa   +10 more
doaj   +1 more source

Riding the sulfur cycle - metabolism of sulfonates and sulfate esters in Gram-negative bacteria [PDF]

open access: yes, 2017
Sulfonates and sulfate esters are widespread in nature, and make up over 95% of the sulfur content of most aerobic soils. Many microorganisms can use sulfonates and sulfate esters as a source of sulfur for growth, even when they are unable to metabolize ...
Kertesz, Michael A.
core  

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]

open access: yes, 2019
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core   +1 more source

Neonatal multiple sulfatase deficiency with a novel mutation and review of the literature

open access: yesThe Turkish Journal of Pediatrics, 2014
Multiple sulfatase deficiency is a rare autosomal recessive disorder in which affected individuals present a complex phenotype due to the impaired activity of all sulfatases.
Banu Güzel Nur   +7 more
doaj  

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