Results 101 to 110 of about 15,873 (215)

Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Ring A halogenated 13α-, 13β-, and 17-deoxy-13α-estrone derivatives were synthesised with N-halosuccinimides as electrophile triggers. Substitutions occurred at positions C-2 and/or C-4.
Ildikó Bacsa, Bianka Edina Herman, Rebeka Jójárt, Kevin Stefán Herman, János Wölfling, Gyula Schneider, Mónika Varga, Csaba Tömböly, Tea Lanišnik Rižner, Mihály Szécsi, Erzsébet Mernyák   +10 more
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Neonatal multiple sulfatase deficiency with a novel mutation and review of the literature

The Turkish Journal of Pediatrics, 2014
Multiple sulfatase deficiency is a rare autosomal recessive disorder in which affected individuals present a complex phenotype due to the impaired activity of all sulfatases.
Banu Güzel Nur, Ercan Mıhçı, Stefano Pepe, Gürsel Biberoğlu, Fatih Süheyl Ezgü, Andrea Ballabio, Osman Öztekin, Oğuz Dursun   +7 more
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Scavestrogen sulfamates: correlation between estrone sulfatase inhibiting and antioxidant effects

, 1998
In the present study estrone sulfatase (steryl-sulfatase; EC 3.1.6.2) and phenylsulfatase (arylsulfatase B; EC 3.1.6.1) inhibiting as well as antioxidant effects exerted by ring B,C unsaturated sulfamates of estrone (J 1025), 17 beta -estradiol (J 1054,
Wolfgang Römer, Sigfrid Schwarz, Michael Oettel   +2 more
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Studies on Cerebroside Sulfate Sulfatase in Multiple Sulfatase Deficiency Cultured Skin Fibroblasts [PDF]

The measurement of cerebroside sulfate （CS） sulfatase both in vitro and in vivo after uptake of 14C-CS were performed at different conditions in Metachromatic leukodystrophy （MLD） and Multiple sulfatase deficiency （MSD） cultured skin fibroblasts.
星井, 桜子
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Active Site Directed Inhibition of Estrone Sulfatase by Nonsteroidal Coumarin Sulfamates

, 2016
Active Site Directed Inhibition of Estrone Sulfatase by Nonsteroidal Coumarin ...
L. W. Lawrence Woo (2225101), Michael J. Reed (494088), Atul Purohit (1064), Barry V. L. Potter (286876)   +3 more
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Anaerobic sulfatase-maturating enzymes: radical SAM enzymes able to catalyze in vitro sulfatase post-translational modification.

, 2007
International audienceSulfatases are widespread enzymes, found from prokaryotes to eukaryotes and involved in many biochemical processes. To be active, all known sulfatases undergo a unique post-translational modification leading to the conversion of a ...
Benjdia, Alhosna, Guillot, Alain, Vaudry, Hubert, Berteau, Olivier, Leprince, Jérôme, Rabot, Sylvie   +5 more
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Bone marrow transplantation increases sulfatase activity in somatic tissues in a multiple sulfatase deficiency mouse model

Communications Medicine
Background Multiple Sulfatase Deficiency (MSD) is an ultra-rare autosomal recessive disorder characterized by deficient enzymatic activity of all known sulfatases. MSD patients frequently carry two loss of function mutations in the SUMF1 gene, encoding a
Maximiliano Presa, Vi Pham, Somdatta Ray, Pierre-Alexandre Piec, Jennifer Ryan, Timothy Billings, Harold Coombs, Lars Schlotawa, Troy Lund, Rebecca C. Ahrens-Nicklas, Cathleen Lutz   +10 more
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Anaerobic Sulfatase-Maturating Enzymes:  Radical SAM Enzymes Able To Catalyze in Vitro Sulfatase Post-translational Modification

, 2016
Sulfatases are widespread enzymes, found from prokaryotes to eukaryotes and involved in many biochemical processes. To be active, all known sulfatases undergo a unique post-translational modification leading to the conversion of a critical active-site ...
Sylvie Rabot (79706), Alhosna Benjdia (1962052), Jérôme Leprince (167385), Alain Guillot (176760), Olivier Berteau (1357398), Hubert Vaudry (222744)   +5 more
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Catch Bond Interaction Between Glycosaminoglycans and Cell Surface Sulfatase Sulf1

, 2014
Harder A, Moeller A-K, Milz F, et al. Catch Bond Interaction Between Glycosaminoglycans and Cell Surface Sulfatase Sulf1. Biophysical Journal.
Phillipp Neuhaus, Thomas Dierks, Milz, Fabian, Walhorn, Volker ; https://orcid.org/, Neuhaus, Phillipp, Harder, Alexander, Moeller, Ann-Kristin, Dario Anselmetti, Ann-Kristin Moeller, Volker Walhorn, Alexander Harder, Dierks, Thomas, Fabian Milz, Anselmetti, Dario ; https://orcid.org/   +13 more
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Isolation of a strain of Pseudomonas putida capable of metabolizing anionic detergent sodium dodecyl sulfate (SDS)

Iranian Journal of Microbiology, 2011
Background and objectives: Sodium Dodecyl Sulfate (SDS) is one of the most widely used anionic detergents. The present study deals with isolation and identification of SDS-degrading bacteria from a detergent contaminated pond situated in Varanasi city ...
V Chaturvedi, A Kumar
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