Results 91 to 100 of about 15,873 (215)

Small Proteoglycans, Big Impact: Decorin, Biglycan, and Asporin in Musculoskeletal Tissue Health and Disease

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT The extracellular matrix (ECM) is a dynamic and information‐rich network that integrates structural support with biochemical and mechanical signaling. Among its key regulatory components are the Small Leucine‐Rich Proteoglycans (SLRPs), a family of matrix molecules that coordinate extracellular architecture with cell signaling.
Alessandra Leone, Zsuzsa Jenei‐Lanzl, Frank Zaucke   +2 more
wiley   +1 more source

Evaluation of sulfatase-directed quinone methide traps for proteomics

, 2012
Lenger J, Schröder M, Ennemann E, et al. Evaluation of sulfatase-directed quinone methide traps for proteomics. Bioorganic & Medicinal Chemistry. 2012;20(2):622-627.Sulfatases hydrolytically cleave sulfate esters through a unique catalytic aldehyde ...
Thomas Dierks, Marius Schröder, Wong, C.-H., Benjamin Müller, Norbert Sewald, Müller, Benjamin, Noll, Thomas ; https://orcid.org/, Sewald, Norbert ; https://orcid.org/, Schröder, Marius, Eva C. Ennemann, Sarah R. Hanson, Thomas Noll, Dierks, Thomas, Chi-Huey Wong, Lenger, Janina, Hanson, Sarah R., Janina Lenger, Ennemann, Eva   +17 more
core   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, Volume 49, Issue 10, Page 7558-7574, October 2026.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

Diagnosis and treatment of multiple sulfatase deficiency and other sulfatase deficiencies

, 2004
von Figura K, Schmidt B, Dierks T, Heartlein M, Ballabio A, Cosma MP.
Ballabio, Andrea, von Figura, Kurt, Cosma, Maria Pia, Dierks, Thomas, Heartlein, Michael, Schmidt, Bernhard   +5 more
core  

Sulfatase mediated manipulation of the astrocyte-Schwann cell interface [PDF]

, 2017
Schwann cell (SC) transplantation following spinal cord injury (SCI) may have therapeutic potential. Functional recovery is limited however, due to poor SC interactions with host astrocytes and the induction of astrogliosis.
O'Neill, Paul, Fagoe, N, John S. Riddell, Fagoe, Nitish, Andreea Pantiru, Riddell, John S., Jeremy E. Turnbull, Lindsay, Susan L., Pantiru, Andreea, Riddell, JS, Verhaagen, J, Paul O'Neill, Lindsay, SL, Guimond, Scott E., Susan C. Barnett, Nitish Fagoe, Scott E. Guimond, Verhaagen, Joost, Turnbull, Jeremy E., Pantiru, A, Joost Verhaagen, Barnett, SC, Turnbull, JE, Guimond, SE, Barnett, Susan C., O'Neill, P, Susan L. Lindsay, Turnbull, Jeremy, Guimond   +28 more
core   +1 more source

Regulation of Steroid Sulfatase in Human Breast Cancer Cells and Screening of Human Tissues for Steroid Sulfatase Status [PDF]

, 2003
Breast cancer is the most frequently occurring cancer in women and is the second leading cause of death. About 40% of breast cancers are hormone-dependent and require estrogen for their growth.
Chandra, Abhinav
core  

Activity-based fluorescent probes for monitoring sulfatase activity

, 2014
A small-molecule probe for sulfatase is developed that shows a significant change in fluorescence upon reaction with sulfatase in an activity-based manner. As this probe is free from interference from background fluorescence caused by an unreacted probe,
Park, Hyun-Joo, Rhee, Hyun-Woo, Hong, Jong-In   +2 more
core   +1 more source

Quantification of the enzyme activities of iduronate-2-sulfatase, N-acetylgalactosamine-6-sulfatase and N-acetylgalactosamine-4-sulfatase using liquid chromatography-tandem mass spectrometry

Molecular Genetics and Metabolism Reports, 2018
Mucopolysaccharidosis (MPS) is a genetic disorder characterized by the accumulation of glycosaminoglycans in the body. Of the multiple MPS disease subtypes, several are caused by defects in sulfatases.
Ryuichi Mashima, Mari Ohira, Torayuki Okuyama, Akiya Tatsumi   +3 more
doaj   +1 more source

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency

Cell, 1995
Multiple sulfatase deficiency (MSD) is a lysosomal storage disorder characterized by a decreased activity of all known sulfatases. The deficiency of sulfatases was proposed to result from the lack of a co- or posttranslational modification that is common to all sulfatases and required for their catalytic activity.
Schmidt, Bernhard, Selmer, Thorsten, Ingendoh, Arnd, Figura, Kurt von   +3 more
openaire   +4 more sources

Multiple Sulfatase Deficiency

, 2009
von Figura K, Dierks T, Schmidt B. Multiple Sulfatase Deficiency. In: Lang F, ed. Encyclopedia of Molecular Mechanisms of Disease.
Lang, F., von Figura, Kurt, Dierks, Thomas, Schmidt, Bernhard   +3 more
core