Results 11 to 20 of about 14,179 (284)

Identification and Action Patterns of Two Chondroitin Sulfate Sulfatases From a Marine Bacterium Photobacterium sp. QA16

open access: yesFrontiers in Microbiology, 2022
Chondroitin sulfate (CS)/dermatan sulfate (DS) is a kind of sulfated polyanionic, linear polysaccharide belonging to glycosaminoglycan. CS/DS sulfatases, which specifically hydrolyze sulfate groups from CS/DS oligo-/polysaccharides, are potential tools ...
Lin Wei   +10 more
doaj   +2 more sources

Matching the Diversity of Sulfated Biomolecules: Creation of a Classification Database for Sulfatases Reflecting Their Substrate Specificity. [PDF]

open access: yesPLoS ONE, 2016
Sulfatases cleave sulfate groups from various molecules and constitute a biologically and industrially important group of enzymes. However, the number of sulfatases whose substrate has been characterized is limited in comparison to the huge diversity of ...
Tristan Barbeyron   +7 more
doaj   +2 more sources

Fucoidan Sulfatases from Marine Bacterium Wenyingzhuangia fucanilytica CZ1127T

open access: yesBiomolecules, 2018
Fucoidans belong to a structurally heterogeneous class of sulfated polysaccharides isolated from brown algae. They have a wide spectrum of biological activities.
Artem S. Silchenko   +7 more
doaj   +2 more sources

Identification and Signature Sequences of Bacterial Δ4,5Hexuronate-2-O-Sulfatases

open access: yesFrontiers in Microbiology, 2019
Glycosaminoglycan (GAG) sulfatases, which catalyze the hydrolysis of sulfate esters from GAGs, belong to a large and conserved sulfatase family. Bacterial GAG sulfatases are essential in the process of sulfur cycling and are useful for the structural ...
Shumin Wang   +4 more
doaj   +2 more sources

Phylogeny of algal sequences encoding carbohydrate sulfotransferases, formylglycine-dependent sulfatases and putative sulfatase modifying factors

open access: yesFrontiers in Plant Science, 2015
Many algae are rich sources of sulfated polysaccharides with biological activities. The physicochemical/rheological properties and biological activities of sulfated polysaccharides are affected by the pattern and number of sulfate moieties.
Chai-Ling eHo
doaj   +2 more sources

Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells. [PDF]

open access: yesPLoS ONE, 2007
Heparan sulfate proteoglycans (HSPGs) are control elements in Wnt signaling, which bind extracellularly to Wnt ligands and regulate their ability to interact with signal transduction receptors on the cell surface.
Roman Nawroth   +5 more
doaj   +2 more sources

Comparative Study of Two Chondroitin Sulfate/Dermatan Sulfate 4-O-Sulfatases With High Identity

open access: yesFrontiers in Microbiology, 2019
Chondroitin sulfate/dermatan sulfate (CS/DS) sulfatases are potential tools for structural and functional studies of CD/DS chains. In our previous study, a CS/DS 4-O-endosulfatase (endoVB4SF) was identified from a marine bacterium (Wang et al., 2015 ...
Shumin Wang   +6 more
doaj   +2 more sources

The role of heparanase and sulfatases in the modification of heparan sulfate proteoglycans within the tumour microenvironment and opportunities for novel cancer therapeutics

open access: yesFrontiers in Oncology, 2014
Heparan sulfate proteoglycans (HSPGs) are an integral and dynamic part of normal tissue architecture at the cell surface and within the extracellular matrix (ECM).
Edward eHammond   +3 more
doaj   +2 more sources

Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship [PDF]

open access: yesHuman Molecular Genetics, 2005
Sulfatases catalyze the hydrolysis of sulfate ester bonds from a wide variety of substrates. Several human inherited diseases are caused by the deficiency of individual sulfatases, while in patients with multiple sulfatase deficiency mutations in the Sulfatase Modifying Factor 1 (SUMF1) gene cause a defect in the post-translational modification of a ...
SARDIELLO M.   +3 more
openaire   +4 more sources

Genomic and Functional Characterization of Environmental Strains of SDS-Degrading Pseudomonas spp., Providing a Source of New Sulfatases

open access: yesFrontiers in Microbiology, 2018
Biochemical, physiological and genomic comparisons of two Pseudomonas strains, assigned previously to the Pseudomonas jessenii subgroup, which are efficient SDS-degraders were carried out. A GO enrichment analysis showed that the genomes of SDS-degraders
Ewa M. Furmanczyk   +5 more
doaj   +2 more sources

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