Results 41 to 50 of about 1,440,713 (245)

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Removal of methylene blue from synthetic industrial wastewater by using geopolymer prepared from partially dealuminated metakaolin

Scientific Reports
Industrial wastewater frequently contains a huge of pollutants, such as heavy metals, dyes, and organic compounds, leading to considerable environmental discharge. Methylene Blue (MB), a cationic dye extensively utilized in the textile and pharmaceutical
Khaled Elewa, A. F. Tawfic, Mostafa Tarek, Nabil Abdullah Al-Sagheer, Nabil M. Nagy   +4 more
doaj   +1 more source

Crystal Structures of Two 1,4-Diamino-1,2,4-triazolium Salts

Crystals, 2016
Bis(1,4-diamino-1,2,4-triazolium) sulfate (1) was obtained from the corresponding chloride by ion metathesis using Ag2SO4. Further metathesis with barium 5,5′-azotetrazolate yielded bis(1,4-diamino-1,2,4-triazolium) 5,5′-azotetrazolate (2). Numerous NH···
Gerhard Laus, Klaus Wurst, Volker Kahlenberg, Herwig Schottenberger   +3 more
doaj   +1 more source

Bis(2-aminobenzimidazolium) sulfate monohydrate

IUCrData, 2022
In the title hydrated molecular salt, 2C7H8N3+·SO42−·H2O, the components are linked by numerous N—H...O and O—H...O hydrogen bonds.
Adrian Peña Hueso, Adriana Esparza Ruiz, Angelina Flores Parra   +2 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Effect of Addition Catalyst Sulfate Acid and Solvents (Ch3oh) Biodiesel Production Process of Seeds Nyamplung (Calophyllum Inophyllum) [PDF]

, 2012
Biodiesel is made by taking the oil from the seeds by pressing nyamplung then processed through two stages of esterification and transesterification of the oil with solvent ratio between 1:1, 1:2, 1:3, 1:4 and 1:6 and added catalyst H2SO4 at process of ...
S.T., M.T., Hilwatullisan
core  

Charge Characteristics of Agouti-Related Protein Implicate Potent Involvement of Heparan Sulfate Proteoglycans in Metabolic Function. [PDF]

, 2019
The endogenous melanocortin peptide agouti-related protein (AgRP) plays a well-known role in foraging, but its contribution to metabolic regulation is less understood.
Chen, Jihuan, Chen, Valerie, Hoang, Ivy, Kawamura, Tomoya, McBride, Ryan, Millhauser, Glenn L, Repunte-Canonigo, Vez, Sanna, Pietro Paolo, Wong, Ashley Tess, Yang, Yang   +9 more
core   +1 more source

Fontes e doses de potássio na produção e qualidade do grão de café beneficiado Sources and doses of potassium on the yield and quality of green coffee

Pesquisa Agropecuária Brasileira, 1999
Um experimento de campo foi instalado num Latossolo Roxo distrófico, localizado na Fazenda Experimental da EPAMIG, São Sebastião do Paraíso, MG, em fevereiro de 1993, utilizando-se a espécie Coffea arabica L., cultivar Catuaí Vermelho, linhagem LCH 2077 ...
Enilson de Barros Silva, Francisco Dias Nogueira, Paulo Tácito Gontijo Guimarães, Silvio Júlio de Rezende Chagas, Laerte Costa   +4 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Genetic and Metabolic Controls for Sulfate Metabolism in \u3cem\u3eNeurospora crassa\u3c/em\u3e: Isolation and Study of Chromate-Resistant and Sulfate Transport-Negative Mutants [PDF]

, 1970
Mutants of Neurospora resistant to chromate were selected and all were found to map at a single genetic locus designated as cys-13. The chromate-resistant mutants grow at a wild-type rate on minimal media but are partially deficient in the transport of ...
Marzluf, George A.
core   +1 more source