Results 41 to 50 of about 1,584,676 (342)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Determination of lipid-bound sulfate by ion chromatography and its application to quantification of sulfolipids from kidneys of various mammalian species

Journal of Lipid Research, 2001
A variety of procedures have been developed for determining the sulfate ester content of various biomolecules. Ion chromatography (IC), that is, quantitation of ionic substances by ion conductimetry after separation by anion-exchange chromatography, has ...
Keiko Tadano-Aritomi, Toshiyuki Hikita, Atsushi Suzuki, Hidenao Toyoda, Toshihiko Toida, Toshio Imanari, Ineo Ishizuka   +6 more
doaj   +1 more source

Origins of Sulfate in Groundwater and Surface Water of the Rio Grande Floodplain, Texas, USA and Chihuahua, Mexico

Hydrology, 2022
Sulfate isotopes (δ34S, δ18OSO4) interpreted in conjunction with sulfate concentrations show that sulfate of both agricultural and geologic sources is present in groundwater and surface water in the Rio Grande flood plain within the Hueco Bolsón.
Christopher Eastoe, Barry Hibbs, Mercedes Merino, Jason Dadakis   +3 more
doaj   +1 more source

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. [PDF]

, 2019
Hepcidin is a liver-derived peptide hormone that controls systemic iron homeostasis. Its expression is regulated by the bone morphogenetic protein 6 (BMP6)/SMAD1/5/8 pathway and by the proinflammatory cytokine interleukin 6 (IL6).
Anower-E-Khuda, Ferdous, Arosio, Paolo, Asperti, Michela, Denardo, Andrea, Esko, Jeffrey D, Gordts, Philip LSM, Gryzik, Magdalena, Poli, Maura, Ruzzenenti, Paola   +8 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Utilizing metakaolin and siliceous waste from the alum industry to create geopolymer adsorbent for the removal of certain heavy metals

Scientific Reports
A geopolymer (GP) from Partially Dealuminated Kaolin (PDK) was synthesized. PDK is a solid waste of alum industry, it was produced in a big quantity, which need careful management to be recycled for protection of the environment against pollution ...
Khaled Elewa, A. F. Tawfic, Mostafa Tarek, Nabil Abdullah Al-Sagheer, Nabil M. Nagy   +4 more
doaj   +1 more source

Genetic and Metabolic Controls for Sulfate Metabolism in \u3cem\u3eNeurospora crassa\u3c/em\u3e: Isolation and Study of Chromate-Resistant and Sulfate Transport-Negative Mutants [PDF]

, 1970
Mutants of Neurospora resistant to chromate were selected and all were found to map at a single genetic locus designated as cys-13. The chromate-resistant mutants grow at a wild-type rate on minimal media but are partially deficient in the transport of ...
Marzluf, George A.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Removal of methylene blue from synthetic industrial wastewater by using geopolymer prepared from partially dealuminated metakaolin

Scientific Reports
Industrial wastewater frequently contains a huge of pollutants, such as heavy metals, dyes, and organic compounds, leading to considerable environmental discharge. Methylene Blue (MB), a cationic dye extensively utilized in the textile and pharmaceutical
Khaled Elewa, A. F. Tawfic, Mostafa Tarek, Nabil Abdullah Al-Sagheer, Nabil M. Nagy   +4 more
doaj   +1 more source

Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli

Biology, 2013
Fimbriae are long, proteinaceous adhesion organelles expressed on the bacterial envelope, evolutionarily adapted by Escherichia coli strains for the colonization of epithelial linings. Using glycan arrays of the Consortium for Functional Glycomics (CFG),
Manfred Wuhrer, Julie Bouckaert, Stefan Oscarson, André M. Deelder, Yann Guérardel, Emeline Fabre, Johan D. M. Olsson, Manfred S. Weiss, Lieven Buts, Arjen R. de Boer, Emanuela Lonardi, Kristof Moonens   +11 more
doaj   +1 more source