Results 141 to 150 of about 19,259 (181)

Immunostimulating Effects of a Sulfated Galactan From Codium Fragile

Carbohydrate Research, 2010
A pyruvylated sulfated galactan from Codium fragile is a highly ramified polysaccharide consisting of 3-linked, 3,6-linked, and non-reducing terminal d-galactose with pyruvate and sulfate groups; the glycan exerts anti-herpes simplex virus type 2 effects in vitro and in vivo.
Jung-Bum Lee
exaly   +3 more sources

Immunomodulatory and anti-inflammatory and anticancer activities of porphyran, a sulfated galactan

Carbohydrate Polymers, 2023
Seaweeds are high in bioactive chemicals frequently used to treat human illnesses. Porphyran is a polysaccharide found in the red seaweeds of the genus Porphyra. Porphyran has been discovered to have immunomodulatory, anti-inflammatory activity, and anti-cancer effects via boosting immunity and targeting important apoptotic molecules, making them ...
Biswajita, Pradhan, Laxmidhar, Rout, Jang-Seu, Ki   +2 more
openaire   +2 more sources

Isolation of Sulfated Galactan From Codium Fragile and Its Antiviral Effect.

Biological and Pharmaceutical Bulletin, 2009
A sulfated galactan (FG) was isolated from the green alga, Codium fragile. Chemical analysis revealed that FG mainly consisted of D-galactose with pyruvic acid (12.3%) and sulfate (11.0%). Methylation and NMR analyses showed that FG was composed of -->3)-beta-D-Galp-(1-->, beta-D-Galp-(1--> and -->3,6)-beta-D-Galp-(1--> residue.
Jung-Bum Lee
exaly   +4 more sources

Conformation of sulfated galactan and sulfated fucan in aqueous solutions: Implications to their anticoagulant activities

Journal of Molecular Graphics and Modelling, 2007
The discovery of sulfated galactans and sulfated fucans in marine invertebrates with simple and ordered structures opened new perspectives to investigate the biological activity of these molecules and to determine whether different structures confer high affinity for a particular protein. We undertook a conformational analysis of a 2-sulfated, 3-linked
Camila F, Becker, Jorge A, Guimarães, Paulo A S, Mourão, Hugo, Verli   +3 more
openaire   +2 more sources

The structure of a galactan sulfate from the red seaweed Bostrychia montagnei

Carbohydrate Research, 2002
The sulfated, methylated galactan isolated from the red seaweed Bostrychia montagnei, showed an unusually narrow structural dispersion. This agaran has the defining linear backbone of alternating 3-linked beta-D-galactopyranosyl units and 4-linked alpha-L-galactopyranosyl and 3,6-anhydrogalactopyranosyl residues.
Maria E R, Duarte, Miguel D, Noseda, Marco A, Cardoso, Siumara, Tulio, Alberto S, Cerezo   +4 more
openaire   +2 more sources

The Structure of a Sulfated Galactan From Porphyra haitanensis and Its in Vivo Antioxidant Activity

Carbohydrate Research, 2004
The sulfated galactan fraction F1 isolated from the red seaweed, Porphyra haitanensis, showed typical porphyran structure. It has a linear backbone of alternating 3-linked beta-D-galactosyl units and 4-linked alpha-L-galactosyl 6-sulfate and 3,6-anhydro-alpha-L-galactosyl units.
Quanbin Zhang, Zhien Li
exaly   +3 more sources

Sulfated galactan is a catalyst of antithrombin-mediated inactivation of α-thrombin

Biochimica et Biophysica Acta (BBA) - General Subjects, 2008
Novel compounds presenting anticoagulant activity, such as sulfated polysaccharides, open new perspectives in medicine. Elucidation of the molecular mechanism behind this activity is desirable by itself, as well as because it allows for the design of novel compounds.
Fábio R, Melo, Mariana S, Pereira, Robson Q, Monteiro, Débora, Foguel, Paulo A S, Mourão   +4 more
openaire   +2 more sources

A precipitation reaction between certain human G immunoglobulins and sulfated galactans

Immunochemistry, 1971
Abstract During electrophoresis, some pathological sera are seen to precipitate spontaneously in an agar gel and not in an agarose gel. Such sera come from G myelomas or malignant lymphomatosis cases. A similar precipitation is observed when either agaropectin or other sulfated galactans (but not other sulfated polysaccharides) are added to the same ...
P, Burtin, M C, Gendron
openaire   +3 more sources

A new sulfated β-galactan from clams with anti-HIV activity

Carbohydrate Research, 1999
A new polysaccharide composed of galactan sulfate with a beta-(1-->3)-glycosidic linkage has been isolated from the marine clam species Meretrix petechialis. The polysaccharide was homogeneous in its composition containing D-galactose. The glycosidic linkage was examined by 2D DQF-COSY and 2D NOESY spectroscopy. The coupling constant of anomeric proton
C, Amornrut, T, Toida, T, Imanari, E R, Woo, H, Park, R, Linhardt, S J, Wu, Y S, Kim   +7 more
openaire   +2 more sources

Structural and functional insights into sulfated galactans: a systematic review

Glycoconjugate Journal, 2009
Sulfated galactans (SGs) are highly anionic marine galactose-composed homopolysaccharides. Although their structures vary among species, their main features are conserved among phyla. Green algal SGs are quite heterogeneous, although preponderantly composed of 3-beta-D-Galp units.
openaire   +2 more sources