Sulfated fucans and a sulfated galactan from sea urchins as potent inhibitors of selectin-dependent hematogenous metastasis [PDF]
Glycobiology, 2018 Metastasis is responsible for the majority of cancer-associated deaths, though only a very small number of tumor cells are able to efficiently complete all the steps of that process. Tumor cell survival in the bloodstream is one of the limiting aspects of the metastatic cascade.
Felipe C O B Teixeira +5 more
core +6 more sources
Marine Drugs, 2018 The anticoagulant and antithrombotic properties of three structurally correlated sea urchin-derived 3-linked sulfated α-glycans and their low molecular-weight derivatives were screened comparatively through various in vitro and in vivo methods ...
Ariana A. Vasconcelos +6 more
doaj +2 more sources
Structural and Functional Properties of a Sulfated Polysaccharide Extracted from Mexican Red Algae
AnalyticaSulfated polysaccharides from red algae are multifunctional hydrocolloids whose properties depend strongly on molecular structure, sulfate content, and chain conformation.
David Encinas-Basurto +5 more
doaj +2 more sources
Sulfated Polysaccharides in the Freshwater Green Macroalga Cladophora surera Not Linked to Salinity Adaptation [PDF]
Frontiers in Plant Science, 2017 The presence of sulfated polysaccharides in cell walls of seaweeds is considered to be a consequence of the physiological adaptation to the high salinity of the marine environment.
Paula X. Arata +6 more
doaj +2 more sources
Preparation of a sulfated linear (1→4)-β-d-galactan with variable degrees of sulfation
Carbohydrate Polymers, 2000 A linear 1,4-β-d-galactan has been prepared by partial acid hydrolysis of the major lupin seed polysaccharide on a preparative scale. The galactan has been characterized by acetylation and methylation analysis, by GPC, as well as by its 1H- and 13C-NMR-spectra. Sulfation with increasing amounts of SO3-pyridine yielded a series of galactan sulfates with
H Vogl, D.H Paper, G Franz
openaire +2 more sources
Sulfated galactan from Acanthophora muscoides inhibits adipogenesis via regulating adipogenic transcription factors and AMPK in 3T3-L1 cells [PDF]
Brazilian Journal of BiologyObesity is a global public health issue, closely linked to cardiovascular disease and type 2 diabetes. Pharmacological interventions for weight loss are one option for treating obesity; however, these drugs often come with side effects or limited ...
A. V. L. Silva +5 more
doaj +3 more sources
Frontiers in Bioscience-LandmarkBackground: The biological activities of sulfated polysaccharides (SP) are well-documented, especially regarding wound healing. Sulfated galactan (SG), a type of SP extracted from the red seaweed Gracilaria fisheri, has been identified
Kamonwan Jongsomchai +5 more
doaj +2 more sources
Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties. [PDF]
J Biol Chem, 2022 Sulfation pattern and molecular weight (MW) play a key role in the biological actions of sulfated glycans. Besides anticoagulant effects, certain sulfated glycans can also exhibit anti-SARS-CoV-2 properties.
Kim SB +9 more
europepmc +3 more sources
LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro
Carbohydrate Research, 2002 LaPSvS1, a highly sulfated branched (1-->3)-beta-galactan was prepared from the arabino-galactan from Larix decidua Miller by partial hydrolysis and subsequent sulfation with SO(3)-pyridine in DMF. The molecular weight was analyzed by GPC and the sulfate content was determined by ion chromatography.
Jutta, Bürgermeister +4 more
openaire +3 more sources
Octanoyl esterification of low molecular weight sulfated galactan enhances the cellular uptake and collagen expression in fibroblast cells. [PDF]
Biomed Rep, 2023 International audienceLow molecular weight sulfated galactan (LMSG) supplemented with octanoyl ester (Oct-LMSG) demonstrated superior wound healing activity compared to the unsupplemented LMSG in a fibroblast wound model.
Sakaew W +6 more
europepmc +2 more sources