Results 21 to 30 of about 1,886 (192)
Marine Drugs, 2022 The synthesis of cell-wall sulfated galactans proceeds through UDP galactose, a major nucleotide sugar in red seaweed, whilst sulfate is transported through S-transporters into algae.
Diana del Rosario-Santana +2 more
doaj +1 more source
Marine Drugs, 2022 Codium bernabei is a green alga that grows on Chilean coasts. The composition of its structural polysaccharides is still unknown. Hence, the aim of this work is to isolate and characterize the hot water extracted polysaccharide fractions.
Fabian A. Figueroa +12 more
doaj +1 more source
Marine Drugs, 2018 The anticoagulant and antithrombotic properties of three structurally correlated sea urchin-derived 3-linked sulfated α-glycans and their low molecular-weight derivatives were screened comparatively through various in vitro and in vivo methods ...
Ariana A. Vasconcelos +6 more
doaj +1 more source
Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium [PDF]
, 2016 The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity.
Fernàndez Busquets, Xavier +3 more
core +1 more source
Structure, biology, evolution, and medical importance of sulfated fucans and galactans [PDF]
Glycobiology, 2008 Sulfated fucans and galactans are strongly anionic polysaccharides found in marine organisms. Their structures vary among species, but their major features are conserved among phyla. Sulfated fucans are found in marine brown algae and echinoderms, whereas sulfated galactans occur in red and green algae, marine angiosperms, tunicates (ascidians), and ...
Vitor H, Pomin, Paulo A S, Mourão
openaire +2 more sources
Insights into the N-Sulfation Mechanism: Molecular Dynamics Simulations of the N-Sulfotransferase Domain of Ndst1 and Mutants [PDF]
, 2013 Sulfation patterns along glycosaminoglycan (GAG) chains dictate their functional role. the N-deacetylase N-sulfotransferase family (NDST) catalyzes the initial downstream modification of heparan sulfate and heparin chains by removing acetyl groups from ...
Coulson-Thomas, Vivien Jane +5 more
core +16 more sources
Frontiers in Plant Science, 2020 Seaweeds biosynthesize sulfated polysaccharides as key components of their cell walls. These polysaccharides are potentially interesting as biologically active compounds.
Marina Ciancia +3 more
doaj +1 more source
Fucose-Containing Sulfated Polysaccharides from Brown Seaweeds Inhibit Proliferation of Melanoma Cells and Induce Apoptosis by Activation of Caspase-3 in Vitro [PDF]
, 2011 Fucose-containing sulfated polysaccharides (FCSPs) extracted from seaweeds, especially brown macro-algae, are known to possess essential bioactive properties, notably growth inhibitory effects on tumor cells.
Ale, Marcel Tutor +4 more
core +1 more source
Is the antithrombotic effect of sulfated galactans independent of serpin? [PDF]
Journal of Thrombosis and Haemostasis, 2014 Sulfated galactans are polysaccharides with heterogeneous structures that frequently show anticoagulant activity. Their anticoagulant mechanisms are complex and distinct from those observed for heparin. Sulfated galactans act through a combination of effects involving serpin-dependent and serpin-independent mechanisms. Interestingly, these polymers can
A-L G, Quinderé +8 more
openaire +2 more sources
Natural Products as Source of Potential Dengue Antivirals [PDF]
, 2014 Dengue is a neglected disease responsible for 22,000 deaths each year in areas where it is endemic. To date, there is no clinically approved dengue vaccine or antiviral for human beings, even though there have been great efforts to accomplish these goals.
Adalberto da Silva +21 more
core +4 more sources