Characterization and immunomodulatory activity of sulfated galactan from the red seaweed Gracilaria fisheri. [PDF]
Polysaccharides from the red seaweed Gracilaria fisheri possess many functions, which include antioxidant, antiviral, and antibacterial activities. However, detailed data on their immunomodulatory activities are scarce. Here, we isolated sulfated galactans (SG) from G. fisheri. We found that the predominant SG from G.
Khongthong S +5 more
europepmc +3 more sources
A Repeating Sulfated Galactan Motif Resuscitates Dormant Micrococcus luteus Bacteria. [PDF]
ABSTRACT Only a small fraction of bacteria can autonomously initiate growth on agar plates. Nongrowing bacteria typically enter a metabolically inactive dormant state and require specific chemical trigger factors or signals to exit this state and to resume growth.
Böttcher T, Szamosvári D, Clardy J.
europepmc +4 more sources
Occurrence of sulfated galactans in marine angiosperms: evolutionary implications [PDF]
We report for the first time that marine angiosperms (seagrasses) possess sulfated polysaccharides, which are absent in terrestrial and freshwater plants. The structure of the sulfated polysaccharide from the seagrass Ruppia maritima was determined. It is a sulfated D-galactan composed of the following regular tetrasaccharide repeating unit: [3-beta-D ...
Rafael S, Aquino +4 more
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Is the antithrombotic effect of sulfated galactans independent of serpin? [PDF]
Sulfated galactans are polysaccharides with heterogeneous structures that frequently show anticoagulant activity. Their anticoagulant mechanisms are complex and distinct from those observed for heparin. Sulfated galactans act through a combination of effects involving serpin-dependent and serpin-independent mechanisms. Interestingly, these polymers can
A-L G, Quinderé +8 more
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Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans? [PDF]
We attempted to identify the specific structural features in sulfated galactans and sulfated fucans that confer anticoagulant activity. For this study we employed a variety of invertebrate polysaccharides with simple structures composed of well-defined units of oligosaccharides.
Mariana S, Pereira +2 more
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Figure 19. Sulfated galactan, Figure 20. Oleandrin
Figure 19. Sulfated galactan spiderchem ID : N/A Figure 20.
Adryan Fristiohady (12512725)
core +1 more source
Antiviral activity of marine sulfated glycans against pathogenic human coronaviruses
Great interest exists towards the discovery and development of broad-spectrum antivirals. This occurs due to the frequent emergence of new viruses which can also eventually lead to pandemics.
Mary Zoepfl +4 more
doaj +1 more source
Trehalose as a Possible Precursor of the Sulfated L-Galactan in the Ascidian Tunic [PDF]
Among sulfated polysaccharides, those in the tunic of ascidians are unique: their major constituent sugar is galactose, which occurs exclusively in the L-enantiomeric form. Incorporation of D-[14C]glucose into tunic slices in vitro revealed that the cells epimerize D-glucose into L-galactose during biosynthesis of the sulfated polysaccharides.
P A, Mourão, A M, Assreuy
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The number of deaths associated with cardiovascular diseases (CVD) increases every year, leading to an intense search for new compounds that may be employed as anticoagulants.
BIANCA B. COSTA +8 more
doaj +1 more source
Structure, biology, evolution, and medical importance of sulfated fucans and galactans [PDF]
Sulfated fucans and galactans are strongly anionic polysaccharides found in marine organisms. Their structures vary among species, but their major features are conserved among phyla. Sulfated fucans are found in marine brown algae and echinoderms, whereas sulfated galactans occur in red and green algae, marine angiosperms, tunicates (ascidians), and ...
Vitor H, Pomin, Paulo A S, Mourão
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