Results 111 to 120 of about 45,956 (313)
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
The experiment was established in the spring 1999 on lessive soil developed from light boulder clay. Apple trees of Golden Delicious cv. on M.26 rootstock were planted in 3.5 × 1.2 m (2381 trees·ha-1) spacing. Research involved the effect of diversified
Adam Szewczuk +2 more
doaj
[1] Dehydration/rehydration experiments were conducted on pure Mg-sulfates and mixtures of epsomite with Ca-sulfates, Fe-sulfates, Fe-oxide, and Fe-hydroxide.
John J Freeman +2 more
core
The C1s activity was measured in the presence of C1-INH and test compound (final concentration: a) 0.625 μg/ml b) 0.3125–0.625–1.25–6.25 μg/ml) by a chromogenic substrate assay. The C1-INH potentiation (%) is the increase in C1s inhibition in presence of
Susanne Alban (2339212) +2 more
core +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Revisiting three minerals from Cioclovina Cave (Romania)
Cioclovina Cave in Romania’s Southern Carpathians is a world-renowned cave site for its paleontological, anthropological, andmineralogical (type locality of ardealite) finds.
Onac Bogdan P. +4 more
doaj
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Chondroitin sulfates and Heparins: Structure, properties, role and related analytical approaches
Chondroitin sulfates and Heparins: Structure, properties, role and related analytical ...
VOLPI, Nicola
core

