Results 31 to 40 of about 8,975 (219)

Biophysical Features of Bacillithiol, the Glutathione Surrogate of Bacillus subtilis and other Firmicutes [PDF]

, 2013
Bacillithiol (BSH) is the major low-molecular-weight (LMW) thiol in many low-G+C Gram-positive bacteria (Firmicutes). Evidence now emerging suggests that BSH functions as an important LMW thiol in redox regulation and xenobiotic detoxification, analogous
Arbach, Miriam, Groom, Murree, Hamilton, Chris J., Macdonald, Colin J., Roberts, Alexandra A., Sharma, Sunil V.   +5 more
core   +1 more source

Identification of Sulfenylated Cysteines in Arabidopsis thaliana Proteins Using a Disulfide-Linked Peptide Reporter

Frontiers in Plant Science, 2020
In proteins, hydrogen peroxide (H2O2) reacts with redox-sensitive cysteines to form cysteine sulfenic acid, also known as S-sulfenylation. These cysteine oxidation events can steer diverse cellular processes by altering protein interactions, trafficking,
Bo Wei, Bo Wei, Bo Wei, Bo Wei, Bo Wei, Patrick Willems, Patrick Willems, Jingjing Huang, Jingjing Huang, Caiping Tian, Jing Yang, Joris Messens, Joris Messens, Joris Messens, Frank Van Breusegem, Frank Van Breusegem   +15 more
doaj   +1 more source

The role of peroxiredoxins in cancer [PDF]

, 2017
Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite.
CAPALBO, CARLO, COPPA, Anna, D'INZEO, SONIA, GIANNINI, Giuseppe, NICOLUSSI, Arianna   +4 more
core   +1 more source

Thermal degradation, antioxidant and antimicrobial activity of the synthesized allicin and allicin incorporated in gel [PDF]

Hemijska Industrija, 2010
The main carriers of the pharmacological activity of garlic (Allium sativum L.) are organic sulfur compounds, the most important among them being allicin, a sulfenic acid thioester, or allylthiosulfonate.
Ilić Dušica P., Nikolić Vesna D., Nikolić Ljubiša B., Stanković Mihajlo Z., Stanojević Ljiljana P.   +4 more
doaj   +1 more source

The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function

Antioxidants, 2018
Cysteine and methionine residues are the amino acids most sensitive to oxidation by reactive oxygen species. However, in contrast to other amino acids, certain cysteine and methionine oxidation products can be reduced within proteins by dedicated ...
Sofia Lourenço dos Santos, Isabelle Petropoulos, Bertrand Friguet   +2 more
doaj   +1 more source

The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury

Biomolecules, 2023
Vitamin C (ascorbic acid; AA) and copper (Cu2+) are well used supplements with many health-promoting actions. However, when they are used in combination, the Fenton reaction occurs, leading to the formation of highly reactive hydroxyl radicals.
Rui Jiang, Yang Sui, Jingru Hong, Manabu Niimi, Qiaojing Yan, Zhuheng Shi, Jian Yao   +6 more
doaj   +1 more source

Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding

Nature Communications, 2016
Protein S-sulfenylation is a posttranslational modification that can act as a sensor of redox oxidative stress. Here the authors show that, following mechanical unfolding, sulfenic acid drives disulfide bond reformation and guides non-enzymatic oxidative
Amy E. M. Beedle, Steven Lynham, Sergi Garcia-Manyes   +2 more
doaj   +1 more source

Characterization of Polysulfides, Polysulfanes, and Other Unique Species in the Reaction between GSNO and H₂S

Molecules, 2019
Glutathione-based products, GSnX, of the reaction of hydrogen sulfide, H2S, S-nitroso glutathione, and GSNO, at varied stoichiometries have been analyzed by liquid chromatography high-resolution mass spectrometry (LC-HRMS) and chemical trapping ...
Murugaeson R Kumar, Patrick J Farmer
doaj   +1 more source

Copper-sulfenate complex from oxidation of a cavity mutant of Pseudomonas aeruginosa azurin [PDF]

, 2014
Metal-sulfenate centers are known to play important roles in biology and yet only limited examples are known due to their instability and high reactivity.
Hadt, Ryan G., Lu, Yi, Nilges, Mark J., Sieracki, Nathan A., Solomon, Edward I., Sun, Furong, Tian, Shiliang, Woertink, Julia S., Zhang, Jun-Long   +8 more
core   +2 more sources

Identification of dimedone-trapped sulfenylated proteins in plants under stress

Biochemistry and Biophysics Reports, 2017
In stressed plants, the reactive oxygen species (ROS) levels rise. Key to ROS signaling research are detection and identification of the protein cysteine sulfenylation (-SOH), the ROS-mediated oxidative product of a thiol (-SH).
Salma Akter, Sebastien Carpentier, Frank Van Breusegem, Joris Messens   +3 more
doaj   +1 more source