Results 61 to 70 of about 8,975 (219)

On‐Demand Chemically Degradable Hydrogels for Biological Applications

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
This review explores the mechanisms and kinetics of chemically induced on‐demand degradation in hydrogels designed for painless dressing removal and traceless dissolution across various biological applications. Covalent bond cleavage and noncovalent disruption triggers are compared, highlighting opportunities for load‐bearing scaffolds with faster ...
Xinyi Sheng, Justin Kim
wiley   +1 more source

Ozone Oxidizes Glutathione to a Sulfonic Acid [PDF]

, 2009
Biosurfaces are universally covered with fluid microfilms containing reduced glutathione (GSH) and other antioxidants whose putative roles include the detoxification of ambient ozone (O_3).
Colussi, A. J., Enami, Shinichi, Hoffmann, M. R.   +2 more
core   +1 more source

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

Small, Volume 22, Issue 15, 12 March 2026.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt, Meike Heuser, Paul Schulan, Lea Miebach, Alice Martinet, Marcus Frank, Kristian Wende, Sander Bekeschus   +7 more
wiley   +1 more source

Redox regulation of methylthioadenosine phosphorylase in liver cells: molecular mechanism and functional implications [PDF]

, 2008
MTAP (5'-methylthioadenosine phosphorylase) catalyses the reversible phosphorolytic cleavage of methylthioadenosine leading to the production of methylthioribose-1-phosphate and adenine.
Avila, M.A. (Matías Antonio), Corrales, F.J. (Fernando José), Fernandez-Irigoyen, J. (Joaquín), Latasa, M.U. (María Ujué), Muñoz, J. (Javier), Prieto, J. (Jesús), Sanchez-del-Pino, M.M. (Manuel M.), Sanchez-Quiles, V. (Virginia), Santamaria, E. (Enrique), Santamaria, M. (Mónica), Valero, M.L. (María L.)   +10 more
core   +1 more source

Sulfenic acids as reactive intermediates in xenobiotic metabolism [PDF]

Archives of Biochemistry and Biophysics, 2011
Sulfenic acid reactive intermediates are formed during the oxidation of cysteine residues of proteins and play key roles in enzyme catalysis, redox homeostasis and regulation of cell signalling. However few data are presently available on the formation and fate of sulfenic acids as reactive intermediates during the metabolism of xenobiotics.
Daniel, Mansuy, Patrick M, Dansette
openaire   +2 more sources

Crystal structure of plant γ‐glutamyl peptidase 1: implications for sulfur metabolism and secondary metabolite biosynthesis

The FEBS Journal, Volume 293, Issue 5, Page 1400-1414, March 2026.
The crystal structures of Arabidopsis thaliana γ‐glutamyl peptidase 1 (GGP1), including the covalent intermediate state, were determined. GGP1 is involved in both glutathione degradation in the primary metabolism and glutathione conjugate processing in the secondary metabolism of glucosinolate and camalexin biosynthesis.
Kosei Sone, Takehiro Ito, Hibiki Sawada, Chihaya Yamada, Toma Kashima, Akimasa Miyanaga, Naoko Ohkama‐Ohtsu, Shinya Fushinobu   +7 more
wiley   +1 more source

Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology

Frontiers in Pharmacology, 2014
The perception of reactive oxygen species (ROS) has evolved over the past decade from agents of cellular damage to secondary messengers which modify signaling proteins in physiology and the disease state (e.g. cancer).
Revati eWani, Asako eNagata, Brion William Murray   +2 more
doaj   +1 more source

OH-Radical Oxidation of Lung Surfactant Protein B on Aqueous Surfaces [PDF]

, 2018
Air pollutants generate reactive oxygen species on lung surfaces. Here we report how hydroxyl radicals (·OH) injected on the surface of water react with SP-B_(1–25), a 25-residue polypeptide surrogate of human lung surfactant protein B.
Colussi, Agustín J., Enami, Shinichi
core   +1 more source

Localized redox relays as a privileged mode of cytoplasmic hydrogen peroxide signaling [PDF]

, 2017
Hydrogen peroxide (H2O2) is a key signaling agent. Its best characterized signaling actions in mammalian cells involve the early oxidation of thiols in cytoplasmic phosphatases, kinases and transcription factors.
Abranches, Pedro, Bayani, Anahita, Salvador, Armindo, Sampaio dos Aidos, Fernando, Travasso, Rui D.M.   +4 more
core   +3 more sources

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, Volume 36, Issue 14, 16 February 2026.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source