Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang+5 more
wiley +1 more source
Impacts of Various Reheating Methods on Crispy Chicken: Physicochemical Properties, Oxidation and Flavor Profiles. [PDF]
Ren X, Wang C, Wang X, Su T, Yu Y.
europepmc +1 more source
S2 treatment regulated the flavonoid and histidine metabolism pathways of Jingu 21, reduced the protein content, increased the fat and starch contents, and decreased the peak viscosity and breakdown value. S2 treatment regulated the Stilbenoid, diarylheptanoid, and gingerol pathway of Jingu 40, and S3 treatment activated the tyrosine metabolic pathway ...
Shu Wang+5 more
wiley +1 more source
Effect of Low-Temperature Plasma Sterilization on the Quality of Pre-Prepared Tomato-Stewed Beef Brisket During Storage: Microorganism, Freshness, Protein Oxidation and Flavor Characteristics. [PDF]
Shi Q+6 more
europepmc +1 more source
The microbiologist's guide to metaproteomics
Metaproteomics within the multi‐omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs), mapping protein–protein interactions (PPIs), and localizing proteins.
Tim Van Den Bossche+31 more
wiley +1 more source
Differences in storage stability of cow's milk-based and goat's milk-based infant formulas. [PDF]
Wan L+9 more
europepmc +1 more source
We present an innovative methodology that integrates core enzyme identification, protein structural characterization, regulator virtual screening, and functional validation to achieve precise microbiome functional regulation. As a proof of concept, we focused on the regulation of urea decomposition by the rumen microbiota in ruminants. This methodology
Shengguo Zhao+9 more
wiley +1 more source
Enhancing the Textural Properties of Tibetan Pig Sausages via <i>Zanthoxylum bungeanum</i> Aqueous Extract: Polyphenol-Mediated Quality Improvements. [PDF]
Huang J+5 more
europepmc +1 more source
ABSTRACT Background Intervertebral disc (IVD) degeneration (IDD) is the main contributor to chronic low back pain (LBP), the leading cause of disability worldwide, with a significant impact on the quality of life and health of common people. The etiology of IDD is still unclear, but it has been largely demonstrated the crucial role of inflammation and ...
Laura Guarnaccia+20 more
wiley +1 more source
Protein oxidation and its effect on functional properties of livestock products during the processing and storage: A review. [PDF]
Wang J+6 more
europepmc +1 more source