Results 241 to 250 of about 50,150 (276)
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Reaction of malformin with sulfhydryl compounds
Phytochemistry, 1970Abstract Malformin reacts with the sulfhydryl compounds, cysteine and β-mercaptoethanol, to form an insoluble 1:1 addition product. This reaction may explain the ability of thiol compounds to inhibit the activity of malformin and suggests reaction of malformin with thiol compounds in vivo .
Shinobu Iriuchijima, Roy W. Curtis
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Giant axonal neuropathy: studies with sulfhydryl donor compounds
Journal of the Neurological Sciences, 1990Giant axonal neuropathy (GAN) is a disorder characterized pathologically by distal neurofilament-filled bulbous swellings in axons, and widespread collection of intermediate filaments, including masses of vimentin filaments in cultured skin fibroblasts.
R, Tandan, W G, Bradley, M J, Fillyaw
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Sulfhydryl Compounds as Thermosensitizers
1988The cytotoxic effects of a number of widely used chemotherapeutic agents have been reported to be enhanced by heat (Hahn 1979; Hahn and Li 1982). The exact mechanism of this enhancement is not fully understood and might differ with the various compounds. Thermosensitization by sulfhydryl compounds in vitro has been observed by Kapp and Hahn (1979).
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Bioanalytical considerations for compounds containing free sulfhydryl groups
Biomedical Chromatography, 2003AbstractThiol‐containing compounds pose bioanalytical challenge in several dimensions due to extreme reactivity of the sulfhydryl group. The development of robust bioanalytical methodology for thiol groups should address the aspects of adequate stabilization in the biological matrix and selectivity considerations.
Nuggehally R, Srinivas +1 more
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Incorporation of sulfhydryl compounds into melanins in vitro
Biochimica et Biophysica Acta (BBA) - General Subjects, 1988Cysteine is known to be involved in pheomelanin synthesis. Available evidence, however, indicates that glutathione may also play an important role in melanogenesis. This in vitro study clarifies how cysteine and glutathione participate in melanogenesis.
S, Ito, Y, Imai, K, Jimbow, K, Fujita
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Enzymic methylation of foreign sulfhydryl compounds
Biochimica et Biophysica Acta, 1961Abstract A new transmethylating enzyme system in mammalian tissues, catalyzing methyl transfer from S-adenosylmethionine to sulfhydryl compounds, has been studied. A series of “nonphysiological” sulfhydryl compounds (BAL, mercaptoethanol, O-methyl-mercaptoethanol, mercaptoacetic acid, β-mercaptoproprionic acid, methymercaptan and hydrogen sulfide ...
Jon Bremer, David M. Greenberg
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The reduction of experimentally induced inflammation by sulfhydryl compounds
Biochemical Pharmacology, 1967Abstract The sulfhydryl compounds acetylcysteine and acetylpenicillamine were found to reduce the severity of induced dermal inflammation in rabbits when the compounds were administered in repeated doses. Treatment with acetylcysteine and salicylate given concomitantly resulted in an anti-inflammatory response which was equal to that obtained with ...
K R, Bailey, A L, Sheffner
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Penaeus vannamei protease activating mechanism of sulfhydryl reducing compounds
International Journal of Biological Macromolecules, 2018For the very first time, protease enzyme from Penaeus vannamei was investigated for its activation with thiol reductant compounds. The mechanism by which sulfhydryl reductant compounds enhances the activity of P. vannamei protease still remains unclear. In this study, it was discovered that thiol-reactive compounds increase P.
Morteza Bahrami, Ahmad Homaei
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The Inhibition of Metabolic Oxalate Production by Sulfhydryl Compounds
Journal of Urology, 1991A number of sulfhydryl compounds were shown to inhibit CO2 and oxalate formation from glyoxylate by rat liver homogenates and hepatocytes. The most significant inhibition occurred with cysteine and this inhibition was concentration-dependent. In rats made hyperoxaluric by administering ethylene glycol in their drinking water, daily intraperitoneal ...
R, Bais, A M, Rofe, R A, Conyers
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Adverse effects profile of sulfhydryl compounds in man
The American Journal of Medicine, 1986Many of the adverse reactions produced by penicillamine and other compounds with an active sulfhydryl group form a distinctive pattern when viewed as a class. Alterations in taste perception, mucocutaneous lesions, proteinuria due to immune-complex membranous glomerulopathy, and pemphigus are adverse reactions that have been encountered with all of the
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