Results 251 to 260 of about 3,705,484 (314)
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Products of the reaction of selenite with intracellular sulfhydryl compounds
Biological Trace Element Research, 1991The usual first step in the intracellular metabolism of exogenous selenite is its chemical reaction with glutathione to form selenodiglutathione (1). We have investigated whether selenite also reacts intracellularly with other SH compounds. HeLa cells were exposed to [75Se]selenite and lysed with SDS.
G D, Frenkel, D, Falvey, C, MacVicar
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Molecular Pharmacology, 1988
Previous studies have demonstrated that selenite inhibits cellular DNA synthesis. We have now found that endogenous cellular sulfhydryl compounds are involved in this effect of selenite.
Gerald D. Frenkel, D. Falvey
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Previous studies have demonstrated that selenite inhibits cellular DNA synthesis. We have now found that endogenous cellular sulfhydryl compounds are involved in this effect of selenite.
Gerald D. Frenkel, D. Falvey
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In vivo depression of hepatic succinoxidase by sulfhydryl compounds
Biochemical and Biophysical Research Communications, 1971Abstract Thioglycolate injected i.v. in dosages of 50 mg/kg, significantly depressed hepatic succinoxidase in immature rats of either sex and adult males whereas, about a five-fold excess was required to elicit a significant response in adult females. Ovariectomy increased and estradiol pretreatment, decreased the sensitivity to thioglycolate.
S, Bakshy, L L, Gershbein
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The Inhibition of Metabolic Oxalate Production by Sulfhydryl Compounds
Journal of Urology, 1991A number of sulfhydryl compounds were shown to inhibit CO2 and oxalate formation from glyoxylate by rat liver homogenates and hepatocytes. The most significant inhibition occurred with cysteine and this inhibition was concentration-dependent. In rats made hyperoxaluric by administering ethylene glycol in their drinking water, daily intraperitoneal ...
R, Bais, A M, Rofe, R A, Conyers
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The reduction of experimentally induced inflammation by sulfhydryl compounds
Biochemical Pharmacology, 1967Abstract The sulfhydryl compounds acetylcysteine and acetylpenicillamine were found to reduce the severity of induced dermal inflammation in rabbits when the compounds were administered in repeated doses. Treatment with acetylcysteine and salicylate given concomitantly resulted in an anti-inflammatory response which was equal to that obtained with ...
K R, Bailey, A L, Sheffner
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The effect of sulfhydryl compounds on sister-chromatid exchanges
Mutation Research/Genetic Toxicology, 1980We examined the SH compounds glutathione (GSH), cysteine (CYS), cysteamine (MEA) and 2-mercaptoethanol (MET) with regard to their capacity for inducing SCEs. Whereas cysteamine and 2-mercaptoethanol increased the SCE frequency, this did not happen with glutathione and cysteine.
G, Speit, M, Wolf, W, Vogel
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The Regulatory Role of Sulfhydryl Compounds in Melanogenesis
Pigment Cell Research, 1988Since the discovery in 1967 of the phaeomelanin pathway the regulatory role of sulfhydryl compounds in epidermal melanin pigmentation has been a major focus in pigment cell research. The current state of knowledge in the field is briefly discussed, with special reference to some recent studies extending the possible targets of sulfhydryl compounds to ...
PROTA, GIUSEPPE +2 more
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Response of sulfhydryl compounds in subcells of Cladophora rupestris under Pb stress
Environmental science and pollution research international, 2020Qiu-yu Chen +7 more
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Toxicity of sulfhydryl compounds to cultured human lymphocytes
Experimental Cell Research, 1970Abstract The toxicity of cysteine metabolites for cultured human lymphocytes decreases with proximity in the metabolic pathways to the usual organic excretory product, taurine. Polyploidy induction also roughly parallels toxicity.
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In Vitro Reduction of Tetrazolium Indicators by Sulfhydryl Compounds
Stain Technology, 1954There was considerable variation between the sulfhydryl induced in vitro reduction of the oxidation-reduction indicators (2,3,5-triphenyltetrazolium chloride, 2,3-diphenyl 5-methyl tetrazolium chloride, neotetrazolium chloride, neotetrazolium phosphate-2B, blue tetrazolium, tetrazolium violet, potassium tellurite, methylene blue, and resazurin).
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