The role of glutamate oxaloacetate transaminases in sulfite biosynthesis and H2S metabolism
Redox Biology, 2021 Molybdenum cofactor deficiency and isolated sulfite oxidase deficiency are two rare genetic disorders that are caused by impairment of the mitochondrial enzyme sulfite oxidase.
Anna-Theresa Mellis +8 more
doaj +3 more sources
Molecular Basis of Sulfite Oxidase Deficiency from the Structure of Sulfite Oxidase [PDF]
Cell, 1997 The molybdenum-containing enzyme sulfite oxidase catalyzes the conversion of sulfite to sulfate, the terminal step in the oxidative degradation of cysteine and methionine. Deficiency of this enzyme in humans usually leads to major neurological abnormalities and early death.
Kisker, Caroline +7 more
openaire +4 more sources
Sulfite oxidase deficiency in a newborn
Journal of the Belgian Society of Radiology, 2014 Isolated sulfite oxidase deficiency is a rare, autosomal recessive disease with a very poor prognosis. This condition usually presents in the neonatal period and is mainly characterized by neurological abnormalities, including refractory seizures ...
H Westerlinck +3 more
doaj +5 more sources
Stable clinical course in three siblings with late-onset isolated sulfite oxidase deficiency: a case series and literature review [PDF]
BMC Pediatrics, 2019 Background Isolated sulfite oxidase deficiency (ISOD) is an autosomal recessive disorder caused by a deficiency of sulfite oxidase, which is encoded by the sulfite oxidase gene (SUOX).
Maoqiang Tian +7 more
doaj +2 more sources
The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia [PDF]
Nature Communications, 2018 In Drosophila, ensheathing glia encase the neuropil but their function is not well understood. Here the authors show a surprising role of ensheathing glia in regulating glutamate homeostasis and locomotion which is controlled by the sulfite oxidase ...
Nils Otto +14 more
doaj +2 more sources
Sulfite Oxidase Activity Is Essential for Normal Sulfur, Nitrogen and Carbon Metabolism in Tomato Leaves [PDF]
Plants, 2015 Plant sulfite oxidase [SO; E.C.1.8.3.1] has been shown to be a key player in protecting plants against exogenous toxic sulfite. Recently we showed that SO activity is essential to cope with rising dark-induced endogenous sulfite levels in tomato plants ...
Galina Brychkova +8 more
doaj +2 more sources
Overexpression of the Maize Sulfite Oxidase Increases Sulfate and GSH Levels and Enhances Drought Tolerance in Transgenic Tobacco [PDF]
Frontiers in Plant Science, 2018 Sulfite oxidase (SO) plays a pivotal role in sulfite metabolism. In our previous study, sulfite-oxidizing function of the SO from Zea mays (ZmSO) was characterized. To date, the knowledge of ZmSO’s involvement in abiotic stress response is scarce.
Zongliang Xia +4 more
doaj +2 more sources
Severe isolated sulfide oxidase deficiency with a novel mutation
The Turkish Journal of Pediatrics, 2021 Background. Isolated sulfite oxidase deficiency (ISOD), caused by mutations in SUOX gene, is an autosomal recessive disease manifesting with early onset seizures, developmental delay, microcephaly, and spasticity.
Meriç Ergene +6 more
doaj +1 more source
Overexpression of a maize sulfite oxidase gene in tobacco enhances tolerance to sulfite stress via sulfite oxidation and CAT-mediated H2O2 scavenging. [PDF]
PLoS ONE, 2012 Sulfite oxidase (SO) plays an important role in sulfite metabolism. To date, the molecular mechanisms of sulfite metabolism in plants are largely unknown.
Zongliang Xia +5 more
doaj +1 more source
Cells, 2023 Sulfite predominantly accumulates in the brain of patients with isolated sulfite oxidase (ISOD) and molybdenum cofactor (MoCD) deficiencies. Patients present with severe neurological symptoms and basal ganglia alterations, the pathophysiology of which is
Nícolas Manzke Glänzel +9 more
doaj +1 more source