Results 51 to 60 of about 28,271 (292)

Rings in the Extreme: PCNA Interactions and Adaptations in the Archaea [PDF]

open access: yes, 2012
Biochemical and structural analysis of archaeal proteins has enabled us to gain great insight into many eukaryotic processes, simultaneously offering fascinating glimpses into the adaptation and evolution of proteins at the extremes of life. The archaeal
Bunting, KA, Winter, JA
core   +2 more sources

Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile

open access: yesNature Communications, 2018
Only a few archaeal filamentous viruses have been structurally characterized. Here the authors describe the membrane-enveloped Sulfolobus filamentous virus 1 that infects Sulfolobus shibatae and present its 3.7 Å resolution cryo-EM structure, which ...
Ying Liu   +7 more
doaj   +1 more source

Biological Membranes in Extreme Conditions: Simulations of Anionic Archaeal Tetraether Lipid Membranes. [PDF]

open access: yesPLoS ONE, 2016
In contrast to the majority of organisms that have cells bound by di-ester phospholipids, archaeal membranes consist of di- and tetraether phospholipids.
Luis Felipe Pineda De Castro   +2 more
doaj   +1 more source

Surface resistance to SSVs and SIRVs in pilin deletions of Sulfolobus islandicus

open access: yesMolecular Microbiology, 2019
Characterizing the molecular interactions of viruses in natural microbial populations offers insights into virus–host dynamics in complex ecosystems. We identify the resistance of Sulfolobus islandicus to Sulfolobus spindle‐shaped virus (SSV9) conferred ...
Elizabeth F. Rowland   +3 more
semanticscholar   +1 more source

Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity. [PDF]

open access: yes, 2006
The archaeal/eukaryotic proliferating cell nuclear antigen (PCNA) toroidal clamp interacts with a host of DNA modifying enzymes, providing a stable anchorage and enhancing their respective processivities.
Andrew S. Doré   +48 more
core   +4 more sources

Architecture and modular assembly of Sulfolobus S-layers revealed by electron cryotomography

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Many bacteria and most archaea are enveloped in S-layers, protective lattices of proteins that are among the most abundant on earth. S-layers define both the cell’s shape and periplasmic space, and play essential roles in cell division ...
L. Gambelli   +7 more
semanticscholar   +1 more source

Calditol-linked membrane lipids are required for acid tolerance in Sulfolobus acidocaldarius

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance It is thought that the distinct ether lipid membranes of archaea allow them to thrive in environmental extremes. However, it has been difficult to demonstrate this physiological role directly.
Z. Zeng   +4 more
semanticscholar   +1 more source

Prediction of mutations on structure primase of the archaeon Sulfolobus solfataricus

open access: yesActa Scientiarum: Biological Sciences, 2017
  All living organisms need a DNA replication mechanism and it has been conserved in the three domains of life throughout evolutionary process. Primase is the enzyme responsible for synthesizing de novo RNA primers in DNA replication. Archaeo-Eukaryotic
Eden Silva e Souza   +1 more
doaj   +1 more source

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

open access: yesAngewandte Chemie, Volume 137, Issue 36, September 1, 2025.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar   +15 more
wiley   +2 more sources

pTC Plasmids from Sulfolobus Species in the Geothermal Area of Tengchong, China: Genomic Conservation and Naturally-Occurring Variations as a Result of Transposition by Mobile Genetic Elements

open access: yesLife, 2015
Plasmids occur frequently in Archaea. A novel plasmid (denoted pTC1) containing typical conjugation functions has been isolated from Sulfolobus tengchongensis RT8-4, a strain obtained from a hot spring in Tengchong, China, and characterized.
Xiaoyu Xiang   +3 more
doaj   +1 more source

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