Results 61 to 70 of about 13,977 (211)
ChemistryOpen, Volume 15, Issue 7, July 2026.Several factors including hydrophobic packing, electrostatic interactions and hydrogen bonding influence thermostability of proteins. Mechanisms of thermal adaptation were investigated via structural and mutational studies. Stability predictions were enhanced by combining thermodynamic data with ML‐based computer models for protein engineering ...
Sermarajan Arunachalam +2 more
wiley +1 more source
Journal of Microbiology and Biotechnology, 2015 A Sulfolobus-E. coli shuttle vector for an efficient expression of the target gene in S. acidocaldarius strain was constructed. The plasmid-based vector pSM21 and its derivative pSM21N were generated based on the pUC18 and Sulfolobus cryptic plasmid pRN1. They carried the S.
Sungmin, Hwang +3 more
openaire +2 more sources
Acta Biochimica et Biophysica Sinica, 2022 Apurinic/apyrimidic (AP) sites are severe DNA damages and strongly block DNA extension by major DNA polymerases. Y-family DNA polymerases possess a strong ability to bypass AP sites and continue the DNA synthesis reaction, which is called translesion ...
Wang Weiwei +7 more
doaj +1 more source
Environmental Microbiology, Volume 28, Issue 7, July 2026.A novel polyP‐degrading enzyme with an activity differing from those currently known was found in Haloferax volcanii, conferring the ability for this microbe to grow on extracellular polyP. These findings further our understanding of the potential ecological roles of polyP and how archaea metabolise this essential biopolymer.
Jack W. F. Nicholls +4 more
wiley +1 more source
Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas
Nature Communications, 2019 Type III CRISPR-Cas RNases from the Csm and Csx families are activated by cyclic oligoadenylates (cOA). Here the authors present the cOA bound Sulfolobus islandicus Csx1 structure, which forms a hexamer and reveal an allosteric mechanism for the ...
Rafael Molina +8 more
doaj +1 more source
The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor
Nature Communications, 2017 Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase ...
Thomas Fouqueau +5 more
doaj +1 more source
Alterations of the transcriptome of Sulfolobus acidocaldarius by exoribonuclease aCPSF2.
PLoS ONE, 2013 Recent studies identified a 5´ to 3´ exoribonuclease termed Sso-RNase J in the crenarchaeon Sulfolobus solfataricus (Sso), which has been reclassified to the aCPSF2 (archaeal cleavage and polyadenylation specificity factor 2) group of β-CASP proteins. In
Birgit Märtens +7 more
doaj +1 more source
Electronic Journal of Biotechnology, 2017 Background: Sulphur-oxidizing microorganisms are widely used in the biofiltration of total reduced sulphur compounds (odorous and neurotoxic) produced by industries such as the cellulose and petrochemical industries, which include high-temperature ...
Emky Valdebenito-Rolack +4 more
doaj +1 more source
TopA, the Sulfolobus solfataricus topoisomerase III, is a decatenase
Nucleic Acids Research, 2017 DNA topoisomerases are essential enzymes involved in all the DNA processes and among them, type IA topoisomerases emerged as a key actor in the maintenance of genome stability.
Anna H. Bizard +7 more
semanticscholar +1 more source
Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Advanced NanoBiomed Research, Volume 6, Issue 6, June 2026.Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
wiley +1 more source