Results 61 to 70 of about 14,486 (168)

Molecular Adaptations of Thermophilic Proteins—From Mechanistic Understanding to Machine Learning Approaches

open access: yesChemistryOpen, Volume 15, Issue 7, July 2026.
Several factors including hydrophobic packing, electrostatic interactions and hydrogen bonding influence thermostability of proteins. Mechanisms of thermal adaptation were investigated via structural and mutational studies. Stability predictions were enhanced by combining thermodynamic data with ML‐based computer models for protein engineering ...
Sermarajan Arunachalam   +2 more
wiley   +1 more source

A Novel Polyphosphate‐Degrading Enzyme Confers Growth on Exogenous Polyphosphate in the Archaeon Haloferax volcanii

open access: yesEnvironmental Microbiology, Volume 28, Issue 7, July 2026.
A novel polyP‐degrading enzyme with an activity differing from those currently known was found in Haloferax volcanii, conferring the ability for this microbe to grow on extracellular polyP. These findings further our understanding of the potential ecological roles of polyP and how archaea metabolise this essential biopolymer.
Jack W. F. Nicholls   +4 more
wiley   +1 more source

Genetic engineering of sulfur-degrading Sulfolobus. Final technical report, September 1, 1990--August 31, 1991

open access: yes, 1991
The objectives of the proposed research is to first establish a plasmid-mediated genetic transformation system for the sulfur degrading Sulfolobus, and then to clone and overexpress the genes encoding the organic-sulfur-degrading enzymes from Sulfolobus-
Ho, N. W. Y.
core   +1 more source

Bioleaching of Molybdenum by Two New Thermophilic Strains Isolated and Characterized [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2017
This study involves the isolation and characterization of a bacterial strain capable of bioleaching molybdenum ore. Bacterial growth was observed when rock sample was incubated in 9K at 70 ºC.
Mahshid Roshani   +5 more
doaj  

The essential genome of the crenarchaeal model Sulfolobus islandicus

open access: yesNature Communications, 2018
Sulfolobus islandicus is a model organism within the TACK superphylum of the Archaea. Here, the authors perform a genome-wide analysis of essential genes in this organism, show that the proteinaceous S-layer is not essential, and explore potential stages
Changyi Zhang   +4 more
doaj   +1 more source

Structural basis for inhibition of an archaeal CRISPR–Cas type I-D large subunit by an anti-CRISPR protein

open access: yesNature Communications, 2020
In type I-D CRISPR–Cas systems, the nuclease and helicase activities are carried out by separate subunits. The crystal structure of Sulfolobus islandicus type I-D large subunit Cas10d, containing a nuclease domain, reveals unusual architecture.
M. Cemre Manav   +5 more
doaj   +1 more source

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 6, June 2026.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr   +9 more
wiley   +1 more source

Exploring surface structures

open access: yeseLife
The surface layer of Sulfolobus acidocaldarius consists of a flexible but stable outer protein layer that interacts with an inner, membrane-bound protein.
Bernhard Schuster
doaj   +1 more source

A genetic study of SSV1, the prototypical fusellovirus.

open access: yesFrontiers in Microbiology, 2012
Viruses of thermophilic Archaea are unique in both their structures and genomic sequences. The most widespread and arguably best studied are the lemon-shaped fuselloviruses.
Eric eIverson, Kenneth eStedman
doaj   +1 more source

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

open access: yesFood Bioengineering, Volume 5, Issue 2, Page 220-243, June 2026.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang   +7 more
wiley   +1 more source

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