Results 81 to 90 of about 21,408 (208)

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

The essential genome of the crenarchaeal model Sulfolobus islandicus

open access: yesNature Communications, 2018
Sulfolobus islandicus is a model organism within the TACK superphylum of the Archaea. Here, the authors perform a genome-wide analysis of essential genes in this organism, show that the proteinaceous S-layer is not essential, and explore potential stages
Changyi Zhang   +4 more
doaj   +1 more source

The physicist's guide to one of biotechnology's hottest new topics: CRISPR-Cas

open access: yes, 2018
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) constitute a multi-functional, constantly evolving immune system in bacteria and archaea cells.
Bonomo, Melia E., Deem, Michael W.
core   +1 more source

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity [PDF]

open access: yes, 2013
hSSB1 is a recently discovered single-stranded DNA binding protein that is essential for efficient repair of DNA double-strand breaks (DSBs) by the homologous recombination pathway.
Bain, Amanda   +7 more
core   +1 more source

An exosome‐like complex in Sulfolobus solfataricus [PDF]

open access: yesEMBO reports, 2003
We present the first experimental evidence for the existence of an exosome‐like protein complex in Archaea. In Eukarya, the exosome is essential for many pathways of RNA processing and degradation. Co‐immunoprecipitation with antibodies directed against the previously predicted Sulfolobus solfataricus
Evguenieva-Hackenberg, E.   +4 more
openaire   +3 more sources

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

open access: yesAdvanced Science, Volume 13, Issue 18, 27 March 2026.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding   +5 more
wiley   +1 more source

DNA Binding in High Salt: Analysing the Salt Dependence of Replication Protein A3 from the Halophile Haloferax volcanii [PDF]

open access: yes, 2012
Halophilic archaea maintain intracellular salt concentrations close to saturation to survive in high-salt environments and their cellular processes have adapted to function under these conditions.
Bunting, KA, Patoli, B, Winter, JA
core   +2 more sources

Microbial regulation of global macroalgal blooms (green tides): From holobiont interactions to bloom dynamics and biogeochemistry

open access: yesLimnology and Oceanography Letters, Volume 11, Issue 2, March 2026.
Abstract Green tides caused by Ulva species have become one of the most serious marine ecological disasters, now impacting many coastal nations around the world. Although climatic and environmental drivers of these macroalgal blooms are well recognized, growing evidence identifies Ulva‐associated microbiota as potential pivotal regulators of bloom ...
Zhangyi Xia   +6 more
wiley   +1 more source

Bioleaching of Molybdenum by Two New Thermophilic Strains Isolated and Characterized [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2017
This study involves the isolation and characterization of a bacterial strain capable of bioleaching molybdenum ore. Bacterial growth was observed when rock sample was incubated in 9K at 70 ºC.
Mahshid Roshani   +5 more
doaj  

A genetic study of SSV1, the prototypical fusellovirus.

open access: yesFrontiers in Microbiology, 2012
Viruses of thermophilic Archaea are unique in both their structures and genomic sequences. The most widespread and arguably best studied are the lemon-shaped fuselloviruses.
Eric eIverson, Kenneth eStedman
doaj   +1 more source

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