Structural–Functional Relationship of the Ribonucleolytic Activity of aIF5A from Sulfolobus solfataricus [PDF]
Biomolecules, 2022 The translation factor IF5A is a highly conserved protein playing a well-recognized and well-characterized role in protein synthesis; nevertheless, some of its features as well as its abundance in the cell suggest that it may perform additional functions
Alice Romagnoli +8 more
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Insights Into the Binding Mechanism of GC7 to Deoxyhypusine Synthase in Sulfolobus solfataricus: A Thermophilic Model for the Design of New Hypusination Inhibitors [PDF]
Frontiers in Chemistry, 2020 Translation factor 5A (eIF5A) is one of the most conserved proteins involved in protein synthesis. It plays a key role during the elongation of polypeptide chains, and its activity is critically dependent on hypusination, a post-translational ...
Mattia D'Agostino +9 more
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Interplay between Alba and Cren7 Regulates Chromatin Compaction in Sulfolobus solfataricus [PDF]
Biomolecules, 2022 Chromatin compaction and regulation are essential processes for the normal function of all organisms, yet knowledge on how archaeal chromosomes are packed into higher-order structures inside the cell remains elusive.
Marc Kenneth M. Cajili, Eloise I. Prieto
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Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus [PDF]
FEBS Open Bio, 2020 During translation initiation, the heterotrimeric archaeal translation initiation factor 2 (aIF2) recruits the initiator tRNAi to the small ribosomal subunit.
Marco Kaiser +5 more
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The Carbon Switch at the Level of Pyruvate and Phosphoenolpyruvate in Sulfolobus solfataricus P2 [PDF]
Frontiers in Microbiology, 2019 Sulfolobus solfataricus P2 grows on different carbohydrates as well as alcohols, peptides and amino acids. Carbohydrates such as D-glucose or D-galactose are degraded via the modified, branched Entner–Doudoroff (ED) pathway whereas growth on peptides ...
Patrick Haferkamp +6 more
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Systems biology of the modified branched Entner-Doudoroff pathway in Sulfolobus solfataricus. [PDF]
PLoS ONE, 2017 Sulfolobus solfataricus is a thermoacidophilic Archaeon that thrives in terrestrial hot springs (solfatares) with optimal growth at 80°C and pH 2-4. It catabolizes specific carbon sources, such as D-glucose, to pyruvate via the modified Entner-Doudoroff (
Ana Sofia Figueiredo +8 more
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Membrane Association and Catabolite Repression of the Sulfolobus solfataricus α-Amylase [PDF]
Microorganisms, 2015 Sulfolobus solfataricus is a thermoacidophilic member of the archaea whose envelope consists of an ether-linked lipid monolayer surrounded by a protein S-layer.
Edith Soo, Deepak Rudrappa, Paul Blum
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An L213A variant of β-glycosidase from Sulfolobus solfataricus with increased α-L-arabinofuranosidase activity converts ginsenoside Rc to compound K. [PDF]
PLoS ONE, 2018 Compound K (C-K) is a crucial pharmaceutical and cosmetic component because of disease prevention and skin anti-aging effects. For industrial application of this active compound, the protopanaxadiol (PPD)-type ginsenosides should be transformed to C-K. β-
Ji-Hyeon Choi +2 more
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Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases. [PDF]
ProteinsABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
Quintana-Armas AX +3 more
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Improved conversion of ginsenoside Rb1 to compound K by semi-rational design of Sulfolobus solfataricus β-glycosidase [PDF]
AMB Express, 2017 Ginsenoside compound K has been used as a key nutritional and cosmetic component because of its anti-fatigue and skin anti-aging effects. β-Glycosidase from Sulfolobus solfataricus (SS-BGL) is known as the most efficient enzyme for compound K production.
Kyung-Chul Shin +3 more
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