Results 41 to 50 of about 10,749 (205)
Applied Sciences, 2021 A triple mutant of NADP(H)-dependent malate dehydrogenase from thermotolerant Thermococcus kodakarensis has an altered cofactor preference for NAD+, as well as improved malate production compared to wildtype malate dehydrogenase.
Ravneet Mandair +2 more
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Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition
eLife, 2015 The adaptive prokaryotic immune system CRISPR-Cas provides RNA-mediated protection from invading genetic elements. The fundamental basis of the system is the ability to capture small pieces of foreign DNA for incorporation into the genome at the CRISPR ...
Clare Rollie +4 more
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The Chromosome Replication Machinery of the Archaeon Sulfolobus solfataricus [PDF]
Journal of Biological Chemistry, 2006 In the three domains of life, the archaea, bacteria, and eukarya, there are two general lineages of DNA replication proteins: the bacterial and the eukaryal/archaeal lineages. The hyperthermophilic archaeon Sulfolobus solfataricus provides an attractive model for biochemical study of DNA replication.
Iain G, Duggin, Stephen D, Bell
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Responses of hyperthermophilic crenarchaea to UV irradiation [PDF]
, 2007 This work was supported by a dedicated functional genomics grant from the Swedish Research Council and the Swedish Graduate Research School in Genomics and Bioinformatics to RB, and by grants from the Wellcome Trust and BBSRC to MFW.Background: DNA ...
Lundgren, Magnus, +15 more
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, 2013 Raw data files of Sulfolobus solfataricus<strong>Tilt Series Date:</strong> 2013-11-14</p> <strong>Data Taken By:</strong> Rasika Ramdasi</p> <strong>Species / Specimen:</strong> Sulfolobus solfataricus</
Ramdasi, Rasika
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Hot and crispy : CRISPR-Cas systems in the hyperthermophile Sulfolobus solfataricus [PDF]
, 2013 The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas (CRISPR-associated) genes are widely spread in bacteria and archaea, representing an intracellular defence system against invading viruses and plasmids.
Zhang, Jing +2 more
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A Heterotrimeric PCNA in the Hyperthermophilic Archaeon Sulfolobus solfataricus [PDF]
Molecular Cell, 2003 The sliding clamp, PCNA, of the archaeon Sulfolobus solfataricus P2 is a heterotrimer of three distinct subunits (PCNA1, 2, and 3) that assembles in a defined manner. The PCNA heterotrimer, but not individual subunits, stimulates the activities of the DNA polymerase, DNA ligase I, and the flap endonuclease (FEN1) of S. solfataricus.
Dionne, Isabelle +4 more
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Nature Communications, 2019 The S-layer is a proteinaceous envelope often found in bacterial and archaeal cells. Here, the authors use CRISPR-based technology to silence slaB, encoding the S-layer membrane anchor, to show that an intact S-layer is important for cell division and ...
Isabelle Anna Zink +5 more
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Microbial Cell Factories, 2007 Background Exposure to nickel (Ni) and its chemical derivatives has been associated with severe health effects in human. On the contrary, poor knowledge has been acquired on target physiological processes or molecular mechanisms of this metal in model ...
Scaloni Andrea +6 more
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Biochemical, transcriptional and translational evidences of the phenol-meta-degradation pathway by the hyperthermophilic Sulfolobus solfataricus 98/2. [PDF]
PLoS ONE, 2013 Phenol is a widespread pollutant and a model molecule to study the biodegradation of monoaromatic compounds. After a first oxidation step leading to catechol in mesophilic and thermophilic microorganisms, two main routes have been identified depending on
Alexia Comte +7 more
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